GENE:TEAD1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TEAD1 |
| FullNmae | TEA domain transcription factor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11714 |
| EnsembleID | ENSG00000187079 |
| Uniprot | P28347 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TEAD1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TEAD1 | GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0003677,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005667,GO:0006357,GO:0030307,GO:0035329,GO:0035329,GO:0035329,GO:0045893,GO:0045944,GO:0045944,GO:0048568,GO:0065003,GO:0140552,GO:0140552,GO:1902895,GO:1990837 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| TEAD1 | hsa:7003 | path:hsa04390 | Hippo signaling pathway - Homo sapiens (human) |
| TEAD1 | hsa:7003 | path:hsa04392 | Hippo signaling pathway - multiple species - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TEAD1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | TEAD1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | TEAD1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TEAD1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | TEAD1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | TEAD1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TEAD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ATF1 | TEAD1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | TEAD1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00003CF1AD | TEAD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000F31F4 | TEAD1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | TEAD1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | TEAD1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | TEAD1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000054A671 | TEAD1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FA076 | TEAD1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C36BD | TEAD1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031BC7D | TEAD1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D2680 | TEAD1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | TEAD1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | TEAD1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BD1DE | TEAD1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002EF20A | TEAD1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | TEAD1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | TEAD1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000535FDD | TEAD1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E628F | TEAD1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | TEAD1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000036B845 | TEAD1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | TEAD1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006B702 | TEAD1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BA274 | TEAD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | TEAD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | TEAD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DD591 | TEAD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NCOA1 | TEAD1 | 25361965 | interaction type | N/A | PTMCode2 |
| TEAD1 | NCOA1 | 25361965 | interaction type | N/A | PTMCode2 |
| TEAD1 | MEF2C | 25361965 | interaction type | N/A | PTMCode2 |
| MEF2C | TEAD1 | 25361965 | interaction type | N/A | PTMCode2 |
| MEF2A | TEAD1 | 25361965 | interaction type | N/A | PTMCode2 |
| TEAD1 | MEF2A | 25361965 | interaction type | N/A | PTMCode2 |
| SRF | TEAD1 | 25361965 | interaction type | N/A | PTMCode2 |
| TEAD1 | SRF | 25361965 | interaction type | N/A | PTMCode2 |
| USP7 | TEAD1 | 25361965 | interaction type | N/A | PTMCode2 |
| TEAD1 | USP7 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMNA | TEAD1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| UBTD1 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| TBP | TEAD1 | 24234451 25348397 8423815 | N/A | pull down | ComPPI,IntAct |
| JUN | TEAD1 | 24234451 25348397 26258633 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NCOA1 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| JUND | TEAD1 | 24234451 25348397 26258633 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SRF | TEAD1 | 11136726 12061776 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| PFKM | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| ENO1 | TEAD1 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| RAD51 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| SOX2 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| ZDHHC17 | TEAD1 | 24234451 24705354 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| MEF2C | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| VGLL1 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| YAP1 | TEAD1 | 22863277 24234451 24255178 24581491 24882516 25348397 25751139 25751140 26258633 | colocalization,association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification | ComPPI,IntAct |
| VGLL4 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| INSR | TEAD1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| TRIM25 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| WWTR1 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| TEAD4 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| TEAD2 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| SKI | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| MAX | TEAD1 | 25348397 27898060 9199327 | N/A | physical interaction | ComPPI,OmniPath |
| POU2F1 | TEAD1 | 24234451 25348397 8423815 | N/A | pull down | ComPPI,IntAct |
| FOSL1 | TEAD1 | 24234451 25348397 26258633 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HLA-DMB | TEAD1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| FOXK2 | TEAD1 | 25348397 | N/A | physical interaction | ComPPI |
| GCAT | TEAD1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| TEAD1 | VG | 24234451 9869635 | physical association | far western blotting,pull down | IntAct |
| TEAD1 | TEAD1 | 24234451 8423815 | N/A | pull down | IntAct |
| TEAD1 | VGLL2 | 12376544 14762206 27898060 | N/A | N/A | OmniPath |
| MYH7 | TEAD1 | 12861002 27898060 8253797 | N/A | N/A | OmniPath |
| WWTR1 | TEAD1 | 23431053 27898060 | stimulant | N/A | OmniPath |
| YAP1 | TEAD1 | 11358867 22863277 23431053 24255178 24581491 24882516 27898060 | stimulant | N/A | OmniPath |
