GENE：CD3D
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CD3D |
| FullNmae | CD3 delta subunit of T-cell receptor complex |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1673 |
| EnsembleID | ENSG00000167286 |
| Uniprot | P04234 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CD3D | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CD3D | GO:0002250,GO:0004888,GO:0004888,GO:0005515,GO:0005737,GO:0005886,GO:0005886,GO:0005886,GO:0007166,GO:0007166,GO:0009897,GO:0030669,GO:0042101,GO:0042105,GO:0042105,GO:0042105,GO:0042105,GO:0042802,GO:0045059,GO:0045059,GO:0046631,GO:0050852 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CD3D | hsa:915 | path:hsa04640 | Hematopoietic cell lineage - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa04658 | Th1 and Th2 cell differentiation - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa04659 | Th17 cell differentiation - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa04660 | T cell receptor signaling pathway - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa05142 | Chagas disease - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa05162 | Measles - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa05166 | Human T-cell leukemia virus 1 infection - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa05169 | Epstein-Barr virus infection - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human) |
| CD3D | hsa:915 | path:hsa05340 | Primary immunodeficiency - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000075C1E1 | CD3D | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | CD3D | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032AE90 | CD3D | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | CD3D | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | CD3D | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000148B91 | CD3D | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | CD3D | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | CD3D | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EBD4B | CD3D | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D986D | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000331800 | CD3D | 23824327 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0920 | CD3D | 23824327 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000003FD55 | CD3D | 23824327 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004900F1 | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010BD8D | CD3D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016D2D4 | CD3D | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AC389 | CD3D | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000E1E9E | CD3D | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | CD3D | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | CD3D | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000047A67D | CD3D | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DERL1 | CD3D | 25361965 | interaction type | N/A | PTMCode2 |
| CD3D | DERL1 | 25361965 | interaction type | N/A | PTMCode2 |
| AMFR | CD3D | 25361965 | interaction type | N/A | PTMCode2 |
| CD3D | AMFR | 25361965 | interaction type | N/A | PTMCode2 |
| CD8A | CD3D | 25361965 | interaction type | N/A | PTMCode2 |
| CD3D | CD8A | 25361965 | interaction type | N/A | PTMCode2 |
| CD3D | CD3E | 25361965 | interaction type | N/A | PTMCode2 |
| CD3E | CD3D | 25361965 | interaction type | N/A | PTMCode2 |
| CD3D | CD247 | 25361965 | interaction type | N/A | PTMCode2 |
| CD247 | CD3D | 25361965 | interaction type | N/A | PTMCode2 |
| CD3D | FYN | 25361965 | interaction type | N/A | PTMCode2 |
| FYN | CD3D | 25361965 | interaction type | N/A | PTMCode2 |
| CANX | CD3D | 25361965 | interaction type | N/A | PTMCode2 |
| CD3D | CANX | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SGTB | CD3D | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VCP | CD3D | 25348397 | N/A | physical interaction | ComPPI |
| CD3E | CD3D | 14525934 20890284 24234451 25348397 9485181 9582308 | association | anti bait coimmunoprecipitation,experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,IntAct |
| UBB | CD3D | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
| UBC | CD3D | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
| RPS27A | CD3D | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
| UBA52 | CD3D | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
| CANX | CD3D | 14525934 24234451 25241761 25348397 27898060 8278814 8621641 | physical association | experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct,OmniPath |
| KCNA3 | CD3D | 25348397 | N/A | physical interaction | ComPPI |
| CD247 | CD3D | 14525934 25348397 9485181 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CD3D | CD8A | 12215456 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CD3D | CD3G | 14525934 25348397 9485181 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CD3D | AP2M1 | 14525934 15778375 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
| CD3D | HERPUD1 | 14525934 18307982 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CD3D | DERL1 | 25348397 | N/A | physical interaction | ComPPI |
| CD3D | AMFR | 16407162 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD3D | ERLIN2 | 25348397 | N/A | physical interaction | ComPPI |
| CD3D | PDIA2 | 25348397 | N/A | physical interaction | ComPPI |
| CD3D | UBQLN1 | 25348397 | N/A | physical interaction | ComPPI |
| CD3D | NR3C1 | 16888650 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |