GENE:IRAK1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | IRAK1 |
FullNmae | interleukin 1 receptor associated kinase 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:6112 |
EnsembleID | ENSG00000184216 |
Uniprot | P51617 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
IRAK1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
IRAK1 | apoptosis | 26068967 | Genetic knock-down of IRAK1 led to apoptosis, cell cycle disruption, diminished proliferation and reversal of corticosteroid resistance in T-ALL cell lines. | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
IRAK1 | GO:0001959,GO:0002224,GO:0002755,GO:0004672,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004704,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005811,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0006468,GO:0007250,GO:0007254,GO:0008063,GO:0009986,GO:0010008,GO:0016301,GO:0019901,GO:0031072,GO:0031663,GO:0032088,GO:0032481,GO:0032496,GO:0032991,GO:0034134,GO:0034134,GO:0034142,GO:0034162,GO:0034605,GO:0035556,GO:0038172,GO:0042802,GO:0042803,GO:0043123,GO:0043123,GO:0043123,GO:0043406,GO:0045087,GO:0046777,GO:0046982,GO:0048661,GO:0051092,GO:0051092,GO:0060337,GO:0070498,GO:0070498,GO:0070498,GO:0070555,GO:0071222,GO:0071456,GO:0106310,GO:1901224,GO:1904996 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
IRAK1 | hsa:3654 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa04064 | NF-kappa B signaling pathway - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa04620 | Toll-like receptor signaling pathway - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa04722 | Neurotrophin signaling pathway - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa04936 | Alcoholic liver disease - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05130 | Pathogenic Escherichia coli infection - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05132 | Salmonella infection - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05133 | Pertussis - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05135 | Yersinia infection - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05140 | Leishmaniasis - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05142 | Chagas disease - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05145 | Toxoplasmosis - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05152 | Tuberculosis - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05161 | Hepatitis B - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05162 | Measles - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05168 | Herpes simplex virus 1 infection - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05169 | Epstein-Barr virus infection - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05171 | Coronavirus disease - COVID-19 - Homo sapiens (human) |
IRAK1 | hsa:3654 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
IL1R1 | IRAK1 | 11274345 12242293 12609980 12620219 12682231 12738796 14625308 14660645 15125833 15866876 15905496 16252010 16286016 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23180781 23331499 23681101 23811849 26192618 9374458 9430229 | interaction type,stimulation,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB,SignaLink |
MYD88 | IRAK1 | 10679398 11274345 11592085 11976320 12538665 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16024789 16252010 16878026 16951367 17228323 17276401 17704786 17785432 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 21903422 23070005 23180781 23681101 23811849 26192618 26885855 27048821 27066895 9469432 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
TRAF6 | IRAK1 | 10383454 10920205 11259596 11274345 11960013 12150927 12620219 12738796 14660645 15125833 15894263 16024789 16252010 16878026 16951367 17197697 17704786 17785432 17948050 18264787 18758450 18855897 18922473 18977329 19161412 19716405 21220427 21614932 22033459 23070005 23180781 23681101 23811849 26192618 8837778 9374458 | interaction type,physical association | anti tag coimmunoprecipitation,two hybrid | ACSN,InnateDB |
IL1RAP | IRAK1 | 11274345 12620219 12682231 12738796 14660645 15044087 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23180781 23681101 23811849 26192618 9371760 9374458 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
IRAK4 | IRAK1 | 10679398 11274345 11592085 11960013 12538665 12620219 12682231 12738796 12860405 14504095 14660645 14662834 15084582 15099563 15125833 15802534 16252010 16878026 17276401 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 21903422 23070005 23180781 23681101 23811849 26192618 26885855 27048821 27066895 9469432 | interaction type,phosphorylation reaction,physical association | anti tag coimmunoprecipitation,two hybrid,in-gel kinase assay | ACSN,InnateDB |
CD14 | IRAK1 | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
IRAK2 | IRAK1 | 10383454 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16024789 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 21903422 23180781 23508573 23681101 23811849 24973222 26192618 9743347 | interaction type,phosphorylation reaction,physical association | anti tag coimmunoprecipitation,in-gel kinase assay,Split renilla luciferase complementation | ACSN,InnateDB |
LY96 | IRAK1 | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
TIRAP | IRAK1 | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 21903422 23180781 23508573 23681101 23811849 26192618 9743347 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
IL18 | IRAK1 | 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26192618 26885855 27048821 27066895 9469432 | interaction type | N/A | ACSN |
IL18R1 | IRAK1 | 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26192618 26885855 27048821 27066895 9469432 | interaction type | N/A | ACSN |
IL18RAP | IRAK1 | 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26192618 26885855 27048821 27066895 9469432 | interaction type | N/A | ACSN |
IRAK1 | MAP2K6 | 11274345 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26192618 | interaction type | N/A | ACSN |
TRAF4 | IRAK1 | 16052631 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IKBKB | IRAK1 | 11096118 18180283 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | IRAK1BP1 | 11096118 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PELI1 | IRAK1 | 16951688 17997719 23180781 26082489 | phosphorylation reaction,physical association | anti tag coimmunoprecipitation,protein kinase assay | InnateDB |
IRAK1 | IRAK1 | 11259596 11751856 12054681 12242293 12496252 14625308 15647277 16024789 23180781 26467481 8837778 | phosphorylation reaction,bind,physical association,up-regulates activity | affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid,in-gel kinase assay | InnateDB,Signor |
TOLLIP | IRAK1 | 11751856 15388348 16024789 17276401 19716405 21903422 23180781 | phosphorylation reaction,physical association | anti tag coimmunoprecipitation,in-gel kinase assay | InnateDB |
RIPK2 | IRAK1 | 15691841 16824733 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TLR4 | IRAK1 | 23180781 9625770 | physical association | anti tag coimmunoprecipitation | InnateDB |
PELI2 | IRAK1 | 12860405 19081057 23180781 | phosphorylation reaction,physical association | anti tag coimmunoprecipitation,pull down,in-gel kinase assay | InnateDB |
IRAK3 | IRAK1 | 10383454 21903422 23180781 | phosphorylation reaction,physical association | anti tag coimmunoprecipitation,in-gel kinase assay | InnateDB |
PRKCI | IRAK1 | 14684752 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | NGFR | 14684752 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | PRKCI | 14684752 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SUMO1 | IRAK1 | 16690127 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRF7 | IRAK1 | 15767370 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NLRP12 | IRAK1 | 16203735 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | MAP3K7 | 12242293 17197697 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TAB2 | 11518704 12242293 18180283 19675569 21071413 23180781 23331499 | stimulation,physical association | anti tag coimmunoprecipitation | InnateDB,SignaLink,SignaLink |
HRAS | IRAK1 | 11744690 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
BTK | IRAK1 | 12724322 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SIGIRR | IRAK1 | 12925853 15866876 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TLR2 | IRAK1 | 10395652 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ITGAM | IRAK1 | 11701612 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
AKT1 | IRAK1 | 11976320 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
HSP90AA1 | IRAK1 | 15647277 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
STIP1 | IRAK1 | 15647277 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
HSPA4 | IRAK1 | 15647277 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
CDC37 | IRAK1 | 15647277 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
HSPA8 | IRAK1 | 15647277 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
STAT3 | IRAK1 | 15465816 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | IL10 | 15465816 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TLR5 | 11953430 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PRKCZ | IRAK1 | 11937546 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
CAV1 | IRAK1 | 16107720 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SQSTM1 | IRAK1 | 10747026 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TAB2 | IRAK1 | 11259596 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TRIP6 | IRAK1 | 15657077 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TRAF3 | IRAK1 | 16306936 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAPK14 | IRAK1 | 15388348 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NFKBIA | IRAK1 | 18276832 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
FADD | IRAK1 | 17785432 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | CHUK | 18180283 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PELI3 | IRAK1 | 17997719 19081057 23180781 | phosphorylation reaction,physical association | pull down,protein kinase assay | InnateDB |
RCAN1 | IRAK1 | 19716405 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
VASP | IRAK1 | 20044140 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TNFAIP3 | 21220427 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TNFRSF13B | 20676093 23180781 | physical association | pull down | InnateDB |
PIN1 | IRAK1 | 21743479 23180781 | physical association | anti tag coimmunoprecipitation,pull down | InnateDB |
IRAK1 | IRAK2 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | IQSEC1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | YTHDC2 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | RHOT1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TOMM70 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | SNRNP200 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | CCDC47 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | MAGED1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | PJA1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | PPP3CB | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TRIM32 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TARDBP | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | BAG3 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | COQ8A | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRF4 | IRAK1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SARM1 | IRAK1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
STING1 | IRAK1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
UNC93B1 | IRAK1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
UNC5CL | IRAK1 | 22158417 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IKBKG | IRAK1 | 11583588 17997719 18180283 21220427 23180781 | physical association | anti tag coimmunoprecipitation,pull down | InnateDB |
IRAK1 | IRAK4 | 15905496 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IRAK1 | TAB1 | 11518704 23331499 | stimulation | N/A | SignaLink,SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
FADD | IRAK1 | 20005715 | interaction type | N/A | PSP |
TAB2 | IRAK1 | 11518704 18180283 18988627 20005715 | interaction type | N/A | PSP,SignaLink |
SQSTM1 | IRAK1 | 12034707 18988627 20005715 | interaction type | N/A | PSP,SignaLink |
TIFA | IRAK1 | 20005715 | interaction type | N/A | PSP |
TOLLIP | IRAK1 | 10854325 18988627 20005715 | interaction type | N/A | PSP,SignaLink |
FADD | IRAK1 | 11828002 18988627 20005715 20005715 | N/A | N/A | SignaLink |
TIFA | IRAK1 | 12566447 18988627 20005715 20005715 | N/A | N/A | SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | IRAK1 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | IRAK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | IRAK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | IRAK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | IRAK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | IRAK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | IRAK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00001EFBE3 | IRAK1 | 16885212 18504431 19918258 20061417 20110513 20542134 21178010 21632853 22593544 \N | rna interference,inhibition | array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS000050CCE0 | IRAK1 | 16885212 | rna interference,inhibition | array technology,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS00001EFBE3 | IRAK1 | 16885212 18504431 18759964 18927107 19596990 19918258 20061417 20110513 20542134 21178010 21632853 22593544 22992343 23018031 23680172 23952003 24107356 24867582 25416803 25623956 25805648 25889446 26151128 27636999 27922090 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | miR2Disease,TarBase |
URS000050CCE0 | IRAK1 | 16885212 23680172 25416803 25771167 27533309 | mrna cleavage,inhibition | array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS00000F31F4 | IRAK1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | IRAK1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00002971AB | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000EC1BE | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000007A060 | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000DDD35 | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000AA464 | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000BE495 | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00005FDE70 | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000028BB8 | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000153377 | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00002075FA | IRAK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000009262D | IRAK1 | 23633945 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS00001E0AEA | IRAK1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
IRAK1 | PELI1 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
IRAK1 | IRAK1 | 22135298 | phosphorylation | N/A | PhosphoSite |
IRAK1 | PELI2 | 22135298 | phosphorylation | N/A | PhosphoSite |
IRAK1 | STAT3 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
AKT1 | IRAK1 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
IRAK4 | IRAK1 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
IRAK1 | CHUK | 25361965 | interaction type | N/A | PTMCode2 |
CHUK | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | JUN | 25361965 | interaction type | N/A | PTMCode2 |
JUN | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | PRKCZ | 25361965 | interaction type | N/A | PTMCode2 |
PRKCZ | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | MYD88 | 25361965 | interaction type | N/A | PTMCode2 |
MYD88 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
PELI3 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | PELI3 | 25361965 | interaction type | N/A | PTMCode2 |
RIPK2 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | RIPK2 | 25361965 | interaction type | N/A | PTMCode2 |
TOLLIP | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | TOLLIP | 25361965 | interaction type | N/A | PTMCode2 |
IL1R1 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | IL1R1 | 25361965 | interaction type | N/A | PTMCode2 |
STAT3 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
PRKCI | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | PRKCI | 25361965 | interaction type | N/A | PTMCode2 |
IRF7 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | IRF7 | 25361965 | interaction type | N/A | PTMCode2 |
IL1RAP | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | IL1RAP | 25361965 | interaction type | N/A | PTMCode2 |
PELI1 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
NLRP12 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | NLRP12 | 25361965 | interaction type | N/A | PTMCode2 |
BCL10 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | BCL10 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | AKT1 | 25361965 | interaction type | N/A | PTMCode2 |
MAPK14 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | MAPK14 | 25361965 | interaction type | N/A | PTMCode2 |
TRAF6 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | TRAF6 | 25361965 | interaction type | N/A | PTMCode2 |
HSP90AA1 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | HSP90AA1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | IRAK4 | 25361965 | interaction type | N/A | PTMCode2 |
FADD | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | FADD | 25361965 | interaction type | N/A | PTMCode2 |
TRAF4 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | TRAF4 | 25361965 | interaction type | N/A | PTMCode2 |
TIFA | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | TIFA | 25361965 | interaction type | N/A | PTMCode2 |
SIGIRR | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | SIGIRR | 25361965 | interaction type | N/A | PTMCode2 |
TNFRSF1A | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | TNFRSF1A | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1BP1 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | IRAK1BP1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK3 | IRAK1 | 25361965 | interaction type | N/A | PTMCode2 |
IRAK1 | IRAK3 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PIN1 | IRAK1 | 21743479 24234451 25348397 | physical association | anti bait coimmunoprecipitation,nuclear magnetic resonance,pull down | ComPPI,IntAct |
HSPA8 | IRAK1 | 24234451 25348397 29568061 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
VASP | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
BAG3 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
ATP5F1B | IRAK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TNFAIP3 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
STAT1 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
EMD | IRAK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TRAF6 | IRAK1 | 10346818 10383454 11518704 12242293 14525934 24234451 25348397 8837778 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
LMNA | IRAK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TRIM32 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
OPTN | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
TIFA | IRAK1 | 12566447 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
HRAS | IRAK1 | 11744690 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
BTK | IRAK1 | 12724322 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
PRKCD | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
JUN | IRAK1 | 10346818 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
SUMO1 | IRAK1 | 14525934 16690127 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
MAPK14 | IRAK1 | 10346818 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
IRF4 | IRAK1 | 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CUL3 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
IL1RAP | IRAK1 | 14525934 25348397 9371760 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
UBC | IRAK1 | 16884718 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
HSP90AA1 | IRAK1 | 14525934 15647277 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
CDH1 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
BTRC | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
CAV1 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
STIP1 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
IKBKB | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
TIRAP | IRAK1 | 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MYC | IRAK1 | 17314511 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
DNAJA3 | IRAK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
ST13 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
PRKCZ | IRAK1 | 11937546 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
MAPK6 | IRAK1 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
PPP2CA | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | SQSTM1 | 12034707 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | MYD88 | 10383454 10854325 14525934 17567694 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | FADD | 11828002 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
IRAK1 | TLR2 | 10395652 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | IRAK2 | 10383454 14525934 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | IRAK3 | 10383454 14525934 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | TAB2 | 11518704 14525934 18180283 19675569 24234451 25348397 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | TOLLIP | 10854325 14525934 21903422 24234451 25348397 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | IRAK4 | 11960013 12860405 14525934 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | SIGIRR | 12925853 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | TICAM2 | 12721283 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
IRAK1 | PELI3 | 12874243 14525934 16884718 17675297 18326498 24234451 25348397 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | PELI2 | 12370331 12860405 14525934 16884718 17675297 18326498 19081057 24234451 25348397 | physical association | anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,protein kinase assay,in vitro,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | STAT3 | 14525934 15465816 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
IRAK1 | ITGAM | 11701612 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | TRAF4 | 14525934 16052631 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | MAP3K7 | 12242293 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | TLR4 | 14525934 25348397 9625770 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | RIPK2 | 14525934 15691841 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
IRAK1 | IRF7 | 14525934 15767370 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
IRAK1 | NLRP12 | 14525934 16203735 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
IRAK1 | MBP | 10346818 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
IRAK1 | AKT1 | 11976320 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
IRAK1 | CHUK | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | IKBKG | 14525934 18180283 23104095 24234451 25348397 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction | ComPPI,HPRD,IntAct |
IRAK1 | CAMKK2 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | CLN3 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | TLR9 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | COQ8A | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | CCDC47 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | IQSEC1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | MAGED1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | PJA1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | PPP3CB | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | RHOT1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | SNRNP200 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | TARDBP | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | TOMM70 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | YTHDC2 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | SARM1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | STING1 | 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | UNC93B1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | RCAN1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | IL1R1 | 25348397 | N/A | coimmunoprecipitation,experimental interaction detection,physical interaction,physical interaction | ComPPI |
IRAK1 | FBXW11 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | CUL1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | CDC37 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | HSPA4 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | H3-4 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | ST13P4 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | PINK1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | IL1RL1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | TNFRSF13B | 20676093 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
IRAK1 | MMS19 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | MAP3K3 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | SASH1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | RNF31 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | CCDC8 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | AIFM1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | ATP1A1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | BAG2 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | CCT2 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | CCT3 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | CCT4 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | CCT5 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | CCT6A | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | CCT7 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | CCT8 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | DNAJA1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | DNAJA2 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | EEF2 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | HLA-A | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | HSPB1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | IMMT | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | RCN1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | SEC16A | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | MRPL12 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | SLC25A10 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | SLC25A13 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | SLC2A1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | SLC7A5 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | SLC7A5P1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | STUB1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | TIMM50 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
IRAK1 | SSX2IP | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
IRAK1 | CEP104 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
IRAK1 | STIL | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
IRAK1 | XPO1 | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | EGFR | 25348397 | N/A | physical interaction | ComPPI |
IRAK1 | TAB1 | 14743216 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
IRAK1 | RIPK4 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
TCP1 | IRAK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PRKCI | IRAK1 | 14525934 14684752 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
IRAK1BP1 | IRAK1 | 11096118 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
HNRNPF | IRAK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
BCL10 | IRAK1 | 25348397 | N/A | physical interaction | ComPPI |
CALU | IRAK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PELI1 | IRAK1 | 12496252 14525934 16884718 17675297 19264966 24234451 25348397 | phosphorylation reaction,association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,phosphorylation reaction,physical interaction,protein kinase assay | ComPPI,HPRD,IntAct |
HSCB | IRAK1 | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
IRAK1 | NTRK3 | 12034707 14525934 | N/A | experimental interaction detection | HPRD |
IRAK1 | IRAK1 | 10383454 11960013 12138165 14525934 24234451 | physical association | anti tag coimmunoprecipitation,experimental interaction detection | HPRD,IntAct |
MKI67 | IRAK1 | 24234451 26949251 | association | anti tag coimmunoprecipitation | IntAct |
IRAK1 | HSPA8 | 15647277 27898060 | N/A | N/A | OmniPath |
IRAK1 | VASP | 20044140 27898060 | N/A | N/A | OmniPath |
IRAK1 | CAV1 | 16107720 27898060 | N/A | N/A | OmniPath |
MAP3K7 | IRAK1 | 12242293 17197697 19026643 23244239 27898060 | N/A | N/A | OmniPath |
IRAK1 | TNFAIP3 | 21220427 27898060 | N/A | N/A | OmniPath |
IRAK1 | CHUK | 11096118 18180283 27898060 | stimulant | N/A | OmniPath |
IRAK1 | RIPK2 | 15691841 16824733 27898060 | N/A | N/A | OmniPath |
FADD | IRAK1 | 11828002 17785432 27898060 | N/A | N/A | OmniPath |
HRAS | IRAK1 | 11744690 27898060 | N/A | N/A | OmniPath |
SOCS1 | IRAK1 | 12433373 27898060 | inhibition | N/A | OmniPath |
PIN1 | IRAK1 | 21743479 27898060 | N/A | N/A | OmniPath |
IRAK1 | TRAF6 | 10346818 10383454 10920205 11259596 11287640 11397809 11518704 11960013 12140561 12242293 12496252 12566447 14625308 15894263 16024789 16831874 16951367 16951688 17197697 17785432 17785851 18056395 18234474 18347055 19166926 19716405 20043910 21220427 21460221 22033459 22447928 23244239 23381138 24434549 24735611 27898060 8837778 9374458 | stimulant | N/A | OmniPath |
TRAF6 | IRAK1 | 10346818 10383454 10920205 11259596 11287640 11397809 11518704 11960013 12140561 12242293 12496252 12566447 14625308 15894263 16024789 16831874 16951367 16951688 17197697 17785432 17785851 18056395 18234474 18347055 19166926 19716405 20043910 21220427 21460221 22033459 22447928 23244239 23381138 24434549 24735611 27898060 8837778 9374458 | stimulant | N/A | OmniPath |
AKT1 | IRAK1 | 11976320 27898060 | inhibition | N/A | OmniPath |
IRAK1 | AKT1 | 11976320 27898060 | N/A | N/A | OmniPath |
TLR4 | IRAK1 | 17635639 27898060 9625770 | N/A | N/A | OmniPath |
IRAK1 | TLR5 | 11953430 27898060 | N/A | N/A | OmniPath |
IKBKG | IRAK1 | 11583588 17997719 18180283 18347055 21220427 23104095 23986494 24735611 27898060 | N/A | N/A | OmniPath |
IRAK1 | MYD88 | 10217414 10383454 10811644 10854325 11544529 11960013 11976320 12034707 12360211 12538665 16024789 16461741 16951367 16951688 17228323 17276401 17510469 17548806 17567694 17785432 17920759 18524972 19679662 21179087 21743479 21903422 22011580 27898060 9430229 | N/A | N/A | OmniPath |
MYD88 | IRAK1 | 10217414 10383454 10811644 10854325 11544529 11960013 11976320 12034707 12360211 12538665 16024789 16461741 16951367 16951688 17228323 17276401 17510469 17548806 17567694 17785432 17920759 18524972 19679662 19775907 21179087 21743479 21903422 22011580 27898060 9430229 | stimulant | N/A | OmniPath |
TLR2 | IRAK1 | 10395652 27898060 | N/A | N/A | OmniPath |
IRAK1 | TLR2 | 10395652 27898060 | stimulant | N/A | OmniPath |
IRAK1 | MAGED1 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | BTK | 12724322 27898060 | N/A | N/A | OmniPath |
BTK | IRAK1 | 12724322 27898060 | N/A | N/A | OmniPath |
MAPK14 | IRAK1 | 10346818 15388348 27898060 | N/A | N/A | OmniPath |
IRAK1 | PRKCZ | 11937546 27898060 | N/A | N/A | OmniPath |
IRAK1 | SUMO1 | 16690127 27898060 | N/A | N/A | OmniPath |
IRAK1 | TAB2 | 11259596 11518704 12242293 18180283 19675569 23986494 24735611 27898060 | stimulant | N/A | OmniPath |
TAB2 | IRAK1 | 11259596 11518704 12242293 18180283 19675569 23986494 24735611 27898060 | N/A | N/A | OmniPath |
IRAK1 | IRF7 | 15767370 17457343 21903422 27898060 | stimulant | N/A | OmniPath |
IRF7 | IRAK1 | 15767370 21903422 27898060 | N/A | N/A | OmniPath |
IL1R1 | IRAK1 | 12242293 12609980 14625308 15866876 15905496 16024789 16286016 22904187 24735611 27898060 8599092 9374458 9426216 9430229 | stimulant | N/A | OmniPath |
ITGAM | IRAK1 | 11701612 27898060 | N/A | N/A | OmniPath |
IRAK1 | ITGAM | 11701612 27898060 | N/A | N/A | OmniPath |
IRAK1 | TRAF4 | 16052631 27898060 | N/A | N/A | OmniPath |
TRAF4 | IRAK1 | 16052631 27898060 | N/A | N/A | OmniPath |
IRAK1 | PRKCI | 14684752 27898060 | N/A | N/A | OmniPath |
RCAN1 | IRAK1 | 19716405 27898060 | N/A | N/A | OmniPath |
SQSTM1 | IRAK1 | 10747026 12034707 27898060 | stimulant | N/A | OmniPath |
IRAK1 | STAT3 | 15465816 27898060 | stimulant | N/A | OmniPath |
IRAK1 | TAB1 | 11518704 14743216 27898060 | stimulant | N/A | OmniPath |
TIRAP | IRAK1 | 21903422 27898060 | N/A | N/A | OmniPath |
TRAF3 | IRAK1 | 16306936 27898060 | N/A | N/A | OmniPath |
IRAK1 | IRAK4 | 11960013 12538665 12860405 14751757 15084582 15292196 15905496 16024789 16951688 17276401 17785851 18221795 18524972 19166926 21903422 24735611 27898060 | N/A | N/A | OmniPath |
IRAK4 | IRAK1 | 11960013 11976320 12538665 12860405 14751757 15084582 15292196 15905496 16024789 16951688 17276401 17785851 18221795 18252867 18524972 19166926 19775907 21903422 24735611 27898060 | stimulant | N/A | OmniPath |
IRAK1 | IKBKB | 11096118 18180283 27898060 | stimulant | N/A | OmniPath |
IRAK1 | IRAK1BP1 | 11096118 27898060 | N/A | N/A | OmniPath |
IRAK1 | TARDBP | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | CCDC47 | 21903422 27898060 | N/A | N/A | OmniPath |
PELI2 | IRAK1 | 12370331 12860405 15917247 16884718 17675297 17997719 18326498 19081057 25027698 27898060 | stimulant | N/A | OmniPath |
IL1RAP | IRAK1 | 15044087 24735611 27898060 9371760 9374458 | N/A | N/A | OmniPath |
IRAK1 | PELI3 | 12874243 15917247 16884718 17675297 17997719 18326498 19081057 25027698 27898060 | stimulant | N/A | OmniPath |
PELI3 | IRAK1 | 12874243 15917247 16884718 17675297 17997719 18326498 19081057 25027698 27898060 | stimulant | N/A | OmniPath |
TNFRSF13B | IRAK1 | 20676093 27898060 | N/A | N/A | OmniPath |
IRAK1 | RHOT1 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | STIP1 | 15647277 27898060 | N/A | N/A | OmniPath |
UNC5CL | IRAK1 | 22158417 27898060 | N/A | N/A | OmniPath |
IRAK1 | PJA1 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | YTHDC2 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | IQSEC1 | 21903422 27898060 | N/A | N/A | OmniPath |
UNC93B1 | IRAK1 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | BAG3 | 21903422 27898060 | N/A | N/A | OmniPath |
IRF4 | IRAK1 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | NLRP12 | 16203735 27898060 | N/A | N/A | OmniPath |
TRIP6 | IRAK1 | 15657077 27898060 | N/A | N/A | OmniPath |
IRAK1 | HSPA4 | 15647277 27898060 | N/A | N/A | OmniPath |
IRAK1 | IRAK3 | 10383454 12138165 19166926 21903422 27898060 | stimulant | N/A | OmniPath |
IRAK3 | IRAK1 | 10383454 12138165 19166926 21903422 27898060 | inhibition | N/A | OmniPath |
IRAK1 | SNRNP200 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | COQ8A | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | PELI1 | 12496252 15917247 16884718 16951688 17675297 17997719 19081057 19264966 21204785 26082489 27898060 | stimulant | N/A | OmniPath |
PELI1 | IRAK1 | 12496252 15917247 16884718 16951688 17675297 17997719 19081057 19264966 21204785 26082489 27898060 | stimulant | N/A | OmniPath |
IRAK1 | PPP3CB | 21903422 27898060 | N/A | N/A | OmniPath |
SARM1 | IRAK1 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | TRIM32 | 21903422 27898060 | N/A | N/A | OmniPath |
STING1 | IRAK1 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK2 | IRAK1 | 10383454 12138165 16024789 21903422 24973222 27898060 | N/A | N/A | OmniPath |
IRAK1 | IRAK2 | 10383454 12138165 16024789 21903422 24973222 27898060 | stimulant | N/A | OmniPath |
IRAK1 | TOLLIP | 10854325 11397809 11751856 14751757 15388348 16024789 16107720 17113392 17276401 17635639 19716405 21903422 23244239 26673132 27898060 | N/A | N/A | OmniPath |
TOLLIP | IRAK1 | 10854325 11397809 11751856 14751757 15388348 16024789 16107720 17113392 17276401 17635639 19716405 21903422 23244239 26673132 27898060 | inhibition,stimulant | N/A | OmniPath |
IRAK1 | TOMM70 | 21903422 27898060 | N/A | N/A | OmniPath |
IRAK1 | SIGIRR | 12925853 15866876 27898060 | N/A | N/A | OmniPath |
SIGIRR | IRAK1 | 12925853 15866876 27898060 | N/A | N/A | OmniPath |
IRAK1 | CDC37 | 15647277 27898060 | N/A | N/A | OmniPath |
CDC37 | IRAK1 | 15647277 27898060 | N/A | N/A | OmniPath |