GENE：PRDM2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PRDM2 |
| FullNmae | PR/SET domain 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9347 |
| EnsembleID | ENSG00000116731 |
| Uniprot | Q13029 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PRDM2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PRDM2 | GO:0000122,GO:0000977,GO:0000977,GO:0000981,GO:0001227,GO:0001228,GO:0001228,GO:0003700,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005794,GO:0006338,GO:0006355,GO:0006357,GO:0008270,GO:0008340,GO:0032259,GO:0043565,GO:0045944,GO:0140949 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PRDM2 | hsa:7799 | path:hsa00310 | Lysine degradation - Homo sapiens (human) |
| PRDM2 | hsa:7799 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PRDM2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | PRDM2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | PRDM2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | PRDM2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YY1 | PRDM2 | 18488713 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PRDM2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | PRDM2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | PRDM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PRDM2 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000600E6 | PRDM2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000076E54 | PRDM2 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | PRDM2 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F4657 | PRDM2 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019D79B | PRDM2 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000364FEF | PRDM2 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001799A3 | PRDM2 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | PRDM2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | PRDM2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | PRDM2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | PRDM2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000083D87 | PRDM2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075ABF4 | PRDM2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | PRDM2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SRC | PRDM2 | 25348397 | N/A | physical interaction | ComPPI |
| RB1 | PRDM2 | 14525934 25348397 27898060 7538672 9223517 | N/A | two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| EP300 | PRDM2 | 25348397 | N/A | physical interaction | ComPPI |
| CTBP1 | PRDM2 | 25348397 | N/A | physical interaction | ComPPI |
| E2F1 | PRDM2 | 25348397 | N/A | physical interaction | ComPPI |
| PRDM2 | H3-4 | 14525934 14633678 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| PRDM2 | ESR1 | 10706618 14525934 15282304 19746436 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| PRDM2 | PGR | 25348397 | N/A | physical interaction | ComPPI |
| PRDM2 | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| PRDM2 | MDM2 | 25348397 | N/A | physical interaction | ComPPI |
| PRDM2 | SOD2 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| H3C1 | PRDM2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPU | PRDM2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| PRDM2 | H3C1 | 18022353 27898060 | inhibition | N/A | OmniPath |