Gene Information gene info

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GENE：NNMT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NNMT
FullNmae nicotinamide N-methyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7861
EnsembleID ENSG00000166741
Uniprot P40261

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NNMT pyroptosis 39706833 NNMT inhibited the stability of RBP4 mRNA via m6A modification, thereby preventing pyroptosis following PI(4,5)P2 treatment. retulator signature
NNMT mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NNMT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NNMT autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NNMT GO:0005829,GO:0005829,GO:0006769,GO:0008112,GO:0008112,GO:0008112,GO:0008112,GO:0009410,GO:0010243,GO:0030760,GO:0031100,GO:0032259,GO:0034356,GO:0045722,GO:0090312

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NNMT hsa:4837 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
NNMT hsa:4837 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR NNMT 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NNMT 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 NNMT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NNMT 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 NNMT 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000753AD NNMT 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 NNMT 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 NNMT 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC73 NNMT 25348397 N/A physical interaction ComPPI
ATF6 NNMT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BMF NNMT 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
APP NNMT 25348397 N/A physical interaction ComPPI
NNMT ADK 25348397 N/A physical interaction ComPPI

Visualization










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