GENE：CITED2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CITED2 |
| FullNmae | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1987 |
| EnsembleID | ENSG00000164442 |
| Uniprot | Q99967 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CITED2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CITED2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CITED2 | GO:0000122,GO:0000785,GO:0001570,GO:0001666,GO:0001666,GO:0001829,GO:0001843,GO:0001889,GO:0001892,GO:0001947,GO:0002089,GO:0002244,GO:0003151,GO:0003156,GO:0003197,GO:0003682,GO:0003713,GO:0003713,GO:0003714,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0007179,GO:0007368,GO:0007417,GO:0007422,GO:0007507,GO:0007507,GO:0007530,GO:0007530,GO:0008283,GO:0008584,GO:0009612,GO:0010628,GO:0010629,GO:0019904,GO:0021602,GO:0022409,GO:0030336,GO:0030511,GO:0030851,GO:0032991,GO:0034405,GO:0035035,GO:0035360,GO:0035802,GO:0035914,GO:0043066,GO:0043231,GO:0043627,GO:0045787,GO:0045892,GO:0045892,GO:0045893,GO:0045893,GO:0045944,GO:0045944,GO:0046332,GO:0046697,GO:0048536,GO:0048538,GO:0048596,GO:0048821,GO:0050693,GO:0060044,GO:0060136,GO:0060349,GO:0060412,GO:0060971,GO:0060972,GO:0061156,GO:0061308,GO:0061428,GO:0061629,GO:0070986,GO:0090398,GO:0140677,GO:1900164,GO:2000020 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CITED2 | hsa:10370 | path:hsa04137 | Mitophagy - animal - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CITED2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | CITED2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CITED2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | CITED2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | CITED2 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CITED2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CITED2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | CITED2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ELK1 | CITED2 | 16740701 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HDAC9 | CITED2 | 18054336 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NR5A1 | CITED2 | 18984668 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARA | CITED2 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000272039 | CITED2 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS0000237AF9 | CITED2 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000077AED | CITED2 | 21572407 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C48FA | CITED2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000308E4D | CITED2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000246356 | CITED2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000025EABA | CITED2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | CITED2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B13F | CITED2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002AAD6B | CITED2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052EA98 | CITED2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009C45F | CITED2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC379 | CITED2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | CITED2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000157F5 | CITED2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | CITED2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAPK1 | CITED2 | 25348397 | N/A | physical interaction | ComPPI |
| TBP | CITED2 | 25348397 | N/A | physical interaction | ComPPI |
| CREBBP | CITED2 | 14525934 25348397 9887100 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| SMAD2 | CITED2 | 25348397 | N/A | physical interaction | ComPPI |
| EP300 | CITED2 | 12586840 12778114 14525934 24234451 25348397 9887100 | physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| SMAD3 | CITED2 | 16619037 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| HIF1A | CITED2 | 12778114 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| TFAP2A | CITED2 | 11694877 11744733 12586840 14525934 24234451 25348397 27898060 | physical association | two hybrid,experimental interaction detection,far western blotting,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| CITED2 | TFAP2C | 11744733 12586840 14525934 24234451 25348397 | physical association | two hybrid,experimental interaction detection,far western blotting,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| CITED2 | LHX2 | 10593900 14525934 25348397 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| CITED2 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| CITED2 | FBXL5 | 25348397 | N/A | physical interaction | ComPPI |
| CITED2 | HNF4A | 17932483 24234451 25348397 27898060 | colocalization,physical association | two hybrid,pull down,fluorescence microscopy | ComPPI,IntAct,OmniPath |