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GENE：ELOVL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ELOVL1
FullNmae ELOVL fatty acid elongase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14418
EnsembleID ENSG00000066322
Uniprot Q9BW60

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ELOVL1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ELOVL1 GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0006636,GO:0009922,GO:0009922,GO:0009922,GO:0016020,GO:0019367,GO:0019367,GO:0030148,GO:0030148,GO:0034625,GO:0034625,GO:0034626,GO:0035338,GO:0036109,GO:0042761,GO:0042761,GO:0043651,GO:0046513,GO:0061436

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ELOVL1 hsa:64834 path:hsa00062 Fatty acid elongation - Homo sapiens (human)
ELOVL1 hsa:64834 path:hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human)
ELOVL1 hsa:64834 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ELOVL1 hsa:64834 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELOVL1 TLR9 17353931 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
AR ELOVL1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ELOVL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ELOVL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ELOVL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ELOVL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ELOVL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ELOVL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ELOVL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ELOVL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ELOVL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ELOVL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 ELOVL1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 ELOVL1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 ELOVL1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AD002 ELOVL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 ELOVL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE ELOVL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00006097A6 ELOVL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA ELOVL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC ELOVL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 ELOVL1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GLP1R ELOVL1 25348397 N/A physical interaction ComPPI
CERS2 ELOVL1 25348397 N/A physical interaction ComPPI
PSMD10 ELOVL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 ELOVL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NXF1 ELOVL1 25348397 N/A physical interaction ComPPI
ELOVL1 HSD17B12 25348397 N/A physical interaction ComPPI
ELOVL1 TECR 25348397 N/A physical interaction ComPPI
ELOVL1 MOV10 25348397 N/A physical interaction ComPPI
ELOVL1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TIMM44 ELOVL1 10352014 10367886 10913171 11273703 11564892 11733493 12032075 12677068 15719019 17881357 18426906 19036727 20007714 23864706 27898060 7809127 8530381 9155010 9171336 N/A N/A OmniPath
ELOVL1 TLR9 17353931 27898060 N/A N/A OmniPath

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