Gene Information gene info

  1. Home

GENE：BRCC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BRCC3
FullNmae BRCA1/BRCA2-containing complex subunit 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24185
EnsembleID ENSG00000185515
Uniprot P46736

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BRCC3 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BRCC3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BRCC3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BRCC3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BRCC3 GO:0000151,GO:0000152,GO:0000922,GO:0004843,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0006282,GO:0006302,GO:0006302,GO:0007095,GO:0008237,GO:0008237,GO:0010165,GO:0010212,GO:0030234,GO:0031593,GO:0031593,GO:0044818,GO:0045739,GO:0046872,GO:0051301,GO:0061578,GO:0061578,GO:0070531,GO:0070531,GO:0070531,GO:0070536,GO:0070536,GO:0070552,GO:0070552,GO:0071479,GO:0140492,GO:0140861,GO:1900227,GO:1900227,GO:2000001

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BRCC3 hsa:79184 path:hsa03440 Homologous recombination - Homo sapiens (human)
BRCC3 hsa:79184 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BARD1 BRCC3 11877377 14636569 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561 23180781 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
BRCA1 BRCC3 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561 26192618 interaction type N/A ACSN
BRCC3 TP53BP1 11042216 11877378 17243194 18087291 19342239 20646866 26192618 9748285 interaction type N/A ACSN
BABAM2 BRCC3 17353931 23180781 physical association anti tag coimmunoprecipitation InnateDB
BRCC3 BRCA2 14636569 23180781 physical association anti tag coimmunoprecipitation InnateDB
BRCC3 BABAM2 14636569 23180781 physical association anti tag coimmunoprecipitation InnateDB
BRCC3 BRCA1 14636569 23180781 physical association anti tag coimmunoprecipitation InnateDB
BRCC3 BARD1 14636569 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBB BRCC3 14636569 23180781 physical association enzymatic study InnateDB

Source Target Pmid Interactiontype Methods Database
AR BRCC3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 BRCC3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF BRCC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BRCC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 BRCC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000058BB84 BRCC3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC BRCC3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000034979B BRCC3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB BRCC3 21572407 23446348 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000B7E30 BRCC3 21572407 23446348 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CF056 BRCC3 21572407 23446348 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000028DE3F BRCC3 21572407 23446348 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000052EA98 BRCC3 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 BRCC3 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000D5FFC BRCC3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA BRCC3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 BRCC3 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BRCA1 BRCC3 25361965 interaction type N/A PTMCode2
BRCC3 BRCA1 25361965 interaction type N/A PTMCode2
BARD1 BRCC3 25361965 interaction type N/A PTMCode2
BRCC3 BARD1 25361965 interaction type N/A PTMCode2
TP53 BRCC3 25361965 interaction type N/A PTMCode2
BRCC3 TP53 25361965 interaction type N/A PTMCode2
CAND1 BRCC3 25361965 interaction type N/A PTMCode2
BRCC3 CAND1 25361965 interaction type N/A PTMCode2
USP7 BRCC3 25361965 interaction type N/A PTMCode2
BRCC3 USP7 25361965 interaction type N/A PTMCode2
BRCA2 BRCC3 25361965 interaction type N/A PTMCode2
BRCC3 BRCA2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DEF6 BRCC3 25348397 N/A physical interaction ComPPI
ATP5PO BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 BRCC3 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
UBE2D1 BRCC3 25348397 N/A physical interaction ComPPI
MCM2 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOC8 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABRAXAS2 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD2AP BRCC3 25348397 N/A physical interaction ComPPI
GRB2 BRCC3 25348397 N/A physical interaction ComPPI
SMARCD1 BRCC3 25348397 N/A physical interaction ComPPI
COPS5 BRCC3 25348397 N/A physical interaction ComPPI
USP7 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAXIP1 BRCC3 25348397 N/A physical interaction ComPPI
IFNAR1 BRCC3 25348397 N/A physical interaction ComPPI
UBC BRCC3 19214193 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG6 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
WWP2 BRCC3 25348397 N/A physical interaction ComPPI
KSR2 BRCC3 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
RAD51 BRCC3 25348397 N/A physical interaction ComPPI
BRCA2 BRCC3 25348397 N/A physical interaction ComPPI
E2F5 BRCC3 25348397 N/A physical interaction ComPPI
HUWE1 BRCC3 25348397 N/A physical interaction ComPPI
SUMO2 BRCC3 25348397 N/A physical interaction ComPPI
SF3A1 BRCC3 25348397 N/A physical interaction ComPPI
SUPT16H BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM28 BRCC3 25348397 N/A physical interaction ComPPI
SPAG9 BRCC3 25348397 N/A physical interaction ComPPI
MDC1 BRCC3 24234451 25348397 29656893 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NR3C1 BRCC3 25348397 N/A physical interaction ComPPI
CAND1 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GPHN BRCC3 25348397 N/A physical interaction ComPPI
BARD1 BRCC3 25348397 N/A physical interaction ComPPI
BACH1 BRCC3 25348397 N/A physical interaction ComPPI
HNRNPR BRCC3 25348397 N/A physical interaction ComPPI
BRCA1 BRCC3 14525934 14636569 19202061 24234451 25348397 29656893 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,proximity-dependent biotin identification ComPPI,HPRD,IntAct
MTA2 BRCC3 25348397 N/A physical interaction ComPPI
SNAPC5 BRCC3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UIMC1 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 BABAM2 17353931 19615732 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 TP53 25348397 N/A physical interaction ComPPI
BRCC3 DDOST 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 NDUFA10 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 ABRAXAS1 18077395 19615732 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 CCDC6 25348397 N/A physical interaction ComPPI
BRCC3 HDAC1 25348397 N/A physical interaction ComPPI
BRCC3 RABEP2 25348397 N/A physical interaction ComPPI
BRCC3 PPP4R3A 25348397 N/A physical interaction ComPPI
BRCC3 LARP7 25348397 N/A physical interaction ComPPI
BRCC3 WDHD1 25348397 N/A physical interaction ComPPI
BRCC3 FANCG 25348397 N/A physical interaction ComPPI
BRCC3 TFDP3 25348397 N/A physical interaction ComPPI
BRCC3 CENPA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 NUMA1 25348397 N/A physical interaction ComPPI
BRCC3 TNS1 25348397 N/A physical interaction ComPPI
BRCC3 FANCA 25348397 N/A physical interaction ComPPI
BRCC3 CRBN 25348397 N/A physical interaction ComPPI
BRCC3 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MRPL1 BRCC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCC3 H2AZ1 19202061 27898060 inhibition N/A OmniPath
BRCC3 H2BC11 19202061 27898060 inhibition N/A OmniPath
BRCC3 H2AC11 20656690 27898060 inhibition N/A OmniPath

Visualization










  Return