GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
UCHL3 |
| FullNmae |
ubiquitin C-terminal hydrolase L3 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:12515 |
| EnsembleID |
ENSG00000118939 |
| Uniprot |
P15374 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| UCHL3 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| UCHL3 |
GO:0004843,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006511,GO:0008233,GO:0016567,GO:0016579,GO:0016579,GO:0019784,GO:0030163,GO:0043130,GO:0043687 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
UCHL3 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| TP53 |
UCHL3 |
18922183
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| SMARCA4 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXP1 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| RUNX1 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00000ED600 |
UCHL3 |
20215506
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS0000345DEB |
UCHL3 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00004719AB |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002A79D1 |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000085F64 |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000076B539 |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000002569A |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00001A4ABF |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00005D986D |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000508C13 |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002E628F |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000075994C |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000366551 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000053B1E8 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000018CD09 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002C0FCB |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00004B4B85 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ATM |
UCHL3 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
| COPS6 |
UCHL3 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| UCHL3 |
COPS6 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| NEDD8 |
UCHL3 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| UCHL3 |
NEDD8 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| MAPRE1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| USP20 |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| PPIB |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ZNRD2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| BAG3 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| IMPDH2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| SNRPD1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| XIAP |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBL7 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| SMAD1 |
UCHL3 |
21453705
24234451
25348397
27898060
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct,OmniPath |
| ZYX |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| COPS5 |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| UBE2L3 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ARHGDIA |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBB |
UCHL3 |
15531586
24234451
25348397
|
N/A |
x-ray crystallography |
ComPPI,IntAct |
| UBC |
UCHL3 |
10518943
14673145
15531586
20622874
22284438
23801757
25348397
25590432
27898060
9521656
9790970
|
N/A |
physical interaction |
ComPPI,OmniPath |
| DLD |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PGD |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PLA2G2A |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ENO1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CDH1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| STIP1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| P4HB |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PEBP1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TAGLN |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RDX |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GDI1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBA6 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RAD51 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATM |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CLPB |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| SUMO3 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ZRANB2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NEDD8 |
UCHL3 |
14525934
25348397
9790970
|
N/A |
two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid |
ComPPI,HPRD |
| ACAA2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TPD52L1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TRIM63 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ZEB1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| YAP1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TTC1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBE2A |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| COPS6 |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| CSE1L |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MSN |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PJA1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBA1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PCMT1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBE4B |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBQLN1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TRIM27 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PBX1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBE2V1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TSN |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
ATXN7L3 |
14525934
16713569
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid |
ComPPI,HPRD,IntAct |
| UCHL3 |
NSG2 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| UCHL3 |
POGK |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| UCHL3 |
UBE2S |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
TRIM55 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
TRIM54 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
USP21 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
USP15 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
USP28 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
ZFYVE19 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
AHCYL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
USP48 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
USP9X |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
USP34 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
USP5 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
UBXN7 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
UBR1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
UNK |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
ATP6V1F |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
TTC9C |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
SULT1A1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
VPS33B |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
NT5DC1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
LONRF1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
ZMYM6 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
GPX4 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
HINT1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
ENO2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
EZR |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
HSD17B10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
ISYNA1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
NUP93 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
SMS |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
SOD2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
TAGLN2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
TPD52 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UCHL3 |
OTUB1 |
24234451
25348397
26752685
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| ZNF593 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization