GENE：MTTP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MTTP |
| FullNmae | microsomal triglyceride transfer protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:7467 |
| EnsembleID | ENSG00000138823 |
| Uniprot | P55157 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MTTP | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MTTP | GO:0005319,GO:0005515,GO:0005548,GO:0005783,GO:0005783,GO:0005788,GO:0005794,GO:0005794,GO:0005829,GO:0006629,GO:0006641,GO:0007623,GO:0008289,GO:0009306,GO:0009306,GO:0015914,GO:0015918,GO:0016323,GO:0031526,GO:0031528,GO:0031982,GO:0034185,GO:0034197,GO:0034197,GO:0034374,GO:0034377,GO:0034377,GO:0034378,GO:0034379,GO:0042157,GO:0042632,GO:0042953,GO:0043235,GO:0044877,GO:0046982,GO:0051592,GO:0051649,GO:0120009,GO:0120014,GO:0120019,GO:0120019,GO:0120020,GO:0120020,GO:0140344,GO:0140344,GO:1902388,GO:1902389,GO:1904121 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MTTP | hsa:4547 | path:hsa04975 | Fat digestion and absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SREBF2 | MTTP | 10455139 | trascriptional regulation,stimulation | inferred by curator,electrophoretic mobility shift assay | TFlink |
| HNF1A | MTTP | 15337761 18697801 22357705 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MTTP | 18971253 22357705 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | MTTP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NR2F1 | MTTP | 22357705 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NF2 | MTTP | 25348397 | N/A | physical interaction | ComPPI |
| P4HB | MTTP | 25348397 | N/A | physical interaction | ComPPI |
| MTTP | HSP90B1 | 14525934 25348397 9694898 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| MTTP | APOB | 11358959 14525934 25348397 9915855 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| MTTP | PDIA2 | 25348397 | N/A | physical interaction | ComPPI |
| SNW1 | MTTP | 24234451 30021884 | physical association | cross-linking study | IntAct |
| MTTP | APOB | 11358959 23721961 26224785 27898060 9915855 | stimulant | N/A | OmniPath |