GENE：ARG2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ARG2 |
| FullNmae | arginase 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:664 |
| EnsembleID | ENSG00000081181 |
| Uniprot | P78540 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ARG2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ARG2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ARG2 | GO:0000050,GO:0001657,GO:0002250,GO:0002829,GO:0004053,GO:0004053,GO:0005515,GO:0005737,GO:0005739,GO:0005759,GO:0006809,GO:0006941,GO:0019547,GO:0030145,GO:0032651,GO:0032696,GO:0032700,GO:0032720,GO:0045087,GO:0071641,GO:0071644,GO:0071650,GO:1900425,GO:1903426,GO:1905403,GO:2000562,GO:2000774 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ARG2 | hsa:384 | path:hsa00220 | Arginine biosynthesis - Homo sapiens (human) |
| ARG2 | hsa:384 | path:hsa00330 | Arginine and proline metabolism - Homo sapiens (human) |
| ARG2 | hsa:384 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| ARG2 | hsa:384 | path:hsa01230 | Biosynthesis of amino acids - Homo sapiens (human) |
| ARG2 | hsa:384 | path:hsa04148 | Efferocytosis - Homo sapiens (human) |
| ARG2 | hsa:384 | path:hsa05146 | Amoebiasis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ARG2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | ARG2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ARG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ARG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ARG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ARG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ARG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| AR | ARG2 | 20711410 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ARG1 | ARG2 | 11849441 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| ARG2 | CPT2 | 25348397 | N/A | physical interaction | ComPPI |
| ARG2 | STK11 | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| ARG2 | MATN4 | 25348397 | N/A | physical interaction | ComPPI |
| HSCB | ARG2 | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |