GENE:FOXC1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | FOXC1 |
FullNmae | forkhead box C1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:3800 |
EnsembleID | ENSG00000054598 |
Uniprot | Q12948 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
FOXC1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
FOXC1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
FOXC1 | GO:0000122,GO:0000785,GO:0000792,GO:0000976,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001228,GO:0001525,GO:0001541,GO:0001654,GO:0001657,GO:0001701,GO:0001756,GO:0001822,GO:0001945,GO:0001958,GO:0001974,GO:0003275,GO:0003677,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0006355,GO:0006357,GO:0007219,GO:0007507,GO:0008283,GO:0008283,GO:0008301,GO:0008354,GO:0009653,GO:0010628,GO:0010718,GO:0014031,GO:0014032,GO:0016477,GO:0016477,GO:0016525,GO:0021549,GO:0030154,GO:0030199,GO:0030203,GO:0032808,GO:0035050,GO:0036438,GO:0038084,GO:0042475,GO:0043010,GO:0043388,GO:0043565,GO:0045618,GO:0045893,GO:0045893,GO:0045930,GO:0045944,GO:0045944,GO:0045944,GO:0046620,GO:0048010,GO:0048341,GO:0048844,GO:0055010,GO:0060038,GO:0061629,GO:0070098,GO:0071364,GO:0072010,GO:0097746,GO:0140297,GO:1901491,GO:1901534,GO:1902038,GO:1902257,GO:1904798,GO:1990841,GO:1990869 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ESR1 | FOXC1 | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
ETS1 | FOXC1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | FOXC1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA3 | FOXC1 | 21878914 22120723 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXA1 | FOXC1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | FOXC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | FOXC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | FOXC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | FOXC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | FOXC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | FOXC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | FOXC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
BRCA1 | FOXC1 | 22120723 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EZH2 | FOXC1 | 21465172 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000029D9F1 | FOXC1 | 21400511 | rna interference,inhibition | experimental interaction detection,western blot,miRNA interference luciferase reporter assay | miRSponge |
URS000029D9F1 | FOXC1 | 20371350 21400511 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay | TarBase |
URS000041FA2C | FOXC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000070B1D | FOXC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000AA464 | FOXC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000005481D | FOXC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000451A1 | FOXC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000012A1DD | FOXC1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001F0C23 | FOXC1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000008DA94 | FOXC1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00003E5ECC | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C36BD | FOXC1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001FA076 | FOXC1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000044FD7 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000000EF0B | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E226A | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001A6D0C | FOXC1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002075FA | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000042E1F | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000DDD35 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000039E1E1 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B7E30 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000600E6 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000346991 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041E949 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002B3783 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000298BA3 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000039A052 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000EEE35 | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006F90B | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000025EABA | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000285DCB | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EFEC1 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000001EB3 | FOXC1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000075ABF4 | FOXC1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002394F5 | FOXC1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000040828B | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000D2680 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C48FA | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002FC5B0 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000023BE29 | FOXC1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000003575B | FOXC1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000192A75 | FOXC1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000235862 | FOXC1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000027080C | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000FC8EB | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008F0CF | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000AF45F | FOXC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000005A8ED | FOXC1 | 20371350 25416803 26198045 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,clip | TarBase |
URS000075C1E1 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002A8BC6 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032AE90 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005586D0 | FOXC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032BD73 | FOXC1 | 25416803 27050992 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CDK2 | FOXC1 | 22135298 | phosphorylation | N/A | PhosphoSite |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
HOXB9 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
GATAD2B | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
HSPA8 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
HSPBP1 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
PPP2R1A | FOXC1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PBX2 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
H2BC4 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
AIM2 | FOXC1 | 24234451 25348397 25665578 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
FOXC2 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
EGLN3 | FOXC1 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
FLNA | FOXC1 | 15684392 24234451 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,fluorescence microscopy | ComPPI,IntAct |
PPP2CB | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
C1QBP | FOXC1 | 18676636 24234451 25348397 27898060 | physical association | anti tag coimmunoprecipitation,two hybrid,pull down,fluorescence microscopy | ComPPI,IntAct,OmniPath |
HMGB1 | FOXC1 | 11748221 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
LDB1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
SOX2 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
TFCP2 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
PPP2R2A | FOXC1 | 24234451 25348397 26496610 28330616 | association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
MECP2 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
SMARCA1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
DLX5 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
BCOR | FOXC1 | 24234451 25348397 27505670 | association | tandem affinity purification | ComPPI,IntAct |
NFIC | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
RECQL | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
ELAVL1 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
DACH1 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
SALL1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
PITX2 | FOXC1 | 25348397 | N/A | anti tag coimmunoprecipitation | ComPPI |
SATB1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
DDX39A | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
MEIS1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
PBX1 | FOXC1 | 15684392 24234451 25348397 25609649 | colocalization,association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,array technology,physical interaction,fluorescence microscopy,tandem affinity purification | ComPPI,IntAct |
SMARCA5 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FBXW11 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
SATB2 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
POU2F1 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
NFIX | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
CREB1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FOXS1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
HOXD13 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
HOXC13 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
PPP2R2D | FOXC1 | 24234451 25348397 28330616 | association | pull down,physical interaction | ComPPI,IntAct |
PRMT6 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
VARS1 | FOXC1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
H2BC11 | FOXC1 | 25348397 | N/A | physical interaction | ComPPI |
FOXC1 | CCDC8 | 25348397 | N/A | physical interaction | ComPPI |
FOXC1 | METTL6 | 25348397 | N/A | physical interaction | ComPPI |
FOXC1 | C5ORF24 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FOXC1 | NDUFA11 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FOXC1 | TP53 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FOXC1 | UBP1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FOXC1 | FOXD4 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FOXC1 | FOXJ2 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FOXC1 | PYHIN1 | 24234451 25348397 25665578 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
FOXC1 | FOS | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
TFAP2C | FOXC1 | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
JUN | FOXC1 | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
FOXC1 | FOXA1 | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
FOXC1 | ESR1 | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
RARG | FOXC1 | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
GATA3 | FOXC1 | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
FOXC1 | RARA | 24234451 25303530 | association | chromatin immunoprecipitation assay | IntAct |
FOXC1 | FOXC1 | 24234451 25609649 | association | tandem affinity purification | IntAct |
FOXC1 | RBPJ | 21871448 27898060 | stimulant | N/A | OmniPath |