Gene Information gene info

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GENE：SLPI

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLPI
FullNmae secretory leukocyte peptidase inhibitor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11092
EnsembleID ENSG00000124107
Uniprot P03973

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLPI immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLPI GO:0003677,GO:0003729,GO:0004866,GO:0004867,GO:0004867,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005794,GO:0006955,GO:0019731,GO:0019731,GO:0019731,GO:0019899,GO:0032091,GO:0032496,GO:0035580,GO:0035821,GO:0045071,GO:0045087,GO:0045087,GO:0062023,GO:0070062

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 SLPI 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
GRN SLPI 12526812 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CEBPA SLPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IRF1 SLPI 10498899 trascriptional regulation,stimulation inferred by curator TFlink
JUN SLPI N/A trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 SLPI N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 SLPI N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A SLPI N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFBE3 SLPI 20110513 rna interference,inhibition western blot,quantitative reverse transcription pcr miRSponge
URS0000237AF9 SLPI 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001EFBE3 SLPI 20110513 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS0000355E82 SLPI 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A SLPI 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 SLPI 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 SLPI 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 SLPI 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 SLPI 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6479 SLPI 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000016C318 SLPI 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SLPI CTSL 25361965 interaction type N/A PTMCode2
CTSL SLPI 25361965 interaction type N/A PTMCode2
SLPI PLSCR1 25361965 interaction type N/A PTMCode2
PLSCR1 SLPI 25361965 interaction type N/A PTMCode2
PRSS1 SLPI 25361965 interaction type N/A PTMCode2
SLPI PRSS1 25361965 interaction type N/A PTMCode2
GRN SLPI 25361965 interaction type N/A PTMCode2
SLPI GRN 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HOXA1 SLPI 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGTA SLPI 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LAT SLPI 25348397 N/A two hybrid ComPPI
SLPI CTSB 11435427 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SLPI CTSS 11435427 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SLPI CTSL 11435427 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SLPI ELANE 10702419 14525934 18421166 24234451 25348397 N/A experimental interaction detection,x-ray crystallography,in vitro ComPPI,HPRD,IntAct
SLPI GRN 12526812 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SLPI KLK3 14525934 25348397 27898060 7539415 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SLPI PRSS2 14525934 25348397 27898060 8573092 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SLPI PLSCR1 10869562 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
SLPI FAM9B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLPI MAPK8IP2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SLPI NFKBIB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLPI CIB3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI MKRN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI CALN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI PIH1D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI EFEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI SGTB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI SMIM14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI UBQLN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLPI UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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