Gene Information gene info

GENE:MTA3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTA3
FullNmae metastasis associated 1 family member 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23784
EnsembleID ENSG00000057935
Uniprot Q9BTC8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTA3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MTA3 GO:0000086,GO:0000122,GO:0003682,GO:0003713,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005654,GO:0005737,GO:0006338,GO:0010971,GO:0016575,GO:0016581,GO:0016581,GO:0016581,GO:0042659,GO:0042826,GO:0043231,GO:0043565,GO:0045892,GO:0045892,GO:0045893,GO:0046872,GO:0120325,GO:1904197,GO:1990739,GO:2000736

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MTA3 hsa:57504 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MTA3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 MTA3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MTA3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 MTA3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MTA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 MTA3 15169784 trascriptional regulation,stimulation inferred by curator TFlink
MTA1 MTA3 18719363 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C3AC1 MTA3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005A8ED MTA3 24293376 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000029D9F1 MTA3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 MTA3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 MTA3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA MTA3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 MTA3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 MTA3 19536157 21572407 23313552 23824327 24906430 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS0000306C70 MTA3 19536157 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004959F4 MTA3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 MTA3 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00001F373E MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 MTA3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 MTA3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000122F23 MTA3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GATAD2B MTA3 21258344 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L MTA3 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TCF19 MTA3 25348397 N/A physical interaction ComPPI
CDKN2C MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TUBB MTA3 24234451 25348397 26028330 association anti tag coimmunoprecipitation ComPPI,IntAct
TGFB1 MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KPNA1 MTA3 25348397 N/A physical interaction ComPPI
RAD21 MTA3 25348397 N/A physical interaction ComPPI
EHMT2 MTA3 24234451 25348397 26028330 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,chromatin immunoprecipitation assay ComPPI,IntAct
KDM5B MTA3 25348397 N/A physical interaction ComPPI
GRB2 MTA3 11483358 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JUN MTA3 25348397 N/A physical interaction ComPPI
TCF20 MTA3 25348397 N/A physical interaction ComPPI
FGFR2 MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FZR1 MTA3 25348397 N/A physical interaction ComPPI
CDH1 MTA3 24234451 25348397 25640309 physical association two hybrid,two hybrid array ComPPI,IntAct
PARP1 MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HMG20A MTA3 25348397 N/A physical interaction ComPPI
HNRNPL MTA3 25348397 N/A physical interaction ComPPI
ATM MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBBP4 MTA3 21258344 24234451 25348397 27705803 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
HNRNPA2B1 MTA3 25348397 N/A physical interaction ComPPI
SOX2 MTA3 25348397 N/A physical interaction ComPPI
HDAC2 MTA3 18451879 21258344 23752268 24234451 25348397 26028330 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK7 MTA3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MTA1 MTA3 21258344 24234451 25348397 26028330 association anti bait coimmunoprecipitation,physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
AURKA MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BAG4 MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTA3 CHD3 24234451 25348397 28977666 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTA3 MBD3 21258344 24234451 25123934 25348397 26028330 association anti bait coimmunoprecipitation,cross-linking study,pull down,physical interaction ComPPI,IntAct
MTA3 HDAC1 18451879 21258344 23752268 24234451 25348397 26028330 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
MTA3 BCL6 15454082 17545502 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MTA3 ZFPM2 25348397 N/A physical interaction ComPPI
MTA3 KDM1A 19703393 24234451 25348397 26028330 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTA3 CHD4 21258344 24234451 25348397 26028330 28977666 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTA3 ELAVL1 25348397 N/A physical interaction ComPPI
MTA3 CDK13 25348397 N/A physical interaction ComPPI
MTA3 MTA2 21258344 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTA3 RBBP7 21258344 24234451 25348397 26028330 27705803 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MTA3 CDK2AP1 24234451 25123934 25348397 association pull down,physical interaction ComPPI,IntAct
MTA3 GATAD2A 21258344 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTA3 MBD2 21258344 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTA3 HMG20B 25348397 N/A physical interaction ComPPI
MTA3 RCOR3 25348397 N/A physical interaction ComPPI
MTA3 ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTA3 PHF20L1 25348397 N/A physical interaction ComPPI
MTA3 CHD5 25348397 N/A physical interaction ComPPI
MTA3 AKT1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTA3 BCAR3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTA3 NOTCH2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTA3 NANOG 25348397 N/A physical interaction ComPPI
MTA3 IKZF1 25348397 N/A physical interaction ComPPI
MTA3 ZNF827 24234451 25150861 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTA3 FOXK2 25348397 N/A physical interaction ComPPI
MTA3 GATA3 24234451 25348397 26028330 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,chromatin immunoprecipitation assay ComPPI,IntAct
MTA3 BCLAF1 24234451 25348397 26028330 association anti tag coimmunoprecipitation ComPPI,IntAct
MTA3 THRAP3 24234451 25348397 26028330 association anti tag coimmunoprecipitation ComPPI,IntAct
MTA3 CDK8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
H3C1 MTA3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IGF1R MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AURKAIP1 MTA3 24234451 26028330 association chromatin immunoprecipitation assay IntAct
ZNF217 MTA3 24234451 26028330 association chromatin immunoprecipitation assay IntAct
NCOA3 MTA3 24234451 26028330 association chromatin immunoprecipitation assay IntAct
CDH2 MTA3 24234451 26028330 association chromatin immunoprecipitation assay IntAct
KMT2E MTA3 24234451 26028330 association chromatin immunoprecipitation assay IntAct
MTA3 ZEB2 24234451 26028330 association chromatin immunoprecipitation assay IntAct

Visualization