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GENE：ELOVL5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ELOVL5
FullNmae ELOVL fatty acid elongase 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21308
EnsembleID ENSG00000012660
Uniprot Q9NYP7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ELOVL5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ELOVL5 ferroptosis 40543851 Here, we deciphered hepatic protein corona on Fe2O3 NPs, and identified several lipogenic enzymes (FASN, FADS2, SCDb, ELOVL5, ACSL4, and ACSL1) associated with ferroptosis. retulator signature

Go Annotation:

GeneSymbol Go id
ELOVL5 GO:0005515,GO:0005783,GO:0005789,GO:0006636,GO:0009922,GO:0009922,GO:0009922,GO:0009922,GO:0016020,GO:0019367,GO:0030148,GO:0030425,GO:0034625,GO:0034625,GO:0034626,GO:0034626,GO:0035338,GO:0036109,GO:0042761,GO:0042761,GO:0043025,GO:0043651,GO:0045723,GO:0097447

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ELOVL5 hsa:60481 path:hsa00062 Fatty acid elongation - Homo sapiens (human)
ELOVL5 hsa:60481 path:hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human)
ELOVL5 hsa:60481 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ELOVL5 hsa:60481 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LYL1 ELOVL5 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ELOVL5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ELOVL5 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ELOVL5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ELOVL5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ELOVL5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ELOVL5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C ELOVL5 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ELOVL5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ELOVL5 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ELOVL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 ELOVL5 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 ELOVL5 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 ELOVL5 18668040 21572407 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000005481D ELOVL5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002D2333 ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B ELOVL5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000FFC8B ELOVL5 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002D0FC3 ELOVL5 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075E2C3 ELOVL5 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004818BD ELOVL5 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000195F5B ELOVL5 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 ELOVL5 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ELOVL5 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 ELOVL5 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA ELOVL5 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 ELOVL5 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031D186 ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 ELOVL5 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DPEP1 ELOVL5 25348397 N/A physical interaction ComPPI
SLC7A1 ELOVL5 25348397 N/A physical interaction ComPPI
UBC ELOVL5 25348397 N/A physical interaction ComPPI
SYNJ2BP ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
C2CD2L ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CERS2 ELOVL5 25348397 N/A physical interaction ComPPI
APLNR ELOVL5 25348397 N/A physical interaction ComPPI
ELAVL1 ELOVL5 25348397 N/A physical interaction ComPPI
GOSR2 ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMM17A ELOVL5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HMOX2 ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YIPF5 ELOVL5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC22A9 ELOVL5 25348397 N/A physical interaction ComPPI
THSD7A ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ELOVL5 SUCO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELOVL5 ROMO1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ELOVL5 TMEM243 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ELOVL5 SYS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HTR4 ELOVL5 24234451 28298427 physical association ubiquitin reconstruction IntAct

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