GENE:AKIRIN2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AKIRIN2 |
| FullNmae | akirin 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21407 |
| EnsembleID | ENSG00000135334 |
| Uniprot | Q53H80 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AKIRIN2 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| AKIRIN2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AKIRIN2 | GO:0000122,GO:0000785,GO:0002250,GO:0002821,GO:0003712,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0006606,GO:0008284,GO:0009792,GO:0010629,GO:0016020,GO:0017053,GO:0019899,GO:0021987,GO:0030674,GO:0031144,GO:0032496,GO:0032755,GO:0042742,GO:0042802,GO:0045087,GO:0045089,GO:0045089,GO:0045944,GO:0045944,GO:0050871,GO:0051147,GO:0071630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | AKIRIN2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | AKIRIN2 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | AKIRIN2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | AKIRIN2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | AKIRIN2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | AKIRIN2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | AKIRIN2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | AKIRIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AKIRIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AKIRIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AKIRIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | AKIRIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AKIRIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | AKIRIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000BE495 | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000046CDA6 | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | AKIRIN2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDK2 | AKIRIN2 | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SORBS3 | AKIRIN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RAN | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| CCDC85B | AKIRIN2 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PSMB2 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| HSD17B14 | AKIRIN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYOZ3 | AKIRIN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RNF123 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| UBAC1 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| SPG21 | AKIRIN2 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| SIRT1 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPF | AKIRIN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ELAVL1 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| TOMM34 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| RGPD5 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB3 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| MESD | AKIRIN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| LNX1 | AKIRIN2 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PPID | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| IPO9 | AKIRIN2 | 25348397 | N/A | physical interaction | ComPPI |
| NTAQ1 | AKIRIN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AKIRIN2 | RGPD8 | 25348397 | N/A | physical interaction | ComPPI |
| AKIRIN2 | AKIRIN1 | 25348397 | N/A | physical interaction | ComPPI |
| AKIRIN2 | BUD31 | 25348397 | N/A | physical interaction | ComPPI |
| AKIRIN2 | RGPD3 | 25348397 | N/A | physical interaction | ComPPI |
| AKIRIN2 | AKIRIN2 | 24234451 | physical association | two hybrid array,two hybrid prey pooling approach | IntAct |
