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GENE：PTK7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTK7
FullNmae protein tyrosine kinase 7 (inactive)
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9618
EnsembleID ENSG00000112655
Uniprot Q13308

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTK7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTK7 GO:0001736,GO:0001822,GO:0003281,GO:0003401,GO:0004672,GO:0005515,GO:0005524,GO:0005886,GO:0005911,GO:0005911,GO:0005925,GO:0007156,GO:0007165,GO:0007411,GO:0008046,GO:0010976,GO:0016477,GO:0030036,GO:0030424,GO:0042060,GO:0043025,GO:0045198,GO:0050808,GO:0060026,GO:0060484,GO:0060828,GO:0060976,GO:0071300,GO:0090103,GO:0090179,GO:0090263

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PTK7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PTK7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PTK7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PTK7 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C PTK7 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PTK7 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PTK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 PTK7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PTK7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB PTK7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F72ED PTK7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003CC709 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000279B6F PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000519450 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000458AD2 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000057FDB8 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00006097A6 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000015A0D9 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001919B0 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049FAE8 PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C PTK7 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CTDSP2 PTK7 25348397 N/A physical interaction ComPPI
KRTAP10-8 PTK7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN6 PTK7 25348397 N/A physical interaction ComPPI
MDFI PTK7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN11 PTK7 25348397 N/A physical interaction ComPPI
PTPRO PTK7 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPM1A PTK7 25348397 N/A physical interaction ComPPI
NTRK1 PTK7 25348397 N/A physical interaction ComPPI
PTPN7 PTK7 25348397 N/A physical interaction ComPPI
HNRNPL PTK7 25348397 N/A physical interaction ComPPI
PTPN12 PTK7 25348397 N/A physical interaction ComPPI
DUSP14 PTK7 25348397 N/A physical interaction ComPPI
CTNNB1 PTK7 21132015 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct
PTEN PTK7 25348397 N/A physical interaction ComPPI
CDC14A PTK7 25348397 N/A physical interaction ComPPI
TSHR PTK7 25348397 N/A physical interaction ComPPI
PPM1B PTK7 25348397 N/A physical interaction ComPPI
DUSP10 PTK7 25348397 N/A physical interaction ComPPI
CLNK PTK7 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
PPP3CA PTK7 25348397 N/A physical interaction ComPPI
PPP3CB PTK7 25348397 N/A physical interaction ComPPI
ILKAP PTK7 25348397 N/A physical interaction ComPPI
DUSP19 PTK7 25348397 N/A physical interaction ComPPI
PPM1F PTK7 25348397 N/A physical interaction ComPPI
PTK7 RYK 25348397 N/A physical interaction ComPPI
PTK7 PPM1G 25348397 N/A physical interaction ComPPI
PTK7 PPM1K 25348397 N/A physical interaction ComPPI
PTK7 DUSP15 25348397 N/A physical interaction ComPPI
PTK7 DUSP26 25348397 N/A physical interaction ComPPI
NCL PTK7 24234451 30021884 physical association cross-linking study IntAct
PTK7 CTNNB1 21132015 23151663 27898060 inhibition N/A OmniPath
RACK1 PTK7 21350015 27898060 stimulant N/A OmniPath

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