Gene Information gene info

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GENE：SERPINB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SERPINB2
FullNmae serpin family B member 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8584
EnsembleID ENSG00000197632
Uniprot P05120

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SERPINB2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SERPINB2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SERPINB2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SERPINB2 GO:0001533,GO:0004867,GO:0004867,GO:0005576,GO:0005615,GO:0005737,GO:0005886,GO:0010951,GO:0042730,GO:0043066

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SERPINB2 hsa:5055 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 SERPINB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SERPINB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SERPINB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SERPINB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SERPINB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SERPINB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZFP36 SERPINB2 12578825 trascriptional regulation,stimulation inferred by curator TFlink
ZNF823 SERPINB2 12578825 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 SERPINB2 N/A trascriptional regulation,stimulation inferred by curator TFlink
JUN SERPINB2 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 SERPINB2 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A SERPINB2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 SERPINB2 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
YES1 SERPINB2 25348397 N/A physical interaction ComPPI
PPFIA1 SERPINB2 25348397 N/A physical interaction ComPPI
VAV1 SERPINB2 25348397 N/A physical interaction ComPPI
RB1 SERPINB2 12944478 14525934 16397580 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PPP1R12A SERPINB2 25348397 N/A physical interaction ComPPI
OSBP SERPINB2 25348397 N/A physical interaction ComPPI
SERPINB2 IRF3 12883638 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SERPINB2 PRPF8 14525934 15346200 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
SERPINB2 PLAU 14525934 2161846 2166055 25348397 27898060 8388810 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
SERPINB2 RBL2 25348397 N/A physical interaction ComPPI
SERPINB2 APP 25348397 N/A physical interaction ComPPI
SERPINB2 KIR3DS1 25348397 N/A physical interaction ComPPI
SERPINB2 RAPGEF6 25348397 N/A physical interaction ComPPI
SERPINB2 HDLBP 25348397 N/A physical interaction ComPPI
SERPINB2 PTK2 25348397 N/A physical interaction ComPPI
SERPINB2 TAB1 25348397 N/A physical interaction ComPPI
SERPINB2 EEA1 25348397 N/A physical interaction ComPPI
SERPINB2 ARHGAP35 25348397 N/A physical interaction ComPPI
SERPINB2 LPP 25348397 N/A physical interaction ComPPI
SERPINB2 ASPSCR1 25348397 N/A physical interaction ComPPI
SERPINB2 GDF5 25348397 N/A physical interaction ComPPI
SERPINB2 KLC2 25348397 N/A physical interaction ComPPI
SERPINB2 TBL1X 25348397 N/A physical interaction ComPPI
SERPINB2 DDX42 25348397 N/A physical interaction ComPPI
SERPINB2 TAF5L 25348397 N/A physical interaction ComPPI
SERPINB2 TAF5 25348397 N/A physical interaction ComPPI
SERPINB2 NUP214 25348397 N/A physical interaction ComPPI
SERPINB2 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP2K2 SERPINB2 25348397 N/A physical interaction ComPPI
PSMB1 SERPINB2 14525934 14732874 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
DDX19B SERPINB2 25348397 N/A physical interaction ComPPI
GSK3A SERPINB2 27898060 6090457 6091765 stimulant N/A OmniPath
SERPINB2 PPP1CC 11320080 11812771 27898060 6327437 inhibition N/A OmniPath
CSNK1G1 SERPINB2 27898060 6090457 stimulant N/A OmniPath

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