Gene Information gene info

GENE:UCHL3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UCHL3
FullNmae ubiquitin C-terminal hydrolase L3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12515
EnsembleID ENSG00000118939
Uniprot P15374

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UCHL3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UCHL3 GO:0004843,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006511,GO:0008233,GO:0016567,GO:0016579,GO:0016579,GO:0019784,GO:0030163,GO:0043130,GO:0043687

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 UCHL3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 UCHL3 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UCHL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UCHL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UCHL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UCHL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 UCHL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 UCHL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 UCHL3 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000345DEB UCHL3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB UCHL3 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002A79D1 UCHL3 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 UCHL3 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 UCHL3 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A UCHL3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF UCHL3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D UCHL3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 UCHL3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F UCHL3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C UCHL3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 UCHL3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000053B1E8 UCHL3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 UCHL3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB UCHL3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 UCHL3 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATM UCHL3 22135298 phosphorylation N/A PhosphoSite
COPS6 UCHL3 25361965 interaction type N/A PTMCode2
UCHL3 COPS6 25361965 interaction type N/A PTMCode2
NEDD8 UCHL3 25361965 interaction type N/A PTMCode2
UCHL3 NEDD8 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPRE1 UCHL3 25348397 N/A physical interaction ComPPI
USP20 UCHL3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPIB UCHL3 25348397 N/A physical interaction ComPPI
ZNRD2 UCHL3 25348397 N/A physical interaction ComPPI
BAG3 UCHL3 25348397 N/A physical interaction ComPPI
IMPDH2 UCHL3 25348397 N/A physical interaction ComPPI
SNRPD1 UCHL3 25348397 N/A physical interaction ComPPI
XIAP UCHL3 25348397 N/A physical interaction ComPPI
UBL7 UCHL3 25348397 N/A physical interaction ComPPI
SMAD1 UCHL3 21453705 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
ZYX UCHL3 25348397 N/A physical interaction ComPPI
COPS5 UCHL3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2L3 UCHL3 25348397 N/A physical interaction ComPPI
ARHGDIA UCHL3 25348397 N/A physical interaction ComPPI
UBB UCHL3 15531586 24234451 25348397 N/A x-ray crystallography ComPPI,IntAct
UBC UCHL3 10518943 14673145 15531586 20622874 22284438 23801757 25348397 25590432 27898060 9521656 9790970 N/A physical interaction ComPPI,OmniPath
DLD UCHL3 25348397 N/A physical interaction ComPPI
PGD UCHL3 25348397 N/A physical interaction ComPPI
PLA2G2A UCHL3 25348397 N/A physical interaction ComPPI
ENO1 UCHL3 25348397 N/A physical interaction ComPPI
CDH1 UCHL3 25348397 N/A physical interaction ComPPI
STIP1 UCHL3 25348397 N/A physical interaction ComPPI
P4HB UCHL3 25348397 N/A physical interaction ComPPI
PEBP1 UCHL3 25348397 N/A physical interaction ComPPI
TAGLN UCHL3 25348397 N/A physical interaction ComPPI
RDX UCHL3 25348397 N/A physical interaction ComPPI
GDI1 UCHL3 25348397 N/A physical interaction ComPPI
UBA6 UCHL3 25348397 N/A physical interaction ComPPI
RAD51 UCHL3 25348397 N/A physical interaction ComPPI
ATM UCHL3 25348397 N/A physical interaction ComPPI
CLPB UCHL3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUMO3 UCHL3 25348397 N/A physical interaction ComPPI
ZRANB2 UCHL3 25348397 N/A physical interaction ComPPI
NEDD8 UCHL3 14525934 25348397 9790970 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
ACAA2 UCHL3 25348397 N/A physical interaction ComPPI
TPD52L1 UCHL3 25348397 N/A physical interaction ComPPI
TRIM63 UCHL3 25348397 N/A physical interaction ComPPI
ZEB1 UCHL3 25348397 N/A physical interaction ComPPI
YAP1 UCHL3 25348397 N/A physical interaction ComPPI
TTC1 UCHL3 25348397 N/A physical interaction ComPPI
UBE2A UCHL3 25348397 N/A physical interaction ComPPI
COPS6 UCHL3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSE1L UCHL3 25348397 N/A physical interaction ComPPI
MSN UCHL3 25348397 N/A physical interaction ComPPI
PJA1 UCHL3 25348397 N/A physical interaction ComPPI
UBA1 UCHL3 25348397 N/A physical interaction ComPPI
PCMT1 UCHL3 25348397 N/A physical interaction ComPPI
UBE4B UCHL3 25348397 N/A physical interaction ComPPI
UBQLN1 UCHL3 25348397 N/A physical interaction ComPPI
TRIM27 UCHL3 25348397 N/A physical interaction ComPPI
PBX1 UCHL3 25348397 N/A physical interaction ComPPI
UBE2V1 UCHL3 25348397 N/A physical interaction ComPPI
TSN UCHL3 25348397 N/A physical interaction ComPPI
UCHL3 ATXN7L3 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UCHL3 NSG2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UCHL3 POGK 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UCHL3 UBE2S 25348397 N/A physical interaction ComPPI
UCHL3 TRIM55 25348397 N/A physical interaction ComPPI
UCHL3 TRIM54 25348397 N/A physical interaction ComPPI
UCHL3 USP21 25348397 N/A physical interaction ComPPI
UCHL3 USP15 25348397 N/A physical interaction ComPPI
UCHL3 USP28 25348397 N/A physical interaction ComPPI
UCHL3 ZFYVE19 25348397 N/A physical interaction ComPPI
UCHL3 AHCYL1 25348397 N/A physical interaction ComPPI
UCHL3 USP48 25348397 N/A physical interaction ComPPI
UCHL3 USP9X 25348397 N/A physical interaction ComPPI
UCHL3 USP34 25348397 N/A physical interaction ComPPI
UCHL3 USP5 25348397 N/A physical interaction ComPPI
UCHL3 UBXN7 25348397 N/A physical interaction ComPPI
UCHL3 UBR1 25348397 N/A physical interaction ComPPI
UCHL3 UNK 25348397 N/A physical interaction ComPPI
UCHL3 ATP6V1F 25348397 N/A physical interaction ComPPI
UCHL3 TTC9C 25348397 N/A physical interaction ComPPI
UCHL3 SULT1A1 25348397 N/A physical interaction ComPPI
UCHL3 VPS33B 25348397 N/A physical interaction ComPPI
UCHL3 NT5DC1 25348397 N/A physical interaction ComPPI
UCHL3 LONRF1 25348397 N/A physical interaction ComPPI
UCHL3 ZMYM6 25348397 N/A physical interaction ComPPI
UCHL3 GPX4 25348397 N/A physical interaction ComPPI
UCHL3 HINT1 25348397 N/A physical interaction ComPPI
UCHL3 ENO2 25348397 N/A physical interaction ComPPI
UCHL3 EZR 25348397 N/A physical interaction ComPPI
UCHL3 HSD17B10 25348397 N/A physical interaction ComPPI
UCHL3 ISYNA1 25348397 N/A physical interaction ComPPI
UCHL3 NUP93 25348397 N/A physical interaction ComPPI
UCHL3 SMS 25348397 N/A physical interaction ComPPI
UCHL3 SOD2 25348397 N/A physical interaction ComPPI
UCHL3 TAGLN2 25348397 N/A physical interaction ComPPI
UCHL3 TPD52 25348397 N/A physical interaction ComPPI
UCHL3 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
ZNF593 UCHL3 25348397 N/A physical interaction ComPPI

Visualization