GENE：ST6GAL1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ST6GAL1 |
| FullNmae | ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10860 |
| EnsembleID | ENSG00000073849 |
| Uniprot | P15907 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ST6GAL1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ST6GAL1 | GO:0000138,GO:0000139,GO:0000139,GO:0003835,GO:0003835,GO:0003835,GO:0005515,GO:0005576,GO:0005794,GO:0005797,GO:0006054,GO:0006959,GO:0008373,GO:0008373,GO:0016266,GO:0018279,GO:0018279,GO:0019082,GO:0032580,GO:0032946,GO:0042803,GO:0045471,GO:0050922,GO:0097503,GO:0097503,GO:1900024,GO:2000110 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ST6GAL1 | hsa:6480 | path:hsa00510 | N-Glycan biosynthesis - Homo sapiens (human) |
| ST6GAL1 | hsa:6480 | path:hsa00514 | Other types of O-glycan biosynthesis - Homo sapiens (human) |
| ST6GAL1 | hsa:6480 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ST6GAL1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ST6GAL1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ST6GAL1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | ST6GAL1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | ST6GAL1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | ST6GAL1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | ST6GAL1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | ST6GAL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| POU2F1 | ST6GAL1 | 10814704 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | ST6GAL1 | 10814704 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | ST6GAL1 | 10814704 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F2 | ST6GAL1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | ST6GAL1 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009262D | ST6GAL1 | 18591254 22473208 25416803 | mrna cleavage,inhibition | array technology,clip | TarBase |
| URS000035CC3E | ST6GAL1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000040FA88 | ST6GAL1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000553F51 | ST6GAL1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000482389 | ST6GAL1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GLMN | ST6GAL1 | 25348397 | N/A | physical interaction | ComPPI |
| TNPO3 | ST6GAL1 | 25348397 | N/A | physical interaction | ComPPI |
| WAPL | ST6GAL1 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | CD22 | 14525934 25348397 8702538 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| ST6GAL1 | ARFGEF3 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | ATRIP | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | ZYG11B | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | HOOK2 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | SAAL1 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | USP28 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | PRMT9 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | INTS3 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | INTS12 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | PIP4K2A | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | ERGIC2 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | HLA-C | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | HEATR3 | 25348397 | N/A | physical interaction | ComPPI |
| ST6GAL1 | ST6GAL1 | 11356854 14525934 | N/A | experimental interaction detection | HPRD |