Gene Information gene info

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GENE：ECT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ECT2
FullNmae epithelial cell transforming 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3155
EnsembleID ENSG00000114346
Uniprot Q9H8V3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ECT2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ECT2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ECT2 GO:0000281,GO:0000281,GO:0000902,GO:0005085,GO:0005085,GO:0005096,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005815,GO:0005829,GO:0005829,GO:0005911,GO:0005923,GO:0005938,GO:0007399,GO:0015031,GO:0016604,GO:0030154,GO:0030496,GO:0031267,GO:0032147,GO:0032154,GO:0032467,GO:0032467,GO:0035556,GO:0042307,GO:0042803,GO:0043065,GO:0043123,GO:0043547,GO:0043547,GO:0045666,GO:0045859,GO:0051056,GO:0051260,GO:0051988,GO:0070301,GO:0070830,GO:0071277,GO:0071479,GO:0072686,GO:0090630,GO:0090630,GO:0090630,GO:0097149,GO:2000431

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ECT2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CUX1 ECT2 19015243 21886810 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CUX1 ECT2 19015243 21886810 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F1 ECT2 19015243 21886810 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F4 ECT2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ECT2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ECT2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ECT2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ECT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ECT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ECT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ECT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ECT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ECT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 ECT2 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS0000028BB8 ECT2 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 ECT2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 ECT2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000016FF9C ECT2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001B341F ECT2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000003ABC4 ECT2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B7E30 ECT2 23601845 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000003E1A9 ECT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA ECT2 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCI ECT2 22135298 phosphorylation N/A PhosphoSite
CDK1 ECT2 22135298 phosphorylation N/A PhosphoSite
PARD6A ECT2 25361965 interaction type N/A PTMCode2
ECT2 PARD6A 25361965 interaction type N/A PTMCode2
ECT2 PLK1 25361965 interaction type N/A PTMCode2
PLK1 ECT2 25361965 interaction type N/A PTMCode2
ECT2 PARD3 25361965 interaction type N/A PTMCode2
PARD3 ECT2 25361965 interaction type N/A PTMCode2
ECT2 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ ECT2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CHCHD3 ECT2 25348397 N/A physical interaction ComPPI
HOXB9 ECT2 25348397 N/A physical interaction ComPPI
CDC5L ECT2 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPC ECT2 25348397 N/A physical interaction ComPPI
FHL3 ECT2 25348397 N/A physical interaction ComPPI
RPN1 ECT2 25348397 N/A physical interaction ComPPI
LDHB ECT2 25348397 N/A physical interaction ComPPI
LDHA ECT2 25348397 N/A physical interaction ComPPI
CFL1 ECT2 25348397 N/A physical interaction ComPPI
MCM6 ECT2 25348397 N/A physical interaction ComPPI
STRN ECT2 25348397 N/A physical interaction ComPPI
LARP1 ECT2 25348397 N/A physical interaction ComPPI
RACK1 ECT2 25348397 N/A physical interaction ComPPI
MAPK1 ECT2 25348397 N/A physical interaction ComPPI
RHOG ECT2 12376551 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RACGAP1 ECT2 14525934 18201571 19468300 19468302 22750944 24234451 25068414 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct,OmniPath
PIK3R1 ECT2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
NCK1 ECT2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 ECT2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
CTBP1 ECT2 25348397 N/A physical interaction ComPPI
CTBP2 ECT2 25348397 N/A physical interaction ComPPI
EIF5B ECT2 25348397 N/A physical interaction ComPPI
FLNA ECT2 25348397 N/A physical interaction ComPPI
KPNB1 ECT2 25348397 N/A physical interaction ComPPI
ABCD3 ECT2 25348397 N/A physical interaction ComPPI
YWHAB ECT2 25348397 N/A physical interaction ComPPI
YWHAZ ECT2 25348397 N/A physical interaction ComPPI
UBB ECT2 25348397 N/A physical interaction ComPPI
ESYT2 ECT2 25348397 N/A physical interaction ComPPI
CDH1 ECT2 22750944 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PCOLCE ECT2 25348397 N/A physical interaction ComPPI
CKAP4 ECT2 25348397 N/A physical interaction ComPPI
XRCC5 ECT2 25348397 N/A physical interaction ComPPI
RFC2 ECT2 25348397 N/A physical interaction ComPPI
PLK1 ECT2 14525934 16247472 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PSMA6 ECT2 25348397 N/A physical interaction ComPPI
PELP1 ECT2 25348397 N/A physical interaction ComPPI
PPP1CA ECT2 25348397 N/A physical interaction ComPPI
MYC ECT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
XRCC6 ECT2 25348397 N/A physical interaction ComPPI
F2RL2 ECT2 14525934 15254234 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CAPZA1 ECT2 25348397 N/A physical interaction ComPPI
PRKCZ ECT2 25348397 N/A physical interaction ComPPI
EIF6 ECT2 25348397 N/A physical interaction ComPPI
PPP2CA ECT2 25348397 N/A physical interaction ComPPI
PARD3 ECT2 25348397 N/A physical interaction ComPPI
PARD6A ECT2 14525934 15254234 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PDHB ECT2 25348397 N/A physical interaction ComPPI
RAD18 ECT2 25348397 N/A physical interaction ComPPI
ECT2 KLHL20 14525934 14668487 17395875 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
ECT2 ABR 25348397 N/A physical interaction ComPPI
ECT2 CD19 25348397 N/A physical interaction ComPPI
ECT2 CSTB 25348397 N/A physical interaction ComPPI
ECT2 EIF4A2 25348397 N/A physical interaction ComPPI
ECT2 MBD1 25348397 N/A physical interaction ComPPI
ECT2 MT2A 25348397 N/A physical interaction ComPPI
ECT2 MT-CO2 25348397 N/A physical interaction ComPPI
ECT2 RPS20 25348397 N/A physical interaction ComPPI
ECT2 ELOC 25348397 N/A physical interaction ComPPI
ECT2 VDAC2 25348397 N/A physical interaction ComPPI
ECT2 CHST10 25348397 N/A physical interaction ComPPI
ECT2 NPC2 25348397 N/A physical interaction ComPPI
ECT2 SNRNP200 25348397 N/A physical interaction ComPPI
ECT2 NOMO1 25348397 N/A physical interaction ComPPI
ECT2 ERAL1 25348397 N/A physical interaction ComPPI
ECT2 POMP 25348397 N/A physical interaction ComPPI
ECT2 CCDC91 25348397 N/A physical interaction ComPPI
ECT2 OTUB1 25348397 N/A physical interaction ComPPI
ECT2 FANCM 25348397 N/A physical interaction ComPPI
ECT2 SPATA22 25348397 N/A physical interaction ComPPI
ECT2 GGN 25348397 N/A physical interaction ComPPI
ECT2 OOSP2 25348397 N/A physical interaction ComPPI
ECT2 CRIPAK 25348397 N/A physical interaction ComPPI
ECT2 ALDH1B1 25348397 N/A physical interaction ComPPI
ECT2 ATP2A2 25348397 N/A physical interaction ComPPI
ECT2 CAPN1 25348397 N/A physical interaction ComPPI
ECT2 CAPN2 25348397 N/A physical interaction ComPPI
ECT2 CDK5 25348397 N/A physical interaction ComPPI
ECT2 AP3S1 25348397 N/A physical interaction ComPPI
ECT2 MRPL12 25348397 N/A physical interaction ComPPI
ECT2 SLC25A10 25348397 N/A physical interaction ComPPI
ECT2 CUX1 25348397 N/A physical interaction ComPPI
ECT2 CUX1 25348397 N/A physical interaction ComPPI
ECT2 CYC1 25348397 N/A physical interaction ComPPI
ECT2 DYNC1I2 25348397 N/A physical interaction ComPPI
ECT2 ACSL1 25348397 N/A physical interaction ComPPI
ECT2 GALK1 25348397 N/A physical interaction ComPPI
ECT2 MYO1D 25348397 N/A physical interaction ComPPI
ECT2 NUMA1 25348397 N/A physical interaction ComPPI
ECT2 NUP98 25348397 N/A physical interaction ComPPI
ECT2 PML 25348397 N/A physical interaction ComPPI
ECT2 PPM1G 25348397 N/A physical interaction ComPPI
ECT2 PSMD4 25348397 N/A physical interaction ComPPI
ECT2 RFC5 25348397 N/A physical interaction ComPPI
ECT2 SRSF1 25348397 N/A physical interaction ComPPI
ECT2 SLC1A5 25348397 N/A physical interaction ComPPI
ECT2 ELOA 25348397 N/A physical interaction ComPPI
ECT2 TCOF1 25348397 N/A physical interaction ComPPI
ECT2 TP53 25348397 N/A physical interaction ComPPI
ECT2 USP11 25348397 N/A physical interaction ComPPI
ECT2 USP9X 25348397 N/A physical interaction ComPPI
ECT2 ARID1A 25348397 N/A physical interaction ComPPI
ECT2 SLC25A11 25348397 N/A physical interaction ComPPI
ECT2 SUCLG2 25348397 N/A physical interaction ComPPI
ECT2 SUCLG1 25348397 N/A physical interaction ComPPI
ECT2 TRIP13 25348397 N/A physical interaction ComPPI
ECT2 GTF3C5 25348397 N/A physical interaction ComPPI
ECT2 NPEPPS 25348397 N/A physical interaction ComPPI
ECT2 RNF14 25348397 N/A physical interaction ComPPI
ECT2 NUP93 25348397 N/A physical interaction ComPPI
ECT2 UBE3C 25348397 N/A physical interaction ComPPI
ECT2 UNC13B 25348397 N/A physical interaction ComPPI
ECT2 MYL12B 25348397 N/A physical interaction ComPPI
ECT2 MYL12A 25348397 N/A physical interaction ComPPI
ECT2 AHCYL1 25348397 N/A physical interaction ComPPI
ECT2 CPSF4 25348397 N/A physical interaction ComPPI
ECT2 IMMT 25348397 N/A physical interaction ComPPI
ECT2 WDHD1 25348397 N/A physical interaction ComPPI
ECT2 STRAP 25348397 N/A physical interaction ComPPI
ECT2 XPOT 25348397 N/A physical interaction ComPPI
ECT2 COPE 25348397 N/A physical interaction ComPPI
ECT2 PHB2 25348397 N/A physical interaction ComPPI
ECT2 KDM1A 25348397 N/A physical interaction ComPPI
ECT2 TBC1D2B 25348397 N/A physical interaction ComPPI
ECT2 SIRT1 25348397 N/A physical interaction ComPPI
ECT2 NUP188 25348397 N/A physical interaction ComPPI
ECT2 PHGDH 25348397 N/A physical interaction ComPPI
ECT2 COPG2 25348397 N/A physical interaction ComPPI
ECT2 STOML2 25348397 N/A physical interaction ComPPI
ECT2 NUB1 25348397 N/A physical interaction ComPPI
ECT2 CPSF2 25348397 N/A physical interaction ComPPI
ECT2 DCAF16 25348397 N/A physical interaction ComPPI
ECT2 AGGF1 25348397 N/A physical interaction ComPPI
ECT2 PPP6R3 25348397 N/A physical interaction ComPPI
ECT2 IPO9 25348397 N/A physical interaction ComPPI
ECT2 CAND1 25348397 N/A physical interaction ComPPI
ECT2 CCDC47 25348397 N/A physical interaction ComPPI
ECT2 MICAL3 25348397 N/A physical interaction ComPPI
ECT2 UBE2O 25348397 N/A physical interaction ComPPI
ECT2 LPCAT1 25348397 N/A physical interaction ComPPI
ECT2 PUS1 25348397 N/A physical interaction ComPPI
ECT2 LAS1L 25348397 N/A physical interaction ComPPI
ECT2 SLFN11 25348397 N/A physical interaction ComPPI
ECT2 PPP1R18 25348397 N/A physical interaction ComPPI
ECT2 PGAM5 25348397 N/A physical interaction ComPPI
ECT2 SRPK2 25348397 N/A physical interaction ComPPI
ECT2 RPGRIP1L 24234451 25348397 26638075 association,physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ECT2 GPSM2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECT2 SAMD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECT2 RBM45 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECT2 SKA3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECT2 FOXM1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ECT2 ARIH1 25348397 N/A physical interaction ComPPI
ECT2 GKAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ECT2 NPHP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ECT2 KIF23 19468300 22750944 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ECT2 PLK4 20348415 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
ECT2 CTNNA1 22750944 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ECT2 LAMTOR5 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ECT2 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR5 ECT2 25348397 N/A physical interaction ComPPI
ILVBL ECT2 25348397 N/A physical interaction ComPPI
THAP11 ECT2 25348397 N/A physical interaction ComPPI
PELO ECT2 25348397 N/A physical interaction ComPPI
C2ORF42 ECT2 25348397 N/A physical interaction ComPPI
CDK1 ECT2 14525934 16247472 N/A experimental interaction detection HPRD
ECT2 RHOA 15774750 27898060 stimulant N/A OmniPath
PLK1 ECT2 16247472 17332740 18669648 27898060 stimulant N/A OmniPath
CDK1 ECT2 16170345 16247472 18669648 22172673 22898780 27898060 inhibition,stimulant N/A OmniPath
PRKCI ECT2 21189248 27898060 stimulant N/A OmniPath
ECT2 CDC42 15642749 27898060 stimulant N/A OmniPath

Visualization










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