Gene Information gene info

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GENE：FOXC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FOXC1
FullNmae forkhead box C1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3800
EnsembleID ENSG00000054598
Uniprot Q12948

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FOXC1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FOXC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FOXC1 GO:0000122,GO:0000785,GO:0000792,GO:0000976,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001228,GO:0001525,GO:0001541,GO:0001654,GO:0001657,GO:0001701,GO:0001756,GO:0001822,GO:0001945,GO:0001958,GO:0001974,GO:0003275,GO:0003677,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0006355,GO:0006357,GO:0007219,GO:0007507,GO:0008283,GO:0008283,GO:0008301,GO:0008354,GO:0009653,GO:0010628,GO:0010718,GO:0014031,GO:0014032,GO:0016477,GO:0016477,GO:0016525,GO:0021549,GO:0030154,GO:0030199,GO:0030203,GO:0032808,GO:0035050,GO:0036438,GO:0038084,GO:0042475,GO:0043010,GO:0043388,GO:0043565,GO:0045618,GO:0045893,GO:0045893,GO:0045930,GO:0045944,GO:0045944,GO:0045944,GO:0046620,GO:0048010,GO:0048341,GO:0048844,GO:0055010,GO:0060038,GO:0061629,GO:0070098,GO:0071364,GO:0072010,GO:0097746,GO:0140297,GO:1901491,GO:1901534,GO:1902038,GO:1902257,GO:1904798,GO:1990841,GO:1990869

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 FOXC1 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
ETS1 FOXC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FOXC1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 FOXC1 21878914 22120723 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 FOXC1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FOXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FOXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FOXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FOXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FOXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FOXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FOXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BRCA1 FOXC1 22120723 trascriptional regulation,stimulation inferred by curator TFlink
EZH2 FOXC1 21465172 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029D9F1 FOXC1 21400511 rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS000029D9F1 FOXC1 20371350 21400511 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay TarBase
URS000041FA2C FOXC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D FOXC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 FOXC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D FOXC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 FOXC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000012A1DD FOXC1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F0C23 FOXC1 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000008DA94 FOXC1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E5ECC FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD FOXC1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 FOXC1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C FOXC1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 FOXC1 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075ABF4 FOXC1 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 FOXC1 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000040828B FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 FOXC1 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000003575B FOXC1 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000192A75 FOXC1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 FOXC1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027080C FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000FC8EB FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F FOXC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED FOXC1 20371350 25416803 26198045 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip TarBase
URS000075C1E1 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 FOXC1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000032BD73 FOXC1 25416803 27050992 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 FOXC1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HOXB9 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GATAD2B FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HSPA8 FOXC1 25348397 N/A physical interaction ComPPI
HSPBP1 FOXC1 25348397 N/A physical interaction ComPPI
PPP2R1A FOXC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PBX2 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
H2BC4 FOXC1 25348397 N/A physical interaction ComPPI
AIM2 FOXC1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
FOXC2 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EGLN3 FOXC1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
FLNA FOXC1 15684392 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,fluorescence microscopy ComPPI,IntAct
PPP2CB FOXC1 25348397 N/A physical interaction ComPPI
C1QBP FOXC1 18676636 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,pull down,fluorescence microscopy ComPPI,IntAct,OmniPath
HMGB1 FOXC1 11748221 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LDB1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SOX2 FOXC1 25348397 N/A physical interaction ComPPI
TFCP2 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PPP2R2A FOXC1 24234451 25348397 26496610 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
MECP2 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SMARCA1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DLX5 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BCOR FOXC1 24234451 25348397 27505670 association tandem affinity purification ComPPI,IntAct
NFIC FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RECQL FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ELAVL1 FOXC1 25348397 N/A physical interaction ComPPI
DACH1 FOXC1 25348397 N/A physical interaction ComPPI
SALL1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PITX2 FOXC1 25348397 N/A anti tag coimmunoprecipitation ComPPI
SATB1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DDX39A FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MEIS1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PBX1 FOXC1 15684392 24234451 25348397 25609649 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,array technology,physical interaction,fluorescence microscopy,tandem affinity purification ComPPI,IntAct
SMARCA5 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FBXW11 FOXC1 25348397 N/A physical interaction ComPPI
SATB2 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
POU2F1 FOXC1 25348397 N/A physical interaction ComPPI
NFIX FOXC1 25348397 N/A physical interaction ComPPI
CREB1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXS1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HOXD13 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HOXC13 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PPP2R2D FOXC1 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PRMT6 FOXC1 25348397 N/A physical interaction ComPPI
VARS1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
H2BC11 FOXC1 25348397 N/A physical interaction ComPPI
FOXC1 CCDC8 25348397 N/A physical interaction ComPPI
FOXC1 METTL6 25348397 N/A physical interaction ComPPI
FOXC1 C5ORF24 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXC1 NDUFA11 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXC1 TP53 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXC1 UBP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXC1 FOXD4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXC1 FOXJ2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXC1 PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
FOXC1 FOS 24234451 25303530 association chromatin immunoprecipitation assay IntAct
TFAP2C FOXC1 24234451 25303530 association chromatin immunoprecipitation assay IntAct
JUN FOXC1 24234451 25303530 association chromatin immunoprecipitation assay IntAct
FOXC1 FOXA1 24234451 25303530 association chromatin immunoprecipitation assay IntAct
FOXC1 ESR1 24234451 25303530 association chromatin immunoprecipitation assay IntAct
RARG FOXC1 24234451 25303530 association chromatin immunoprecipitation assay IntAct
GATA3 FOXC1 24234451 25303530 association chromatin immunoprecipitation assay IntAct
FOXC1 RARA 24234451 25303530 association chromatin immunoprecipitation assay IntAct
FOXC1 FOXC1 24234451 25609649 association tandem affinity purification IntAct
FOXC1 RBPJ 21871448 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00007E4B8E FOXC1 25031703 28529080 direct interaction,inhibition quantitative pcr lncRInter

Visualization










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