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GENE：BTG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BTG2
FullNmae BTG anti-proliferation factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1131
EnsembleID ENSG00000159388
Uniprot P78543

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BTG2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BTG2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BTG2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BTG2 GO:0000122,GO:0003714,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006281,GO:0006974,GO:0007405,GO:0007406,GO:0008285,GO:0008285,GO:0008306,GO:0009612,GO:0009952,GO:0014070,GO:0017148,GO:0021542,GO:0021954,GO:0031175,GO:0035914,GO:0043434,GO:0043524,GO:0045930,GO:0051602,GO:0060213,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BTG2 hsa:7832 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LYL1 BTG2 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR BTG2 16281084 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 BTG2 19117054 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
ETS1 BTG2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 BTG2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 BTG2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 BTG2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 BTG2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 BTG2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 BTG2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 BTG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BTG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BTG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BTG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RARA BTG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 BTG2 16581545 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXM1 BTG2 19615363 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 BTG2 17363596 trascriptional regulation,stimulation inferred by curator TFlink
PHB2 BTG2 19117054 trascriptional regulation,stimulation inferred by curator TFlink
RELA BTG2 17363596 trascriptional regulation,stimulation inferred by curator TFlink
MYB BTG2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D BTG2 17991735 19546886 \N rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D BTG2 18591254 18927107 19546886 20371350 23446999 23857284 24821435 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,nucleotide sequence identification,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS000003ABC4 BTG2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 BTG2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 BTG2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C BTG2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D BTG2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 BTG2 20371350 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000010BD8D BTG2 20371350 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 BTG2 21572407 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000055128B BTG2 21572407 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F0C23 BTG2 21572407 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 BTG2 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 BTG2 20371350 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB BTG2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001C4762 BTG2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000759EB8 BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000412AC7 BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000027352D BTG2 20371350 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075ABF4 BTG2 20371350 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB14 BTG2 20371350 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002198F3 BTG2 20371350 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000366551 BTG2 20371350 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000006B702 BTG2 20371350 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002CCA6E BTG2 20371350 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 BTG2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 BTG2 20371350 21572407 24398324 25416803 26394836 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000B989F BTG2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 BTG2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA BTG2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00006097A6 BTG2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001925C1 BTG2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB BTG2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000272A3D BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000209F04 BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000157FBE BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004A6E26 BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075A611 BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000047A8F BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000214763 BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000AA464 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001C770D BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000070B1D BTG2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000020579D BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000004BACE BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000000C73C BTG2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000017CCCB BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DEA91 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 BTG2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F BTG2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D BTG2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 BTG2 20371350 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000040EC3B BTG2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001310DE BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000519450 BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000025EABA BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA BTG2 21572407 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 BTG2 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E BTG2 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000052EA98 BTG2 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000239117 BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 BTG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD BTG2 20371350 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000021D7C8 BTG2 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 BTG2 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 BTG2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 BTG2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F BTG2 24398324 25416803 25626081 27409164 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000AB32B BTG2 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000023BE29 BTG2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 BTG2 20371350 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004977C5 BTG2 20371350 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E5E03 BTG2 20371350 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000486E0B BTG2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B2B BTG2 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000034979B BTG2 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000272039 BTG2 25416803 26394836 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000077DDE BTG2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000017EA6A BTG2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029D9F1 BTG2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A6D0C BTG2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000040FA88 BTG2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 BTG2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000553F51 BTG2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCA BTG2 25361965 interaction type N/A PTMCode2
BTG2 PRKCA 25361965 interaction type N/A PTMCode2
CNOT8 BTG2 25361965 interaction type N/A PTMCode2
BTG2 CNOT8 25361965 interaction type N/A PTMCode2
BTG2 HOXB9 25361965 interaction type N/A PTMCode2
HOXB9 BTG2 25361965 interaction type N/A PTMCode2
BTG2 PICK1 25361965 interaction type N/A PTMCode2
PICK1 BTG2 25361965 interaction type N/A PTMCode2
BTG2 CNOT7 25361965 interaction type N/A PTMCode2
CNOT7 BTG2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HOXB9 BTG2 10617598 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SKP1 BTG2 25348397 N/A physical interaction ComPPI
BTG2 PRKCA 11237868 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
BTG2 SMAD1 14525934 15542835 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BTG2 PRMT1 11856371 14525934 25348397 8663146 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
BTG2 SMAD9 25348397 N/A in vivo ComPPI
BTG2 CNOT7 11136725 24234451 25348397 25416956 physical association two hybrid,pull down,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BTG2 CNOT8 11136725 14525934 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
BTG2 PICK1 11237868 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
BTG2 HOXC8 10617598 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
BTG2 CNOT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BTG2 CNOT6L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BTG2 SKP2 19615363 22975506 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BTG2 CUL1 25348397 N/A physical interaction ComPPI
BTG2 BTRC 25348397 N/A physical interaction ComPPI
BTG2 FBXW11 25348397 N/A physical interaction ComPPI
BTG2 FBXW2 25348397 N/A physical interaction ComPPI
BTG2 FBXL3 25348397 N/A physical interaction ComPPI
BTG2 SRA1 25348397 N/A physical interaction ComPPI
BTG2 HNRNPL 25348397 N/A physical interaction ComPPI
BTG2 POPDC2 18337750 24234451 25348397 27898060 physical association two hybrid ComPPI,IntAct,OmniPath
BTG2 AR 21172304 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct,OmniPath
MAPK3 BTG2 15788397 27898060 N/A N/A OmniPath
TP53 BTG2 10669755 27898060 8944033 stimulant N/A OmniPath
MAPK14 BTG2 15788397 27898060 N/A N/A OmniPath
BTG2 NFE2L2 22493435 27898060 stimulant N/A OmniPath
MAPK1 BTG2 15788397 27898060 N/A N/A OmniPath
BTG2 CCND1 10669755 27898060 inhibition N/A OmniPath
BTG2 HOXB9 10617598 27898060 stimulant N/A OmniPath

Visualization










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