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GENE：SIN3B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SIN3B
FullNmae SIN3 transcription regulator family member B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19354
EnsembleID ENSG00000127511
Uniprot O75182

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SIN3B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SIN3B GO:0000122,GO:0000122,GO:0000785,GO:0000805,GO:0000806,GO:0001741,GO:0003682,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0016580,GO:0016580,GO:0030336,GO:0030849

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F6 SIN3B 15536069 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SIN3B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SIN3B 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SIN3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SIN3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SIN3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SIN3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SIN3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SIN3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SIN3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SIN3B 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 SIN3B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016FF9C SIN3B 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001D4A78 SIN3B 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CC379 SIN3B 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000345DEB SIN3B 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000116F83 SIN3B 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E226A SIN3B 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GOLGA2 SIN3B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TFAP4 SIN3B 25348397 N/A physical interaction ComPPI
MORF4L2 SIN3B 25348397 N/A physical interaction ComPPI
SMARCE1 SIN3B 25348397 N/A physical interaction ComPPI
PPP1CC SIN3B 25348397 N/A two hybrid ComPPI
MRGBP SIN3B 25348397 N/A physical interaction ComPPI
BRMS1 SIN3B 25348397 N/A physical interaction ComPPI
SMN1 SIN3B 25348397 N/A physical interaction ComPPI
SETDB1 SIN3B 12398767 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HCFC1 SIN3B 12670868 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AR SIN3B 25348397 N/A physical interaction ComPPI
ACTN4 SIN3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCA4 SIN3B 25348397 N/A physical interaction ComPPI
SIN3A SIN3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC SIN3B 24234451 24951594 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,chromatin immunoprecipitation assay,confocal microscopy,proximity ligation assay ComPPI,IntAct
CBFA2T3 SIN3B 25348397 N/A physical interaction ComPPI
AKAP12 SIN3B 25348397 N/A physical interaction ComPPI
SMARCB1 SIN3B 25348397 N/A physical interaction ComPPI
RBBP4 SIN3B 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
KDM5A SIN3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MORF4L1 SIN3B 25348397 N/A physical interaction ComPPI
COPS2 SIN3B 25348397 N/A physical interaction ComPPI
ZBTB16 SIN3B 14525934 25348397 9627120 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SOX2 SIN3B 25348397 N/A physical interaction ComPPI
H3-4 SIN3B 25348397 N/A physical interaction ComPPI
HDAC2 SIN3B 16464847 21258344 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MXD1 SIN3B 14525934 24234451 24951594 25348397 7889570 physical association experimental interaction detection,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
CIITA SIN3B 25348397 N/A physical interaction ComPPI
IKZF3 SIN3B 25348397 N/A physical interaction ComPPI
AURKA SIN3B 25348397 N/A physical interaction ComPPI
MDC1 SIN3B 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
STX3 SIN3B 25348397 N/A physical interaction ComPPI
RFX5 SIN3B 16464847 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SAP30 SIN3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MXI1 SIN3B 14525934 15467743 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SIN3B MAD1L1 11101889 11370785 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SIN3B IKZF1 10357820 12015313 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SIN3B IKZF4 12015313 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SIN3B HDAC9 12590135 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SIN3B REST 10570134 25348397 27898060 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
SIN3B HDAC1 11959842 14525934 23752268 24234451 24951594 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
SIN3B IKZF2 25348397 N/A physical interaction ComPPI
SIN3B SUDS3 25348397 N/A physical interaction ComPPI
SIN3B NSD2 25348397 N/A physical interaction ComPPI
SIN3B RNF220 20170641 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SIN3B SAP25 25348397 N/A physical interaction ComPPI
SIN3B SMARCA2 25348397 N/A physical interaction ComPPI
SIN3B MYT1 25348397 N/A physical interaction ComPPI
SIN3B ZBTB4 25348397 N/A physical interaction ComPPI
SIN3B ARID4A 25348397 N/A physical interaction ComPPI
SIN3B PBX1 25348397 N/A physical interaction ComPPI
SIN3B NR1D2 25348397 N/A physical interaction ComPPI
SIN3B KLF16 25348397 N/A physical interaction ComPPI
SIN3B TP53 22028823 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SIN3B ESR1 25348397 N/A physical interaction ComPPI
SIN3B GATAD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIN3B RBBP7 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SIN3B MYO5C 25348397 N/A physical interaction ComPPI
SIN3B PHF12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIN3B PNPLA8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIN3B EMSY 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIN3B SAP130 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIN3B TNRC18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIN3B FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SIN3B USP37 25348397 N/A physical interaction ComPPI
SIN3B ZNF131 25348397 N/A physical interaction ComPPI
SIN3B ING2 25348397 N/A physical interaction ComPPI
SIN3B SINHCAF 25348397 N/A physical interaction ComPPI
SIN3B PHF23 25348397 N/A physical interaction ComPPI
LSM4 SIN3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK4 SIN3B 24234451 24951594 association chromatin immunoprecipitation assay IntAct
SIN3B SRD5A1 24234451 24951594 association chromatin immunoprecipitation assay IntAct
SIN3B NCL 24234451 24951594 association chromatin immunoprecipitation assay IntAct

Visualization










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