GENE:WNT3
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | WNT3 |
FullNmae | Wnt family member 3 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:12782 |
EnsembleID | ENSG00000108379 |
Uniprot | P56703 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
WNT3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
WNT3 | GO:0000902,GO:0001707,GO:0005109,GO:0005109,GO:0005125,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005788,GO:0005796,GO:0005886,GO:0007276,GO:0007411,GO:0009948,GO:0009950,GO:0010467,GO:0010628,GO:0019904,GO:0030177,GO:0030182,GO:0030182,GO:0030666,GO:0031012,GO:0035115,GO:0035116,GO:0044338,GO:0044339,GO:0045165,GO:0048018,GO:0048018,GO:0048697,GO:0048843,GO:0050767,GO:0060064,GO:0060070,GO:0060070,GO:0060070,GO:0060174,GO:0060323,GO:0061180,GO:0070062,GO:0071300,GO:0072089,GO:1904954,GO:1905474,GO:1990909,GO:1990909 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
WNT3 | hsa:7473 | path:hsa04150 | mTOR signaling pathway - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa04390 | Hippo signaling pathway - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa04550 | Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa04916 | Melanogenesis - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa04934 | Cushing syndrome - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05010 | Alzheimer disease - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05022 | Pathways of neurodegeneration - multiple diseases - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05200 | Pathways in cancer - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05205 | Proteoglycans in cancer - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05206 | MicroRNAs in cancer - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05217 | Basal cell carcinoma - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05224 | Breast cancer - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05225 | Hepatocellular carcinoma - Homo sapiens (human) |
WNT3 | hsa:7473 | path:hsa05226 | Gastric cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ROR2 | WNT3 | 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 23070005 26192618 | interaction type | N/A | ACSN |
TAB1 | WNT3 | 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005 26192618 | interaction type | N/A | ACSN |
TAB2 | WNT3 | 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005 26192618 | interaction type | N/A | ACSN |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
E2F4 | WNT3 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
GATA1 | WNT3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | WNT3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
PRDM14 | WNT3 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | WNT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | WNT3 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000F31F4 | WNT3 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | WNT3 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000FC8EB | WNT3 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000023F008 | WNT3 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001012BC | WNT3 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005F1B8C | WNT3 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000022AAA | WNT3 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075AB0E | WNT3 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001F0C23 | WNT3 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002578DA | WNT3 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000338542 | WNT3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000054DF42 | WNT3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075E2C3 | WNT3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000211070 | WNT3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
FZD1 | WNT3 | 10557084 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
WNT3A | WNT3 | 25348397 | N/A | physical interaction | ComPPI |
FZD7 | WNT3 | 18313787 21314951 24234451 25348397 | physical association | anti tag coimmunoprecipitation,pull down | ComPPI,IntAct |
WNT3 | LRP6 | 15578921 27898060 | stimulant | N/A | OmniPath |
WNT3 | FZD3 | 15578921 27898060 | stimulant | N/A | OmniPath |
WNT3 | FZD7 | 18313787 21314951 24032637 27898060 | stimulant | N/A | OmniPath |