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GENE：BTG1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BTG1
FullNmae BTG anti-proliferation factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1130
EnsembleID ENSG00000133639
Uniprot P62324

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BTG1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BTG1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BTG1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BTG1 GO:0003712,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0006355,GO:0008283,GO:0008285,GO:0008285,GO:0016477,GO:0019899,GO:0019900,GO:0030308,GO:0045603,GO:0045663,GO:0045663,GO:0045766,GO:0045930,GO:2000271

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BTG1 hsa:694 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BTG1 CNOT8 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR BTG1 16281084 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
E2F4 BTG1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 BTG1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 BTG1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXO3 BTG1 18226221 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 BTG1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 BTG1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 BTG1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 BTG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HLX BTG1 22897850 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 BTG1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE BTG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000508C13 BTG1 22012620 22020335 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000006FDD4 BTG1 23313552 25416803 25936765 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00001A4ABF BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000096022 BTG1 25416803 25449431 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000007340 BTG1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 BTG1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 BTG1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 BTG1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 BTG1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004959F4 BTG1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C BTG1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001941B8 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 BTG1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B BTG1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 BTG1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A9CF BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002E177F BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC BTG1 23313552 25416803 28193514 mrna cleavage,inhibition quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000315338 BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000060B2B BTG1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 BTG1 22135298 phosphorylation N/A PhosphoSite
BTG1 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 BTG1 25361965 interaction type N/A PTMCode2
BTG1 HOXB9 25361965 interaction type N/A PTMCode2
HOXB9 BTG1 25361965 interaction type N/A PTMCode2
BTG1 CNOT7 25361965 interaction type N/A PTMCode2
CNOT7 BTG1 25361965 interaction type N/A PTMCode2
MYOD1 BTG1 25361965 interaction type N/A PTMCode2
BTG1 MYOD1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 BTG1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXB9 BTG1 10617598 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
CDKN2D BTG1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
SKP1 BTG1 25348397 N/A physical interaction ComPPI
LIG4 BTG1 25348397 N/A physical interaction ComPPI
BTG1 PRMT1 11856371 14525934 14734530 25348397 8663146 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
BTG1 CNOT8 11136725 14525934 16189514 21900206 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,HPRD,IntAct
BTG1 CNOT7 11136725 21900206 24234451 25348397 27107012 physical association two hybrid,pull down,physical interaction,split luciferase complementation ComPPI,IntAct
BTG1 TUBA1A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BTG1 XRCC6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BTG1 CUL1 25348397 N/A physical interaction ComPPI
BTG1 SKP2 25348397 N/A physical interaction ComPPI
BTG1 FBXL5 25348397 N/A physical interaction ComPPI
BTG1 FBXW7 25348397 N/A physical interaction ComPPI
BTG1 BTRC 25348397 N/A physical interaction ComPPI
BTG1 FBXW11 25348397 N/A physical interaction ComPPI
BTG1 FBXW2 25348397 N/A physical interaction ComPPI
BTG1 FBXL3 25348397 N/A physical interaction ComPPI
BTG1 RNF181 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BTG1 FADD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BTG1 RARA 14525934 15674337 N/A experimental interaction detection HPRD
BTG1 THRA 14525934 15674337 N/A experimental interaction detection HPRD
BTG1 THRB 14525934 15674337 N/A experimental interaction detection HPRD
CCNA2 BTG1 14525934 9820826 N/A experimental interaction detection HPRD
CDK2 BTG1 27898060 9820826 N/A N/A OmniPath
BTG1 HOXB9 10617598 27898060 stimulant N/A OmniPath

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