GENE:PLXNA1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PLXNA1 |
| FullNmae | plexin A1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9099 |
| EnsembleID | ENSG00000114554 |
| Uniprot | Q9UIW2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PLXNA1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PLXNA1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PLXNA1 | GO:0002116,GO:0002116,GO:0005654,GO:0005829,GO:0005886,GO:0007162,GO:0008360,GO:0014910,GO:0017154,GO:0017154,GO:0021628,GO:0021828,GO:0030334,GO:0043087,GO:0050772,GO:0060666,GO:0070062,GO:1902287,GO:1990138 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PLXNA1 | hsa:5361 | path:hsa04360 | Axon guidance - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | PLXNA1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | PLXNA1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | PLXNA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| AR | PLXNA1 | 23318417 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CIITA | PLXNA1 | 15814328 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NR5A1 | PLXNA1 | 17566092 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PAWR | PLXNA1 | 11502835 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| WT1 | PLXNA1 | 11502835 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | PLXNA1 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001EFBE3 | PLXNA1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003D5391 | PLXNA1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005651EE | PLXNA1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000021D7C8 | PLXNA1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000042E1F | PLXNA1 | 22473208 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00002075FA | PLXNA1 | 22473208 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS0000065D58 | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CF5F | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DE669 | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | PLXNA1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023F008 | PLXNA1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000009A9A2 | PLXNA1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEF5F | PLXNA1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | PLXNA1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000060AABB | PLXNA1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004C5774 | PLXNA1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | PLXNA1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F1B8C | PLXNA1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | PLXNA1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000266339 | PLXNA1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| KDR | PLXNA1 | 25348397 | N/A | physical interaction | ComPPI |
| PDIA3 | PLXNA1 | 17170699 24234451 25348397 | disulfide bond | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FES | PLXNA1 | 12093729 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| PLXNA1 | PLXNB1 | 12559962 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD |
| PLXNA1 | RHOD | 11784792 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| PLXNA1 | RND1 | 11108845 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| PLXNA1 | AKT1 | 14525934 15187088 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| PLXNA1 | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | HLA-DRA | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | TAZ | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | LGALS9 | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | PTCH1 | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | PTPRK | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | GAN | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | OS9 | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | DEFA5 | 25348397 | N/A | physical interaction | ComPPI |
| PLXNA1 | DEFA1 | 25348397 | N/A | physical interaction | ComPPI |
| L1CAM | PLXNA1 | 10520994 15121181 27898060 | stimulant | N/A | OmniPath |
