Gene Information gene info

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GENE：P4HA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol P4HA1
FullNmae prolyl 4-hydroxylase subunit alpha 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8546
EnsembleID ENSG00000122884
Uniprot P13674

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
P4HA1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
P4HA1 GO:0004656,GO:0004656,GO:0005506,GO:0005515,GO:0005739,GO:0005783,GO:0005783,GO:0005788,GO:0016020,GO:0016222,GO:0018401,GO:0030199,GO:0031418,GO:0042802,GO:0043231

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
P4HA1 hsa:5033 path:hsa00330 Arginine and proline metabolism - Homo sapiens (human)
P4HA1 hsa:5033 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF7 P4HA1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR P4HA1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 P4HA1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A P4HA1 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
USF1 P4HA1 16488890 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
USF2 P4HA1 16488890 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 P4HA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 P4HA1 21829524 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 P4HA1 21829524 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC P4HA1 23178710 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00003380CC P4HA1 23178710 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000237AF9 P4HA1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D P4HA1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD P4HA1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004F4657 P4HA1 22942087 25416803 mrna cleavage,inhibition array technology TarBase
URS00001DE669 P4HA1 25416803 26966067 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CTDSP2 P4HA1 25348397 N/A physical interaction ComPPI
TOMM22 P4HA1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
UBL4A P4HA1 25348397 N/A physical interaction ComPPI
SMN1 P4HA1 25348397 N/A physical interaction ComPPI
PEF1 P4HA1 25348397 N/A physical interaction ComPPI
FIP1L1 P4HA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM8A P4HA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FOXG1 P4HA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GLI1 P4HA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CUL3 P4HA1 25348397 N/A physical interaction ComPPI
IRS4 P4HA1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
P4HB P4HA1 25348397 N/A physical interaction ComPPI
MYC P4HA1 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CFTR P4HA1 25348397 N/A physical interaction ComPPI
PARD6B P4HA1 25348397 N/A physical interaction ComPPI
COLQ P4HA1 25348397 N/A physical interaction ComPPI
EVPL P4HA1 25348397 N/A physical interaction ComPPI
HTT P4HA1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
WWOX P4HA1 25348397 N/A physical interaction ComPPI
CDK9 P4HA1 25348397 N/A physical interaction ComPPI
PDCD6 P4HA1 25348397 N/A physical interaction ComPPI
RNF41 P4HA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 P4HA1 25348397 N/A physical interaction ComPPI
HDAC10 P4HA1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGOLN2 P4HA1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IRF7 P4HA1 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPEF1 P4HA1 24234451 25348397 28330616 association pull down ComPPI,IntAct
FOXL2 P4HA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AURKAIP1 P4HA1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TSC22D4 P4HA1 25348397 N/A physical interaction ComPPI
PSMD5 P4HA1 25348397 N/A physical interaction ComPPI
CPSF3 P4HA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
L3MBTL1 P4HA1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
FOXP3 P4HA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
UBA5 P4HA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FOXS1 P4HA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
COX4I1 P4HA1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 P4HA1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FOXA3 P4HA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MLF2 P4HA1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
AATK P4HA1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK4 P4HA1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
L3MBTL3 P4HA1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
P4HA1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
P4HA1 TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
P4HA1 SLAIN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
P4HA1 ZNF526 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
P4HA1 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB P4HA1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
P4HA1 P4HA1 24207127 24234451 N/A molecular sieving,static light scattering,x-ray crystallography,x ray scattering IntAct
P4HA1 PRPF40B 24234451 30021884 physical association cross-linking study IntAct
P4HA1 GTF2E1 24234451 30021884 physical association cross-linking study IntAct
P4HA2 P4HA1 24234451 30021884 physical association cross-linking study IntAct
IRF7 P4HA1 21903422 27898060 N/A N/A OmniPath

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