Gene Information gene info

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GENE：BUB3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BUB3
FullNmae BUB3 mitotic checkpoint protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1151
EnsembleID ENSG00000154473
Uniprot O43684

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BUB3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BUB3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BUB3 GO:0000776,GO:0000776,GO:0005515,GO:0005654,GO:0005654,GO:0005829,GO:0007094,GO:0007094,GO:0008608,GO:0033597,GO:0033597,GO:0034501,GO:0043130,GO:0051301,GO:0051321,GO:1990298

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BUB3 hsa:9184 path:hsa04110 Cell cycle - Homo sapiens (human)
BUB3 hsa:9184 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APC2 BUB3 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 26192618 7575488 8824189 9790499 interaction type N/A ACSN
BUB1 BUB3 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23180781 23197039 25416956 26192618 7575488 8824189 9790499 interaction type,physical association two hybrid ACSN,InnateDB
CDC20 BUB3 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 26192618 7575488 8824189 9790499 interaction type N/A ACSN
AURKB BUB3 12925766 14767480 15249581 16571674 17956729 26192618 interaction type N/A ACSN
BIRC5 BUB3 12925766 14767480 15249581 16571674 17956729 26192618 interaction type N/A ACSN
INCENP BUB3 12925766 14767480 15249581 16571674 17956729 26192618 interaction type N/A ACSN
BUB3 SMC3 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 26192618 7575488 8824189 9790499 interaction type N/A ACSN
SMAD2 BUB3 18729074 23180781 physical association tandem affinity purification InnateDB
SMAD3 BUB3 18729074 23180781 physical association tandem affinity purification InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 BUB3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 BUB3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 BUB3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 BUB3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF BUB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000A07C1 BUB3 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000EC1BE BUB3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 BUB3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000015188E BUB3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 BUB3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000149319 BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 BUB3 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 BUB3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000054DF42 BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000211070 BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A BUB3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000001C659 BUB3 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 BUB3 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 BUB3 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001E96DA BUB3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 BUB3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 BUB3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 BUB3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 BUB3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000246356 BUB3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD BUB3 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BUB1 BUB3 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PKM BUB3 22135298 phosphorylation N/A PhosphoSite
ANAPC1 BUB3 25361965 interaction type N/A PTMCode2
BUB3 ANAPC1 25361965 interaction type N/A PTMCode2
APC BUB3 25361965 interaction type N/A PTMCode2
BUB3 APC 25361965 interaction type N/A PTMCode2
CDC20 BUB3 25361965 interaction type N/A PTMCode2
BUB3 CDC20 25361965 interaction type N/A PTMCode2
SF3A2 BUB3 25361965 interaction type N/A PTMCode2
BUB3 SF3A2 25361965 interaction type N/A PTMCode2
ANAPC5 BUB3 25361965 interaction type N/A PTMCode2
BUB3 ANAPC5 25361965 interaction type N/A PTMCode2
BUB3 CDC26 25361965 interaction type N/A PTMCode2
CDC26 BUB3 25361965 interaction type N/A PTMCode2
BUB3 MAPRE1 25361965 interaction type N/A PTMCode2
MAPRE1 BUB3 25361965 interaction type N/A PTMCode2
BUB3 DYNLT3 25361965 interaction type N/A PTMCode2
DYNLT3 BUB3 25361965 interaction type N/A PTMCode2
BUB3 CDC23 25361965 interaction type N/A PTMCode2
CDC23 BUB3 25361965 interaction type N/A PTMCode2
CDC16 BUB3 25361965 interaction type N/A PTMCode2
BUB3 CDC16 25361965 interaction type N/A PTMCode2
USP11 BUB3 25361965 interaction type N/A PTMCode2
BUB3 USP11 25361965 interaction type N/A PTMCode2
BUB3 BUB1 25361965 interaction type N/A PTMCode2
USP7 BUB3 25361965 interaction type N/A PTMCode2
BUB3 USP7 25361965 interaction type N/A PTMCode2
BUB1B BUB3 25361965 interaction type N/A PTMCode2
BUB3 BUB1B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 BUB3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L BUB3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 BUB3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BUB3 PARP1 12011073 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
BUB3 BUB1 11283619 14525934 21988832 24234451 25348397 25416956 26496610 9660858 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
BUB3 BUB1B 14525934 19407811 21988832 22000412 24234451 25348397 25383541 25416956 25852190 26496610 9660858 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,mammalian protein protein interaction trap,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
BUB3 PARP2 12217960 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BUB3 HDAC2 25348397 N/A physical interaction,in vitro ComPPI
BUB3 HDAC1 14525934 15388328 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
BUB3 APC 25348397 N/A physical interaction ComPPI
BUB3 USP11 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 USP7 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 CDC20 21407176 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 CDC27 25348397 N/A physical interaction ComPPI
BUB3 HDGF 25348397 N/A physical interaction ComPPI
BUB3 ANAPC4 23288039 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 ELAVL1 25348397 N/A physical interaction ComPPI
BUB3 SF3A2 17332742 24234451 25348397 physical association affinity chromatography technology,physical interaction ComPPI,IntAct
BUB3 CUL3 25348397 N/A physical interaction ComPPI
BUB3 COPS5 25348397 N/A physical interaction ComPPI
BUB3 MAD2L1 25348397 N/A pull down,physical interaction,physical interaction ComPPI
BUB3 SMAD2 25348397 N/A physical interaction,tandem affinity purification ComPPI
BUB3 SMAD3 25348397 N/A physical interaction,tandem affinity purification ComPPI
BUB3 TOP1 25348397 N/A physical interaction ComPPI
BUB3 ZNF207 21988832 22365833 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
BUB3 SEPTIN2 25348397 N/A physical interaction ComPPI
BUB3 FN1 25348397 N/A physical interaction ComPPI
BUB3 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
BUB3 NKAP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BUB3 ITGA4 25348397 N/A physical interaction ComPPI
BUB3 EGFR 25348397 N/A physical interaction ComPPI
BUB3 SUGT1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BUB3 CPNE1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BUB3 UBA1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BUB3 RPL37A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BUB3 THRA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BUB3 EXOC3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BUB3 WBP4 16055720 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
BUB3 CLIP1 25348397 N/A physical interaction ComPPI
BUB3 RPA3 25348397 N/A physical interaction ComPPI
BUB3 RPA2 25348397 N/A physical interaction ComPPI
BUB3 RPA1 25348397 N/A physical interaction ComPPI
BUB3 HUWE1 25348397 N/A physical interaction ComPPI
BUB3 PSTPIP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BUB3 CCT7 25348397 N/A physical interaction ComPPI
BUB3 CCT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 BTBD10 25348397 N/A physical interaction ComPPI
BUB3 KCTD20 25348397 N/A physical interaction ComPPI
BUB3 ZFC3H1 25348397 N/A physical interaction ComPPI
BUB3 ANAPC16 25348397 N/A physical interaction ComPPI
BUB3 UBR5 25348397 N/A physical interaction ComPPI
BUB3 APEX1 25348397 N/A physical interaction ComPPI
BUB3 EEF1AKNMT 25348397 N/A physical interaction ComPPI
BUB3 HK2 25348397 N/A physical interaction ComPPI
BUB3 NTRK1 25348397 N/A physical interaction ComPPI
BUB3 XPO1 25348397 N/A physical interaction ComPPI
BUB3 H3C1 25348397 N/A physical interaction ComPPI
BUB3 DNM2 25348397 N/A physical interaction ComPPI
BUB3 RNPS1 25348397 N/A physical interaction ComPPI
BUB3 CCT4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 CCT5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 INTS7 25348397 N/A physical interaction ComPPI
BUB3 RASIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB3 KIAA1109 25348397 N/A physical interaction ComPPI
BUB3 KPNB1 25348397 N/A physical interaction ComPPI
BUB3 YBX1 25348397 N/A physical interaction ComPPI
BUB3 MCM2 25348397 N/A physical interaction ComPPI
BUB3 GLI1 25348397 N/A physical interaction ComPPI
BUB3 BOP1 25348397 N/A physical interaction ComPPI
BUB3 PES1 25348397 N/A physical interaction ComPPI
BUB3 CCT6B 25348397 N/A physical interaction ComPPI
BUB3 CCT3 25348397 N/A physical interaction ComPPI
BUB3 KNL1 25348397 N/A physical interaction ComPPI
BUB3 CDC23 20360068 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
BUB3 CCT6A 25348397 N/A physical interaction ComPPI
BUB3 ACTBL2 25348397 N/A physical interaction ComPPI
BUB3 CCT8 25348397 N/A physical interaction ComPPI
BUB3 ACTA2 25348397 N/A physical interaction ComPPI
BUB3 LZTFL1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
BUB3 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
BUB3 DNM1L 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
BUB3 HSD17B10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
BUB3 UBE2A 25348397 N/A physical interaction ComPPI
BUB3 BRCA1 25348397 N/A physical interaction ComPPI
BUB3 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BUB3 ADRM1 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
BUB3 DYNLT3 17289665 24234451 25348397 27898060 N/A pull down ComPPI,IntAct,OmniPath
BUB3 ANAPC1 20360068 24234451 25348397 association tandem affinity purification ComPPI,IntAct
BUB3 ANAPC5 20360068 24234451 25348397 association tandem affinity purification ComPPI,IntAct
BUB3 CDC16 20360068 24234451 25348397 association tandem affinity purification ComPPI,IntAct
BUB3 CDC26 20360068 24234451 25348397 association tandem affinity purification ComPPI,IntAct
BUB3 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BUB3 MAP1LC3B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BUB3 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BUB3 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
BUB3 CHEK2 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
BUB3 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BUB3 TP53BP1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
TCP1 BUB3 25348397 N/A physical interaction ComPPI
BUB3 MXD3 10704439 15644329 17227844 17406666 20498086 27898060 N/A N/A OmniPath
BUB3 PPP1R7 23894419 27898060 N/A N/A OmniPath

Visualization










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