GENE：VSIR
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | VSIR |
| FullNmae | V-set immunoregulatory receptor |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:30085 |
| EnsembleID | ENSG00000107738 |
| Uniprot | Q9H7M9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| VSIR | immunogenic | 36579538 | Through literature reviews, a total of 108 ICD-related genes were identified (Supplement Table S1). | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| VSIR | GO:0005515,GO:0005886,GO:0005886,GO:0010628,GO:0010950,GO:0019899,GO:0030335,GO:0031638,GO:0032689,GO:0032693,GO:0032700,GO:0032720,GO:0042802,GO:0045591,GO:0046636,GO:0050776,GO:0061133,GO:0120158,GO:2000562,GO:2000565 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| VSIR | hsa:64115 | path:hsa04514 | Cell adhesion molecules - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | VSIR | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | VSIR | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | VSIR | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | VSIR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000BD6DC | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009EA8F | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E728C | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F9738 | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000ECE9C | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E02F2 | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001A7A | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000235862 | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | VSIR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BCD9C | VSIR | 25416803 28261881 | mrna cleavage,inhibition | array technology,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TMEM218 | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TMEM100 | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SMCO4 | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ATP6V0C | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SMAD3 | VSIR | 15231748 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PLSCR1 | VSIR | 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| APOD | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TNF | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VAMP3 | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | CNIH3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | SLC35B4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | PLPPR2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | SLC35B1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | ASGR1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | CLRN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | TMEM97 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | TSPO2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | MS4A13 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | NRAC | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | TMEM229B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | BMP10 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| DOLK | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCL4L1 | VSIR | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VSIR | VSIR | 24234451 26228159 | physical association | anti tag coimmunoprecipitation,cross-linking study,pull down | IntAct |