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GENE：RIN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RIN1
FullNmae Ras and Rab interactor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18749
EnsembleID ENSG00000174791
Uniprot Q13671

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RIN1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RIN1 GO:0005085,GO:0005096,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0006897,GO:0007165,GO:0030139,GO:0031267

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RIN1 hsa:9610 path:hsa04014 Ras signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HRAS RIN1 10545207 11784866 23180781 physical association two hybrid,gst pull down,surface plasmon resonance InnateDB
RIN1 YWHAB 11784866 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
SMAD2 RIN1 18729074 23180781 physical association tandem affinity purification InnateDB

Source Target Pmid Interactiontype Methods Database
RIN1 EGFR 12783862 20542890 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
GATA1 RIN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RIN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PRKD1 RIN1 22135298 phosphorylation N/A PhosphoSite
PRKD2 RIN1 22135298 phosphorylation N/A PhosphoSite
HRAS RIN1 25361965 interaction type N/A PTMCode2
RIN1 HRAS 25361965 interaction type N/A PTMCode2
RAB5A RIN1 25361965 interaction type N/A PTMCode2
RIN1 RAB5A 25361965 interaction type N/A PTMCode2
YWHAE RIN1 25361965 interaction type N/A PTMCode2
RIN1 YWHAE 25361965 interaction type N/A PTMCode2
STAM2 RIN1 25361965 interaction type N/A PTMCode2
RIN1 STAM2 25361965 interaction type N/A PTMCode2
YWHAB RIN1 25361965 interaction type N/A PTMCode2
RIN1 YWHAB 25361965 interaction type N/A PTMCode2
EGFR RIN1 25361965 interaction type N/A PTMCode2
RIN1 EGFR 25361965 interaction type N/A PTMCode2
RIN1 ABL1 25361965 interaction type N/A PTMCode2
ABL1 RIN1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 RIN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZBED1 RIN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SEC23B RIN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SORBS3 RIN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRAS RIN1 25348397 N/A physical interaction ComPPI
LZTS2 RIN1 24234451 25348397 25416956 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YWHAG RIN1 25348397 N/A physical interaction ComPPI
RIN1 RAB5A 11703925 14525934 17403676 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
RIN1 RAB5B 11703925 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RIN1 HRAS 14525934 15886098 24234451 25348397 7862125 9144171 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,biochemical,genetic,in vitro,two hybrid ComPPI,HPRD,IntAct
RIN1 RRAS2 11788587 14525934 19060904 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,in vivo,two hybrid ComPPI,HPRD,IntAct
RIN1 YWHAZ 14525934 25348397 9144171 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RIN1 YWHAB 11784866 14525934 25348397 9144171 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RIN1 YWHAE 11784866 14525934 24234451 25348397 9144171 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RIN1 ABL2 14525934 15886098 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vivo ComPPI,HPRD,IntAct
RIN1 RALGDS 25348397 N/A physical interaction ComPPI
RIN1 AFDN 25348397 N/A physical interaction ComPPI
RIN1 STAM2 17403676 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
RIN1 EGFR 17403676 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
RIN1 SMAD2 18729074 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
RIN1 ERBB2 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
RIN1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
RIN1 CALCOCO2 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RIN1 ANKS1B 25348397 N/A physical interaction ComPPI
RIN1 COMT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIN1 ZWINT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIN1 ANKS1A 25348397 N/A physical interaction ComPPI
RIN1 NRAS 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 RRAS 25348397 N/A physical interaction ComPPI
RIN1 ISCA1 25348397 N/A physical interaction ComPPI
RIN1 YWHAH 25348397 N/A physical interaction ComPPI
RIN1 ABL1 14525934 15886098 24234451 25348397 9144171 phosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,protein kinase assay ComPPI,HPRD,IntAct
RIN1 RAP2B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RIN1 DPP8 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RIN1 TES 25348397 N/A physical interaction ComPPI
RIN1 CCM2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 KLHL12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 MDFI 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 CAPNS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 TFIP11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 TRAF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 CARD10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 TRIM7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 TRIM23 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 PLEKHG4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 TRIM27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 KRTAP15-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 PICK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 HMG20A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 EIF3F 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKD1 RIN1 11784866 18669648 21209314 27898060 inhibition N/A OmniPath
RIN1 EGFR 12783862 17403676 27898060 stimulant N/A OmniPath
ABL2 RIN1 15886098 15951569 18083107 19534553 20841568 27898060 9144171 stimulant N/A OmniPath
RIN1 ABL2 15886098 20841568 27898060 9144171 stimulant N/A OmniPath
HRAS RIN1 10545207 11784866 15031288 15886098 24441586 27898060 7862125 9144171 stimulant N/A OmniPath
RIN1 HRAS 10545207 11784866 15031288 15886098 24441586 27898060 7862125 9144171 inhibition,stimulant N/A OmniPath
ABL1 RIN1 15886098 15951569 18083107 19534553 27898060 9144171 stimulant N/A OmniPath
RIN1 NRAS 11784866 12574403 27898060 inhibition N/A OmniPath
CSNK2A1 RIN1 16497976 27898060 N/A N/A OmniPath
RALGDS RIN1 10545207 27898060 stimulant N/A OmniPath
AFDN RIN1 10545207 27898060 stimulant N/A OmniPath
RIN1 KRAS 11784866 27898060 stimulant N/A OmniPath
YWHAH RIN1 11784866 27898060 inhibition N/A OmniPath
RLF RIN1 10545207 27898060 stimulant N/A OmniPath

Visualization










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