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GENE：LAMA4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LAMA4
FullNmae laminin subunit alpha 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6484
EnsembleID ENSG00000112769
Uniprot Q16363

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LAMA4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LAMA4 GO:0005102,GO:0005201,GO:0005201,GO:0005576,GO:0005604,GO:0007155,GO:0030155,GO:0030334,GO:0045995,GO:0062023,GO:0062023,GO:0070062,GO:0120163

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LAMA4 hsa:3910 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa04510 Focal adhesion - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa05143 African trypanosomiasis - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa05146 Amoebiasis - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa05200 Pathways in cancer - Homo sapiens (human)
LAMA4 hsa:3910 path:hsa05222 Small cell lung cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LAMA4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LAMA4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 LAMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN LAMA4 N/A trascriptional regulation,stimulation inferred by curator TFlink
USF1 LAMA4 N/A trascriptional regulation,stimulation inferred by curator TFlink
USF2 LAMA4 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 LAMA4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000160683 LAMA4 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LAMA4 LAMC1 25361965 interaction type N/A PTMCode2
LAMC1 LAMA4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LGALS3 LAMA4 25348397 N/A physical interaction ComPPI
UNC119 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
GAPDH LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
APC LAMA4 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PILRA LAMA4 25348397 N/A physical interaction ComPPI
EEF1A1 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SUMO2 LAMA4 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ZHX1 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RTN4 LAMA4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COPS6 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LGALS8 LAMA4 25348397 N/A physical interaction ComPPI
FHL1 LAMA4 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
BRD7 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LRIF1 LAMA4 25348397 N/A two hybrid,physical interaction ComPPI
BCAM LAMA4 25348397 N/A physical interaction ComPPI
RIF1 LAMA4 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MED31 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
UBR1 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PTN LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LAMA4 TP53 16169070 24234451 25241761 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
LAMA4 TUBB2A 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LAMA4 EEF1A1P5 25348397 N/A physical interaction ComPPI
LAMA4 LGALS9 25348397 N/A physical interaction ComPPI
LAMA4 MCAM 25348397 N/A physical interaction ComPPI
LAMA4 CLEC14A 25348397 N/A physical interaction ComPPI
LAMA4 ATF7IP 15231748 24234451 25348397 physical association two hybrid ComPPI,IntAct
TNIP1 LAMA4 24234451 30561431 association virotrap IntAct
TNIP2 LAMA4 24234451 30561431 association virotrap IntAct

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