GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
WIF1 |
FullNmae |
WNT inhibitory factor 1 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:18081 |
EnsembleID |
ENSG00000156076 |
Uniprot |
Q9Y5W5 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
WIF1 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
WIF1 |
GO:0001568,GO:0005515,GO:0005576,GO:0007165,GO:0007368,GO:0007507,GO:0009952,GO:0009986,GO:0016055,GO:0017147,GO:0030178,GO:0038092,GO:0038100,GO:0045600,GO:0070697 |
KEGG Annotation:
GeneSymbol |
GeneID |
Pathway |
Pathway Name |
WIF1 |
hsa:11197 |
path:hsa04310 |
Wnt signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
WIF1 |
WNT8A |
10201374
23331499
|
stimulation |
N/A |
SignaLink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
GATA2 |
WIF1 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
YBX1 |
WIF1 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TP53 |
WIF1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
SP1 |
WIF1 |
18701434
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
DAND5 |
WIF1 |
18701434
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000237AF9 |
WIF1 |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS0000285DCB |
WIF1 |
23321667
25416803
|
mrna cleavage,inhibition |
miRNA interference luciferase reporter assay |
TarBase |
URS00004DA9DB |
WIF1 |
25416803
25486432
|
mrna cleavage,inhibition |
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
KRTAP10-8 |
WIF1 |
24234451
25348397
25416956
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
WNT11 |
WIF1 |
22986341
24234451
25348397
|
N/A |
surface plasmon resonance,surface plasmon resonance array |
ComPPI,IntAct |
WIF1 |
WNT1 |
25348397
|
N/A |
physical interaction |
ComPPI |
WIF1 |
RPL37 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
WIF1 |
ICOS |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
WIF1 |
KRTAP10-3 |
25348397
|
N/A |
physical interaction |
ComPPI |
WIF1 |
AURKA |
24234451
25348397
25640309
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
WIF1 |
FGFR4 |
24234451
25348397
25640309
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
WIF1 |
RB1CC1 |
24234451
25348397
25640309
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
WIF1 |
WNT7A |
22986341
24234451
25348397
26342861
|
N/A |
surface plasmon resonance,surface plasmon resonance array |
ComPPI,IntAct |
WIF1 |
WNT5A |
24234451
25348397
26342861
|
N/A |
surface plasmon resonance,surface plasmon resonance array |
ComPPI,IntAct |
WIF1 |
CRADD |
24234451
25348397
27107012
|
physical association |
validated two hybrid,barcode fusion genetics two hybrid |
ComPPI,IntAct |
WIF1 |
CYSRT1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
WIF1 |
WNT8A |
10201374
27898060
|
inhibition,stimulant |
N/A |
OmniPath |
Visualization