GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
INF2 |
FullNmae |
inverted formin 2 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:23791 |
EnsembleID |
ENSG00000203485 |
Uniprot |
Q27J81 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
INF2 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
INF2 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
INF2 |
disulfidptosis |
39146597 |
Previous studies have identified 15 essential genes (FLNA, FLNB, MYH9, TLN1, ACTB, MYL6, MYH10, CAPZB, DSTN, IQGAP1, ACTN4, PDLIM1, CD2AP, INF2, SLC7A11) associated with disulfidptosis. |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
INF2 |
GO:0003779,GO:0005515,GO:0005884,GO:0030041,GO:0031267,GO:0048471,GO:0090140 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
E2F4 |
INF2 |
17531812
18971253
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array,inferred by curator |
TFlink |
ETS1 |
INF2 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
GATA1 |
INF2 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
GATA2 |
INF2 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
TFAP2C |
INF2 |
20629094
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TRIM28 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ZNF263 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00001A6D0C |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003804D8 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000149319 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000054DF42 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000C48FA |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004AD450 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000247AC6 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CHEK1 |
INF2 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PPP1CC |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
TOMM22 |
INF2 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
VCP |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
PPP1CB |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
CRK |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBE2R2 |
INF2 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
FLNA |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
CANX |
INF2 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
PFN2 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
PPP1CA |
INF2 |
24234451
25348397
25593058
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
CSNK2A1 |
INF2 |
25348397
|
N/A |
physical interaction,protein kinase assay |
ComPPI |
HNRNPL |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
IQGAP1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
MYO18A |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM25 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
GAK |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
TOMM20 |
INF2 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
SYNPO |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ANLN |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
ACTR2 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
IFI16 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
MYH9 |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
MYO1C |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
CD55 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ADD1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
LIMA1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
DBN1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
MYH11 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
NXF1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
GCN1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
CAPZA2 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
MOV10 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TMOD3 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
RSPRY1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
MYO5C |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
INF2 |
MYO19 |
25348397
|
N/A |
physical interaction |
ComPPI |
INF2 |
CFAP97 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
BDKRB2 |
INF2 |
24234451
28298427
|
physical association |
ubiquitin reconstruction |
IntAct |
Visualization