GENE：CXADR
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CXADR |
| FullNmae | CXADR Ig-like cell adhesion molecule |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2559 |
| EnsembleID | ENSG00000154639 |
| Uniprot | P78310 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CXADR | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CXADR | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CXADR | GO:0001618,GO:0001669,GO:0005178,GO:0005515,GO:0005576,GO:0005654,GO:0005737,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0005911,GO:0005912,GO:0005923,GO:0005923,GO:0007005,GO:0007157,GO:0007507,GO:0008013,GO:0008354,GO:0010669,GO:0014704,GO:0016323,GO:0016323,GO:0016327,GO:0030036,GO:0030054,GO:0030165,GO:0030175,GO:0030426,GO:0030593,GO:0032991,GO:0034109,GO:0043005,GO:0044297,GO:0045121,GO:0045216,GO:0046629,GO:0046718,GO:0050839,GO:0050839,GO:0055013,GO:0070633,GO:0071253,GO:0086067,GO:0086072,GO:0086082,GO:0098904 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CXADR | hsa:1525 | path:hsa03267 | Virion - Adenovirus - Homo sapiens (human) |
| CXADR | hsa:1525 | path:hsa05416 | Viral myocarditis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | CXADR | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CXADR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SNAI1 | CXADR | 10487759 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SNAI2 | CXADR | 10487759 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | CXADR | 22190856 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | CXADR | 22190856 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZEB1 | CXADR | 10487759 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZEB2 | CXADR | 10487759 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000ED600 | CXADR | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | CXADR | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001C3AC1 | CXADR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000148B91 | CXADR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NCOA1 | CXADR | 25348397 | N/A | physical interaction | ComPPI |
| NCOR1 | CXADR | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | CXADR | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | CXADR | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ELAVL1 | CXADR | 25348397 | N/A | physical interaction | ComPPI |
| LNX2 | CXADR | 15979067 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| LNX1 | CXADR | 12468544 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
| GRHPR | CXADR | 25348397 | N/A | physical interaction | ComPPI |
| CXADR | MAL | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| H1-5 | CXADR | 24234451 30021884 | physical association | cross-linking study | IntAct |