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GENE：CCNE2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CCNE2
FullNmae cyclin E2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1590
EnsembleID ENSG00000175305
Uniprot O96020

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CCNE2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNE2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CCNE2 GO:0000079,GO:0000079,GO:0000082,GO:0000723,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005829,GO:0006270,GO:0007129,GO:0016538,GO:0019901,GO:0032880,GO:0051301,GO:0097134,GO:0097135

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CCNE2 hsa:9134 path:hsa04110 Cell cycle - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa04114 Oocyte meiosis - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa04218 Cellular senescence - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa04934 Cushing syndrome - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05161 Hepatitis B - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05162 Measles - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05200 Pathways in cancer - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05215 Prostate cancer - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05222 Small cell lung cancer - Homo sapiens (human)
CCNE2 hsa:9134 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CCNE2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 CCNE2 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CCNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CCNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CCNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CCNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CCNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CCNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CHD8 CCNE2 19255092 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001D69F6 CCNE2 18834857 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000008DA94 CCNE2 22183793 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000012A1DD CCNE2 22183793 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000171525 CCNE2 22183793 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002152A8 CCNE2 22384020 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000EED18 CCNE2 17914404 19461653 rna interference,inhibition array technology,western blot,miRNA interference luciferase reporter assay miRSponge
URS000027352D CCNE2 19461653 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002C7B2B CCNE2 19461653 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00001F5B39 CCNE2 21418558 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00003758F0 CCNE2 21418558 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00000F6E49 CCNE2 19956200 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000F6E49 CCNE2 19956200 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00002C7B2B CCNE2 19461653 23446348 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS000027352D CCNE2 19461653 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000EED18 CCNE2 17914404 19461653 23446348 25416803 mrna cleavage,inhibition array technology,western blot,clip,miRNA interference luciferase reporter assay TarBase
URS00001D69F6 CCNE2 18834857 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00002152A8 CCNE2 22384020 25416803 28120942 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001F5B39 CCNE2 21418558 23446348 25416803 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS00003758F0 CCNE2 21418558 23446348 25416803 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS000008DA94 CCNE2 22183793 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000012A1DD CCNE2 22183793 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000171525 CCNE2 22183793 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00002FC5B0 CCNE2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000C85B2 CCNE2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003BD367 CCNE2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001D6605 CCNE2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 CCNE2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A CCNE2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 CCNE2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D CCNE2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C CCNE2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 CCNE2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 CCNE2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 CCNE2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 CCNE2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 CCNE2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004ACAAA CCNE2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 CCNE2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000042B108 CCNE2 25416803 28176879 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000065D58 CCNE2 25416803 26555189 27431942 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00000C0D3F CCNE2 25416803 27517917 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS00002E92A8 CCNE2 25416803 26057453 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SKP1 CCNE2 25361965 interaction type N/A PTMCode2
CCNE2 SKP1 25361965 interaction type N/A PTMCode2
CDKN1A CCNE2 25361965 interaction type N/A PTMCode2
CCNE2 CDKN1A 25361965 interaction type N/A PTMCode2
CDKN1B CCNE2 25361965 interaction type N/A PTMCode2
CCNE2 CDKN1B 25361965 interaction type N/A PTMCode2
SKP2 CCNE2 25361965 interaction type N/A PTMCode2
CCNE2 SKP2 25361965 interaction type N/A PTMCode2
CDK2 CCNE2 25361965 interaction type N/A PTMCode2
CCNE2 CDK2 25361965 interaction type N/A PTMCode2
CCNE2 CDK3 25361965 interaction type N/A PTMCode2
CDK3 CCNE2 25361965 interaction type N/A PTMCode2
CCNE2 CDKN1C 25361965 interaction type N/A PTMCode2
CDKN1C CCNE2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CKS1B CCNE2 25348397 N/A physical interaction ComPPI
PCNA CCNE2 25348397 N/A physical interaction ComPPI
CDKN1A CCNE2 14525934 15232106 24234451 24358021 25348397 9840943 physical association anti bait coimmunoprecipitation,two hybrid,molecular sieving,protein array,physical interaction,two hybrid ComPPI,HPRD,IntAct
CDKN1B CCNE2 14525934 17254966 24234451 24358021 25348397 9840943 9858585 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
FBXW7 CCNE2 19084516 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RBL2 CCNE2 17531812 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
CDKN1C CCNE2 14525934 24234451 25348397 9840943 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SUMO2 CCNE2 14525934 16620772 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CCNE2 SUMO3 14525934 16620772 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CCNE2 ORC3 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
CCNE2 CDK2 14525934 15232106 23455922 23602568 24234451 24358021 25348397 25852190 26496610 9840943 9858585 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,protein array,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CCNE2 CDK3 14525934 24234451 25348397 9840943 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CCNE2 PTEN 25348397 N/A physical interaction ComPPI
CCNE2 H1-1 25348397 N/A physical interaction ComPPI
CCNE2 APP 25348397 N/A physical interaction ComPPI
CCNE2 ZDHHC17 25348397 N/A physical interaction ComPPI
CCNE2 L3HYPDH 25348397 N/A physical interaction ComPPI
CCNE2 SCML2 24234451 24358021 25348397 physical association molecular sieving,pull down,physical interaction ComPPI,IntAct
CCNE2 AURKA 24234451 24358021 25348397 physical association molecular sieving ComPPI,IntAct
CCNE2 CCNB2 24234451 24358021 25348397 physical association molecular sieving ComPPI,IntAct
ITGB1 CCNE2 24234451 30021884 physical association cross-linking study IntAct
RALY CCNE2 24234451 30021884 physical association cross-linking study IntAct
HNRNPC CCNE2 24234451 30021884 physical association cross-linking study IntAct
GSK3B CCNE2 27898060 9840943 N/A N/A OmniPath

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