GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
UCHL3 |
FullNmae |
ubiquitin C-terminal hydrolase L3 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:12515 |
EnsembleID |
ENSG00000118939 |
Uniprot |
P15374 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
UCHL3 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
UCHL3 |
GO:0004843,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006511,GO:0008233,GO:0016567,GO:0016579,GO:0016579,GO:0019784,GO:0030163,GO:0043130,GO:0043687 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
UCHL3 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
TP53 |
UCHL3 |
18922183
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
SMARCA4 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
RUNX1 |
UCHL3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00000ED600 |
UCHL3 |
20215506
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS0000345DEB |
UCHL3 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS00004719AB |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002A79D1 |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000085F64 |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000076B539 |
UCHL3 |
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000002569A |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001A4ABF |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005D986D |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000508C13 |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002E628F |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075994C |
UCHL3 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000366551 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000053B1E8 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000018CD09 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002C0FCB |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004B4B85 |
UCHL3 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ATM |
UCHL3 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
COPS6 |
UCHL3 |
25361965
|
interaction type |
N/A |
PTMCode2 |
UCHL3 |
COPS6 |
25361965
|
interaction type |
N/A |
PTMCode2 |
NEDD8 |
UCHL3 |
25361965
|
interaction type |
N/A |
PTMCode2 |
UCHL3 |
NEDD8 |
25361965
|
interaction type |
N/A |
PTMCode2 |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
MAPRE1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
USP20 |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
PPIB |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
ZNRD2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
BAG3 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
IMPDH2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
SNRPD1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
XIAP |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBL7 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
SMAD1 |
UCHL3 |
21453705
24234451
25348397
27898060
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct,OmniPath |
ZYX |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
COPS5 |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
UBE2L3 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
ARHGDIA |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBB |
UCHL3 |
15531586
24234451
25348397
|
N/A |
x-ray crystallography |
ComPPI,IntAct |
UBC |
UCHL3 |
10518943
14673145
15531586
20622874
22284438
23801757
25348397
25590432
27898060
9521656
9790970
|
N/A |
physical interaction |
ComPPI,OmniPath |
DLD |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PGD |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PLA2G2A |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
ENO1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
CDH1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
STIP1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
P4HB |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PEBP1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
TAGLN |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
RDX |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
GDI1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBA6 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
RAD51 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
ATM |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
CLPB |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
SUMO3 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
ZRANB2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
NEDD8 |
UCHL3 |
14525934
25348397
9790970
|
N/A |
two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid |
ComPPI,HPRD |
ACAA2 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
TPD52L1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM63 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
ZEB1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
YAP1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
TTC1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBE2A |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
COPS6 |
UCHL3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
CSE1L |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
MSN |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PJA1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBA1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PCMT1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBE4B |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBQLN1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM27 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PBX1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBE2V1 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
TSN |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
ATXN7L3 |
14525934
16713569
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid |
ComPPI,HPRD,IntAct |
UCHL3 |
NSG2 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
UCHL3 |
POGK |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
UCHL3 |
UBE2S |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
TRIM55 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
TRIM54 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
USP21 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
USP15 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
USP28 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
ZFYVE19 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
AHCYL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
USP48 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
USP9X |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
USP34 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
USP5 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
UBXN7 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
UBR1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
UNK |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
ATP6V1F |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
TTC9C |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
SULT1A1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
VPS33B |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
NT5DC1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
LONRF1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
ZMYM6 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
GPX4 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
HINT1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
ENO2 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
EZR |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
HSD17B10 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
ISYNA1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
NUP93 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
SMS |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
SOD2 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
TAGLN2 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
TPD52 |
25348397
|
N/A |
physical interaction |
ComPPI |
UCHL3 |
OTUB1 |
24234451
25348397
26752685
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
ZNF593 |
UCHL3 |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization