GENE:AGK
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AGK |
| FullNmae | acylglycerol kinase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21869 |
| EnsembleID | ENSG00000006530 |
| Uniprot | Q53H12 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AGK | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AGK | GO:0001729,GO:0004143,GO:0004143,GO:0005515,GO:0005524,GO:0005739,GO:0005739,GO:0005741,GO:0005743,GO:0005758,GO:0005829,GO:0031966,GO:0042721,GO:0042721,GO:0043231,GO:0045039,GO:0046486,GO:0046513,GO:0046834,GO:0047620,GO:0047620,GO:0102773 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AGK | hsa:55750 | path:hsa00561 | Glycerolipid metabolism - Homo sapiens (human) |
| AGK | hsa:55750 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | AGK | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | AGK | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | AGK | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | AGK | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | AGK | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | AGK | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | AGK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00005651EE | AGK | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000451A1 | AGK | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000072E4C | AGK | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023F8DA | AGK | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F3336 | AGK | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002971AB | AGK | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B0E50 | AGK | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F1B8C | AGK | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000022AAA | AGK | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | AGK | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000393C7 | AGK | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BMI1 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| NDUFAF4 | AGK | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CUL3 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| WWP2 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| MYC | AGK | 21150319 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| DCTN1 | AGK | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| CFTR | AGK | 25348397 | N/A | physical interaction | ComPPI |
| NPHP1 | AGK | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| RNF2 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| MED23 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| PDLIM1 | AGK | 14525934 16169070 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| PRKN | AGK | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| AP3S1 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| HCK | AGK | 14525934 16169070 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| RAB18 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| AGK | RYK | 25348397 | N/A | physical interaction | ComPPI |
| AGK | MRPL58 | 20186120 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AGK | AGO4 | 19167051 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AGK | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
| AGK | TCTN2 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| AGK | FBF1 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| AGK | POC5 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| AGK | OTUB1 | 24234451 25348397 26752685 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AGK | COQ9 | 25348397 | N/A | physical interaction | ComPPI |
| AGK | NDUFA4 | 25348397 | N/A | physical interaction | ComPPI |
| AGK | TIMM10B | 25348397 | N/A | physical interaction | ComPPI |
| AGK | HCCS | 25348397 | N/A | physical interaction | ComPPI |
| AGK | TIMM10 | 25348397 | N/A | physical interaction | ComPPI |
| AGK | TIMM29 | 25348397 | N/A | physical interaction | ComPPI |
| AGK | ATP12A | 25348397 | N/A | physical interaction | ComPPI |
| AGK | RSPRY1 | 25348397 | N/A | physical interaction | ComPPI |
| AGK | RIPK4 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| AGK | COX6B1 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PCSK9 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| SNX4 | AGK | 14525934 16169070 | N/A | two hybrid | HPRD |
