GENE：SLC44A1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SLC44A1 |
| FullNmae | solute carrier family 44 member 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18798 |
| EnsembleID | ENSG00000070214 |
| Uniprot | Q8WWI5 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SLC44A1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SLC44A1 | GO:0005654,GO:0005739,GO:0005741,GO:0005741,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0006656,GO:0015220,GO:0015220,GO:0015220,GO:0015220,GO:0015297,GO:0015871,GO:0015871,GO:0015871,GO:0015871,GO:0016020,GO:0016020,GO:0034228,GO:0034229,GO:0042426,GO:0055085,GO:0055085,GO:0055085,GO:0055085,GO:0070062,GO:0150104 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SLC44A1 | hsa:23446 | path:hsa05231 | Choline metabolism in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SLC44A1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | SLC44A1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | SLC44A1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | SLC44A1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | SLC44A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002C0FCB | SLC44A1 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00003380CC | SLC44A1 | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002E1509 | SLC44A1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | SLC44A1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | SLC44A1 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | SLC44A1 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00004C6C6F | SLC44A1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5E03 | SLC44A1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | SLC44A1 | 23824327 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000049FAE8 | SLC44A1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | SLC44A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CF3F0 | SLC44A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000157F5 | SLC44A1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | SLC44A1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | SLC44A1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077AED | SLC44A1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NUDT21 | SLC44A1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| CD9 | SLC44A1 | 23289620 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| PTH1R | SLC44A1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | SLC44A1 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | SLC44A1 | 25348397 | N/A | physical interaction | ComPPI |
| NT5E | SLC44A1 | 25348397 | N/A | physical interaction | ComPPI |
| SLC44A1 | KCNE3 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |