Gene Information gene info

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GENE：LPIN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LPIN1
FullNmae lipin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13345
EnsembleID ENSG00000134324
Uniprot Q14693

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LPIN1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LPIN1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LPIN1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LPIN1 GO:0003713,GO:0005515,GO:0005634,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005741,GO:0005783,GO:0005789,GO:0005829,GO:0006642,GO:0006654,GO:0007077,GO:0008195,GO:0008195,GO:0008195,GO:0009062,GO:0009062,GO:0019432,GO:0019432,GO:0019432,GO:0031100,GO:0031642,GO:0031965,GO:0032869,GO:0045740,GO:0045944,GO:0120162

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LPIN1 hsa:23175 path:hsa00561 Glycerolipid metabolism - Homo sapiens (human)
LPIN1 hsa:23175 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
LPIN1 hsa:23175 path:hsa01100 Metabolic pathways - Homo sapiens (human)
LPIN1 hsa:23175 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
LPIN1 hsa:23175 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LPIN1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LPIN1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 LPIN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 LPIN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C LPIN1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 LPIN1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFYA LPIN1 19553673 trascriptional regulation,stimulation inferred by curator TFlink
NFYB LPIN1 19553673 trascriptional regulation,stimulation inferred by curator TFlink
NFYC LPIN1 19553673 trascriptional regulation,stimulation inferred by curator TFlink
SREBF1 LPIN1 19553673 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LPIN1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00002075FA LPIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B341F LPIN1 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS0000330617 LPIN1 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS000006372A LPIN1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 LPIN1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC LPIN1 25416803 28287811 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000009C45F LPIN1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000002569A LPIN1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075B538 LPIN1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK6 LPIN1 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
PPARA LPIN1 25348397 N/A physical interaction ComPPI
NTRK1 LPIN1 25348397 N/A physical interaction ComPPI
BTRC LPIN1 25348397 N/A physical interaction ComPPI
CSNK1E LPIN1 25348397 N/A physical interaction ComPPI
PPP1CA LPIN1 24234451 25348397 25593058 association anti bait coimmunoprecipitation ComPPI,IntAct
XPO1 LPIN1 25348397 N/A physical interaction ComPPI
GEMIN5 LPIN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL1 LPIN1 25348397 N/A physical interaction ComPPI
NFATC4 LPIN1 25348397 N/A physical interaction ComPPI
TRIM25 LPIN1 25348397 N/A physical interaction ComPPI
FBXW11 LPIN1 25348397 N/A physical interaction ComPPI
HSP90B1 LPIN1 24234451 30021884 physical association cross-linking study IntAct
CTDNEP1 LPIN1 17420445 27898060 stimulant N/A OmniPath

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