GENE：MAFK
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MAFK |
| FullNmae | MAF bZIP transcription factor K |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6782 |
| EnsembleID | ENSG00000198517 |
| Uniprot | O60675 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MAFK | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MAFK | GO:0000122,GO:0000122,GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006357,GO:0043565,GO:0090575 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA1 | MAFK | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | MAFK | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | MAFK | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MAFK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00001A7F58 | MAFK | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000171CD1 | MAFK | 20371350 21572407 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | MAFK | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | MAFK | 20371350 21572407 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | MAFK | 20371350 21572407 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | MAFK | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | MAFK | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D2680 | MAFK | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | MAFK | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B7450 | MAFK | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | MAFK | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CC20C | MAFK | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000009A9A2 | MAFK | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | MAFK | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | MAFK | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000018D2BE | MAFK | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000038446A | MAFK | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000024DFCE | MAFK | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FF9C | MAFK | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000166778 | MAFK | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075E2C3 | MAFK | 23824327 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00000011DF | MAFK | 23824327 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000224AEA | MAFK | 19536157 23824327 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E780 | MAFK | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020579D | MAFK | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000239117 | MAFK | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0874 | MAFK | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | MAFK | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | MAFK | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005A8A8D | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000033B91D | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DABC0 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000FC8EB | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000272A92 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002373FD | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C83DA | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A939F | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000007A060 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004A6E26 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000018E6CD | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000032D69B | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C403E | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001ADE63 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077DDE | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000035D2F9 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000149319 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000017EA6A | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CCD18 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076E54 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004929F1 | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D15B | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EC1BE | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AD2AA | MAFK | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BACH1 | MAFK | 25361965 | interaction type | N/A | PTMCode2 |
| MAFK | BACH1 | 25361965 | interaction type | N/A | PTMCode2 |
| MAFK | NFE2L2 | 25361965 | interaction type | N/A | PTMCode2 |
| NFE2L2 | MAFK | 25361965 | interaction type | N/A | PTMCode2 |
| NFE2 | MAFK | 25361965 | interaction type | N/A | PTMCode2 |
| MAFK | NFE2 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CREBBP | MAFK | 25348397 | N/A | physical interaction | ComPPI |
| SMAD3 | MAFK | 25348397 | N/A | physical interaction | ComPPI |
| HIF1A | MAFK | 18538669 24234451 25348397 | N/A | surface plasmon resonance,physical interaction | ComPPI,IntAct |
| HDAC3 | MAFK | 25348397 | N/A | physical interaction | ComPPI |
| NFE2L2 | MAFK | 10747902 11013233 14525934 21988832 24234451 25348397 9150357 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach | ComPPI,HPRD,IntAct |
| PARP1 | MAFK | 25348397 | N/A | physical interaction | ComPPI |
| NFATC2 | MAFK | 25348397 | N/A | physical interaction | ComPPI |
| RELA | MAFK | 25348397 | N/A | physical interaction | ComPPI |
| HDAC2 | MAFK | 25348397 | N/A | physical interaction | ComPPI |
| NFE2 | MAFK | 14525934 25348397 27898060 8355703 9150357 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| MAFK | BACH1 | 14525934 24234451 25348397 26496610 8887638 | association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,IntAct |
| MAFK | MARS1 | 14525934 25348397 9878398 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| MAFK | NFE2L3 | 10037736 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
| MAFK | BACH2 | 14525934 17046816 24234451 25348397 27898060 8887638 | physical association | two hybrid,experimental interaction detection,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| MAFK | NFE2L1 | 12805554 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| MAFK | HOXD12 | 25348397 | N/A | physical interaction | ComPPI |
| MAFK | KAT6A | 17083329 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| MAFK | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| MAFK | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
| MAFK | DNMT3L | 25348397 | N/A | physical interaction | ComPPI |
| MAFK | MAFK | 14525934 8887638 | N/A | experimental interaction detection | HPRD |
| HDAC3 | MAFK | 18241676 27898060 | inhibition | N/A | OmniPath |
| HDAC1 | MAFK | 18241676 27898060 | inhibition | N/A | OmniPath |