GENE：NTSR1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | NTSR1 |
| FullNmae | neurotensin receptor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8039 |
| EnsembleID | ENSG00000101188 |
| Uniprot | P30989 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| NTSR1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| NTSR1 | GO:0001659,GO:0003085,GO:0003254,GO:0004930,GO:0005515,GO:0005783,GO:0005794,GO:0005886,GO:0005886,GO:0005886,GO:0007186,GO:0007218,GO:0007218,GO:0007218,GO:0007268,GO:0007612,GO:0008344,GO:0009898,GO:0009986,GO:0010628,GO:0014049,GO:0014054,GO:0016492,GO:0016492,GO:0016492,GO:0032280,GO:0033993,GO:0042802,GO:0043065,GO:0043066,GO:0043195,GO:0043197,GO:0043198,GO:0043204,GO:0043576,GO:0044877,GO:0045121,GO:0050965,GO:0051280,GO:0051281,GO:0060732,GO:0070779,GO:0071545,GO:0090238,GO:0097151,GO:0098712 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| NTSR1 | hsa:4923 | path:hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
| NTSR1 | hsa:4923 | path:hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | NTSR1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | NTSR1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | NTSR1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | NTSR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | NTSR1 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | NTSR1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000060AABB | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000568FF8 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A9FB9 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0BB4 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000018E6CD | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759B6A | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F1B8C | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000023F008 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CCD18 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D5391 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000235862 | NTSR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ARRB2 | NTSR1 | 11279203 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| NTSR1 | NTS | 11559354 14525934 16087676 17620610 24234451 25348397 | N/A | experimental interaction detection,light scattering,molecular sieving,physical interaction | ComPPI,HPRD,IntAct |
| NTS | NTSR1 | 11559354 11811984 1331689 16087676 1694443 17620610 27898060 | stimulant | N/A | OmniPath |