GENE：PDPN
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PDPN |
| FullNmae | podoplanin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29602 |
| EnsembleID | ENSG00000162493 |
| Uniprot | Q86YL7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PDPN | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PDPN | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PDPN | GO:0001726,GO:0001946,GO:0005102,GO:0005102,GO:0005515,GO:0005739,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0007266,GO:0007266,GO:0008285,GO:0008360,GO:0010718,GO:0010718,GO:0016020,GO:0016323,GO:0016323,GO:0016324,GO:0016324,GO:0016477,GO:0019956,GO:0019956,GO:0030027,GO:0030027,GO:0030054,GO:0030168,GO:0030175,GO:0030175,GO:0030324,GO:0030324,GO:0030335,GO:0030335,GO:0031258,GO:0031410,GO:0031527,GO:0031528,GO:0032587,GO:0042995,GO:0043066,GO:0044319,GO:0045121,GO:0048535,GO:0051087,GO:0051087,GO:0055093,GO:0060838,GO:0061851,GO:0070161,GO:0070252,GO:0070252,GO:0090091,GO:0090091,GO:0097197,GO:0098609,GO:1900024,GO:1900024,GO:1901731,GO:1901731,GO:1901731,GO:1904328,GO:1904328,GO:2000392,GO:2000392 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PDPN | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | PDPN | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CTCF | PDPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PDPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PDPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PDPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | PDPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | PDPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000B989F | PDPN | 23246488 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
| URS00000B989F | PDPN | 23246488 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS0000355E82 | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000002569A | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009C45F | PDPN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006B702 | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000527B00 | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043C1C3 | PDPN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | PDPN | 23706177 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC4BD | PDPN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TOM1L1 | PDPN | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CLEC1B | PDPN | 25348397 25458834 27898060 | N/A | nuclear magnetic resonance,x-ray crystallography,physical interaction | ComPPI,OmniPath |
| PDPN | TMEM14B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RBCK1 | PDPN | 24234451 30561431 | association | virotrap | IntAct |
| SHARPIN | PDPN | 24234451 30561431 | association | virotrap | IntAct |
| TRADD | PDPN | 24234451 30561431 | association | virotrap | IntAct |