Gene Information gene info

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GENE：PAX5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PAX5
FullNmae paired box 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8619
EnsembleID ENSG00000196092
Uniprot Q02548

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PAX5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PAX5 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0005515,GO:0005654,GO:0005654,GO:0006357,GO:0006366,GO:0007283,GO:0021670,GO:0021987,GO:0030183,GO:0030534,GO:0035914,GO:0045944,GO:0048701,GO:0048856

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PAX5 hsa:5079 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PAX5 AR 17011549 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PAX5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 PAX5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PAX5 18971253 21319196 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PAX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 PAX5 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT5A PAX5 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT5B PAX5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000023F008 PAX5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C PAX5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA PAX5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 PAX5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 PAX5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA PAX5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B PAX5 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 PAX5 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 PAX5 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B PAX5 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 PAX5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 PAX5 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KPNA2 PAX5 25361965 interaction type N/A PTMCode2
PAX5 KPNA2 25361965 interaction type N/A PTMCode2
MYB PAX5 25361965 interaction type N/A PTMCode2
PAX5 MYB 25361965 interaction type N/A PTMCode2
ID2 PAX5 25361965 interaction type N/A PTMCode2
PAX5 ID2 25361965 interaction type N/A PTMCode2
RUNX1 PAX5 25361965 interaction type N/A PTMCode2
PAX5 RUNX1 25361965 interaction type N/A PTMCode2
PAX5 TLE4 25361965 interaction type N/A PTMCode2
TLE4 PAX5 25361965 interaction type N/A PTMCode2
EBF1 PAX5 25361965 interaction type N/A PTMCode2
PAX5 EBF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KLHL38 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCAS2 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DAXX PAX5 11799127 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPK9 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CKS1B PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBXN2B PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-8 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PNMA5 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMN1 PAX5 25348397 N/A two hybrid ComPPI
STAC PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LDLRAP1 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK1 PAX5 25348397 N/A physical interaction ComPPI
TBP PAX5 10197586 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RB1 PAX5 10197586 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EP300 PAX5 21357426 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HGS PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSNK2A1 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SAE1 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ID3 PAX5 12054881 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TLK2 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DTX2 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NEIL2 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GNG13 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GRHL2 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDK3 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNC PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KMT2A PAX5 24234451 24735925 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RUNX1 PAX5 10455134 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NGLY1 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXC8 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 TLE4 10811620 12153506 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PAX5 MYB 11781241 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PAX5 CXORF38 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 C1ORF109 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 CIB3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 SEC14L4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 KRTAP9-3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 ACOT12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 LONRF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 UBXN7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 RAD52 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMGB3 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAX5 PAX5 10022910 14525934 N/A experimental interaction detection HPRD
KPNA2 PAX5 10748034 14525934 N/A experimental interaction detection,two hybrid HPRD
KPNA1 PAX5 10748034 14525934 N/A experimental interaction detection,two hybrid HPRD
EBF1 PAX5 14525934 14594818 27898060 N/A experimental interaction detection HPRD,OmniPath
PAX5 ID2 11134340 14525934 N/A experimental interaction detection HPRD
PAX5 CREBBP 11799127 14525934 N/A experimental interaction detection,two hybrid HPRD
PAX5 ETS1 10022910 12221090 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
PAX5 PDCD1 15676205 27898060 inhibition N/A OmniPath
PAX5 CD79A 15676205 27898060 stimulant N/A OmniPath
PAX5 CSF1R 15676205 27898060 inhibition N/A OmniPath
PAX5 CD19 15676205 27898060 stimulant N/A OmniPath
PAX5 BLK 10455134 27898060 stimulant N/A OmniPath

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