GENE：THY1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | THY1 |
| FullNmae | Thy-1 cell surface antigen |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11801 |
| EnsembleID | ENSG00000154096 |
| Uniprot | P04216 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| THY1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| THY1 | GO:0001525,GO:0001525,GO:0001952,GO:0002693,GO:0005096,GO:0005096,GO:0005178,GO:0005178,GO:0005178,GO:0005515,GO:0005576,GO:0005783,GO:0005886,GO:0005886,GO:0005925,GO:0006469,GO:0006469,GO:0007010,GO:0007010,GO:0007229,GO:0007267,GO:0009897,GO:0009986,GO:0016324,GO:0019901,GO:0030336,GO:0030336,GO:0030425,GO:0030426,GO:0030673,GO:0032590,GO:0032809,GO:0034113,GO:0034235,GO:0034235,GO:0043113,GO:0043547,GO:0043547,GO:0045121,GO:0045121,GO:0046549,GO:0046549,GO:0048041,GO:0048041,GO:0050771,GO:0050771,GO:0050852,GO:0050852,GO:0050860,GO:0050870,GO:0050870,GO:0051281,GO:0051281,GO:0051894,GO:0070062,GO:0070571,GO:0098609,GO:2000298 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| THY1 | hsa:7070 | path:hsa04670 | Leukocyte transendothelial migration - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | THY1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| EGR1 | THY1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | THY1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| POU5F1 | THY1 | 17068183 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000100748 | THY1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000023BE29 | THY1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000913AC | THY1 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C403E | THY1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | THY1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | THY1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | THY1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001270D3 | THY1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004C5774 | THY1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D15B | THY1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | THY1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| THY1 | LCK | 25361965 | interaction type | N/A | PTMCode2 |
| LCK | THY1 | 25361965 | interaction type | N/A | PTMCode2 |
| THY1 | FYN | 25361965 | interaction type | N/A | PTMCode2 |
| FYN | THY1 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGAV | THY1 | 25361965 | interaction type | N/A | PTMCode2 |
| THY1 | ITGAV | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | THY1 | 25361965 | interaction type | N/A | PTMCode2 |
| THY1 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SNRPC | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2I | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| UBL4A | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| LCK | THY1 | 1351058 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| FAP | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| CLK1 | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| HTT | THY1 | 17500595 24234451 25348397 | association | pull down | ComPPI,IntAct |
| CTTN | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| FYN | THY1 | 1351058 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| ATP6V1E1 | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| TIMM44 | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| TIAL1 | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| UBE4B | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| ATXN7 | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| SARNP | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| VDAC3 | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| THY1 | ATXN1L | 25348397 | N/A | physical interaction | ComPPI |
| THY1 | SUGP1 | 25348397 | N/A | physical interaction | ComPPI |
| THY1 | SCO2 | 25348397 | N/A | physical interaction | ComPPI |
| THY1 | ZFR | 25348397 | N/A | physical interaction | ComPPI |
| THY1 | NNT | 25348397 | N/A | physical interaction | ComPPI |
| THY1 | MPLKIP | 25348397 | N/A | physical interaction | ComPPI |
| THY1 | UBAP2 | 25348397 | N/A | physical interaction | ComPPI |
| MRPL53 | THY1 | 25348397 | N/A | physical interaction | ComPPI |
| ITGAM | THY1 | 14525934 15004192 | N/A | experimental interaction detection | HPRD |
| THY1 | THY1 | 1347022 14525934 | N/A | experimental interaction detection | HPRD |
| THY1 | ITGAV | 14525934 15897908 | N/A | experimental interaction detection | HPRD |
| THY1 | ITGB3 | 14525934 15897908 | N/A | experimental interaction detection | HPRD |
| CCR8 | THY1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
| HTR6 | THY1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
| L1TD1 | THY1 | 24234451 25702638 | association | anti bait coimmunoprecipitation | IntAct |
| STAT6 | THY1 | 17312100 27898060 | stimulant | N/A | OmniPath |