Gene Information gene info

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GENE：FUCA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FUCA1
FullNmae alpha-L-fucosidase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4006
EnsembleID ENSG00000179163
Uniprot P04066

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FUCA1 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
FUCA1 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
FUCA1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FUCA1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FUCA1 GO:0004560,GO:0004560,GO:0004560,GO:0005515,GO:0005576,GO:0005737,GO:0005764,GO:0006004,GO:0006004,GO:0006027,GO:0016139,GO:0016139,GO:0019377,GO:0035578,GO:0043202,GO:0043231,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FUCA1 hsa:2517 path:hsa00511 Other glycan degradation - Homo sapiens (human)
FUCA1 hsa:2517 path:hsa04142 Lysosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR FUCA1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FUCA1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FUCA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FUCA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FUCA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FUCA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FUCA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FUCA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000005CF5F FUCA1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 FUCA1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 FUCA1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 FUCA1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VAV2 FUCA1 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKD1 FUCA1 25348397 N/A physical interaction ComPPI
CIB1 FUCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAXIP1 FUCA1 25348397 N/A physical interaction ComPPI
CUL3 FUCA1 25348397 N/A physical interaction ComPPI
UBQLN2 FUCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MARK2 FUCA1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BARD1 FUCA1 25348397 N/A physical interaction ComPPI
USP21 FUCA1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED10 FUCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APP FUCA1 25348397 N/A physical interaction ComPPI
TIPRL FUCA1 25348397 N/A physical interaction ComPPI

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