Gene Information gene info

GENE:WNT3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WNT3
FullNmae Wnt family member 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12782
EnsembleID ENSG00000108379
Uniprot P56703

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WNT3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WNT3 GO:0000902,GO:0001707,GO:0005109,GO:0005109,GO:0005125,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005788,GO:0005796,GO:0005886,GO:0007276,GO:0007411,GO:0009948,GO:0009950,GO:0010467,GO:0010628,GO:0019904,GO:0030177,GO:0030182,GO:0030182,GO:0030666,GO:0031012,GO:0035115,GO:0035116,GO:0044338,GO:0044339,GO:0045165,GO:0048018,GO:0048018,GO:0048697,GO:0048843,GO:0050767,GO:0060064,GO:0060070,GO:0060070,GO:0060070,GO:0060174,GO:0060323,GO:0061180,GO:0070062,GO:0071300,GO:0072089,GO:1904954,GO:1905474,GO:1990909,GO:1990909

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WNT3 hsa:7473 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
WNT3 hsa:7473 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)
WNT3 hsa:7473 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
WNT3 hsa:7473 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
WNT3 hsa:7473 path:hsa04916 Melanogenesis - Homo sapiens (human)
WNT3 hsa:7473 path:hsa04934 Cushing syndrome - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05010 Alzheimer disease - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05200 Pathways in cancer - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05217 Basal cell carcinoma - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05224 Breast cancer - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
WNT3 hsa:7473 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 WNT3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 WNT3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 WNT3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 WNT3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 WNT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 WNT3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 WNT3 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 WNT3 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000FC8EB WNT3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000023F008 WNT3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC WNT3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C WNT3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA WNT3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E WNT3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 WNT3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA WNT3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000338542 WNT3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000054DF42 WNT3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 WNT3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000211070 WNT3 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
WNT3 FZD1 25361965 interaction type N/A PTMCode2
FZD1 WNT3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FZD1 WNT3 10557084 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
WNT3A WNT3 25348397 N/A physical interaction ComPPI
FZD7 WNT3 18313787 21314951 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
WNT3 LRP6 15578921 27898060 stimulant N/A OmniPath
WNT3 FZD3 15578921 27898060 stimulant N/A OmniPath
WNT3 FZD7 18313787 21314951 24032637 27898060 stimulant N/A OmniPath

Visualization