GENE：CXCL13
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CXCL13 |
| FullNmae | C-X-C motif chemokine ligand 13 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10639 |
| EnsembleID | ENSG00000156234 |
| Uniprot | O43927 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CXCL13 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CXCL13 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CXCL13 | GO:0002467,GO:0002518,GO:0002544,GO:0002920,GO:0005576,GO:0005576,GO:0005615,GO:0006954,GO:0006955,GO:0007166,GO:0007204,GO:0007267,GO:0008009,GO:0008009,GO:0008201,GO:0010820,GO:0017134,GO:0017134,GO:0030593,GO:0031724,GO:0031735,GO:0033625,GO:0033634,GO:0035754,GO:0035768,GO:0042742,GO:0045236,GO:0045765,GO:0048018,GO:0048248,GO:0061844,GO:0070098,GO:0071222,GO:0090630,GO:2000545 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CXCL13 | hsa:10563 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| CXCL13 | hsa:10563 | path:hsa04061 | Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human) |
| CXCL13 | hsa:10563 | path:hsa04062 | Chemokine signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CXCL13 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | CXCL13 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CXCL13 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CXCL13 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDKN1A | CXCL13 | 25348397 | N/A | physical interaction | ComPPI |
| CXCR3 | CXCL13 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| ACKR4 | CXCL13 | 10706668 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CCR10 | CXCL13 | 10706668 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CCL19 | CXCL13 | 14525934 15546958 16678487 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| CXCL13 | CCL21 | 14525934 15546958 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CXCL13 | EEF1G | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CXCL13 | FGF2 | 11708770 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CXCL13 | CXCR5 | 14525934 25348397 9463416 9486651 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| CXCL13 | A1BG | 25348397 | N/A | physical interaction,biochemical | ComPPI |
| CXCL13 | PF4V1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CXCL13 | CCL28 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CXCL13 | CCL2 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CCL4L1 | CXCL13 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CXCL13 | ACKR4 | 10706668 24218476 27898060 | N/A | N/A | OmniPath |
| CXCL13 | CXCR5 | 24218476 27898060 9463416 9486651 | stimulant | N/A | OmniPath |