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GENE：EREG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EREG
FullNmae epiregulin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3443
EnsembleID ENSG00000124882
Uniprot O14944

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EREG mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EREG immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EREG autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EREG GO:0001525,GO:0001550,GO:0001556,GO:0001819,GO:0001819,GO:0005154,GO:0005154,GO:0005154,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005886,GO:0007143,GO:0007173,GO:0007173,GO:0007173,GO:0007267,GO:0008083,GO:0008284,GO:0008284,GO:0008284,GO:0008285,GO:0009299,GO:0009653,GO:0009887,GO:0019221,GO:0030216,GO:0030297,GO:0030669,GO:0030728,GO:0032755,GO:0038134,GO:0038135,GO:0038138,GO:0042060,GO:0042327,GO:0042700,GO:0043434,GO:0043616,GO:0045089,GO:0045740,GO:0045740,GO:0045840,GO:0045840,GO:0045860,GO:0045892,GO:0048018,GO:0048146,GO:0048160,GO:0048661,GO:0050680,GO:0051151,GO:0051781

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EREG hsa:2069 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
EREG hsa:2069 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
EREG hsa:2069 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
EREG hsa:2069 path:hsa05210 Colorectal cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EREG EGFR 20430953 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR EREG 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 EREG 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EREG 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 EREG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
KDM2A EREG 23074094 trascriptional regulation,stimulation inferred by curator TFlink
NFIL3 EREG 1620116 trascriptional regulation,stimulation inferred by curator TFlink
WT1 EREG 17430890 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 EREG 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000016FD1A EREG 22815788 23446348 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,clip TarBase
URS00000DDD35 EREG 22815788 25416803 26701625 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,clip TarBase
URS00002F3336 EREG 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 EREG 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000302909 EREG 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 EREG 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 EREG 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 EREG 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000600E6 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000315338 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002C0FCB EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002075FA EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006FDD4 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000042E1F EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B3783 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BD1DE EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000076995 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000272A3D EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C11BC EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000251D0B EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027080C EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000610EFA EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000018E72A EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075BC91 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000475586 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000031602A EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000078918 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003883FE EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037D7E5 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000298BA3 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000195F5B EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004BC299 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000012930C EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000043D2C1 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000031BC7D EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075BDAA EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000202460 EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004E008F EREG 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EREG EGFR 25361965 interaction type N/A PTMCode2
EGFR EREG 25361965 interaction type N/A PTMCode2
EREG ERBB4 25361965 interaction type N/A PTMCode2
ERBB4 EREG 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RAB4A EREG 25348397 N/A physical interaction ComPPI
CXCL9 EREG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OLFM4 EREG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ERBB4 EREG 14525934 25348397 9419975 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EGFR EREG 14525934 25348397 9419975 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EREG TMX4 25348397 N/A physical interaction ComPPI
EREG LGALS1 25348397 N/A physical interaction ComPPI
EREG NINJ2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EREG EGFR 20513444 27898060 9419975 stimulant N/A OmniPath
EREG ERBB4 16829981 22891299 27898060 9419975 stimulant N/A OmniPath
EREG ERBB3 16829981 22891299 27898060 stimulant N/A OmniPath

Visualization










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