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GENE：MAT2B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAT2B
FullNmae methionine adenosyltransferase 2 non-catalytic beta subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6905
EnsembleID ENSG00000038274
Uniprot Q9NZL9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAT2B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MAT2B GO:0005515,GO:0005634,GO:0005634,GO:0005829,GO:0006556,GO:0006556,GO:0006556,GO:0006730,GO:0019899,GO:0048269,GO:0048269,GO:0048269,GO:0048270,GO:0048270,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MAT2B hsa:27430 path:hsa00270 Cysteine and methionine metabolism - Homo sapiens (human)
MAT2B hsa:27430 path:hsa01100 Metabolic pathways - Homo sapiens (human)
MAT2B hsa:27430 path:hsa01230 Biosynthesis of amino acids - Homo sapiens (human)
MAT2B hsa:27430 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MAT2B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MAT2B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MAT2B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 MAT2B 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MAT2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MAT2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MAT2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MAT2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MAT2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MAT2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MAT2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 MAT2B 11337507 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 MAT2B 11337507 trascriptional regulation,stimulation inferred by curator TFlink
SP3 MAT2B N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 MAT2B 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 MAT2B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 MAT2B 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 MAT2B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000009262D MAT2B 24098708 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000007F792 MAT2B 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KPNA3 MAT2B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KPNA4 MAT2B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BAG3 MAT2B 25348397 N/A physical interaction ComPPI
TUBB MAT2B 25348397 N/A physical interaction ComPPI
MCM2 MAT2B 25348397 N/A physical interaction ComPPI
EIF5 MAT2B 25348397 N/A physical interaction ComPPI
GAPDH MAT2B 25348397 N/A physical interaction ComPPI
PDIA6 MAT2B 25348397 N/A physical interaction ComPPI
SNX1 MAT2B 25348397 N/A physical interaction ComPPI
PPP1CA MAT2B 25348397 N/A physical interaction ComPPI
XPO5 MAT2B 25348397 N/A physical interaction ComPPI
RABEP1 MAT2B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XPO1 MAT2B 25348397 N/A physical interaction ComPPI
YWHAQ MAT2B 25348397 N/A physical interaction ComPPI
TUBA1A MAT2B 25348397 N/A physical interaction ComPPI
DFFA MAT2B 25348397 N/A physical interaction ComPPI
STK24 MAT2B 25348397 N/A physical interaction ComPPI
ELAVL1 MAT2B 25348397 N/A physical interaction ComPPI
TRIM27 MAT2B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAT2B APP 25348397 N/A physical interaction ComPPI
MAT2B TNS3 25348397 N/A physical interaction ComPPI
MAT2B FBXO25 25348397 N/A physical interaction ComPPI
MAT2B EIF4H 25348397 N/A physical interaction ComPPI
MAT2B ATG7 25348397 N/A physical interaction ComPPI
MAT2B CNN2 25348397 N/A physical interaction ComPPI
MAT2B FERMT2 25348397 N/A physical interaction ComPPI
MAT2B G6PD 25348397 N/A physical interaction ComPPI
MAT2B PPP3CA 25348397 N/A physical interaction ComPPI
MAT2B NASP 25348397 N/A physical interaction ComPPI
MAT2B UGDH 25348397 N/A physical interaction ComPPI
MAT2B PLA2G6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CAPNS1 MAT2B 25348397 N/A physical interaction ComPPI
HRH1 MAT2B 24234451 28298427 physical association ubiquitin reconstruction IntAct

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