Gene Information gene info

GENE:EIF1AX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF1AX
FullNmae eukaryotic translation initiation factor 1A X-linked
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3250
EnsembleID ENSG00000173674
Uniprot P47813

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF1AX immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF1AX GO:0000049,GO:0003723,GO:0003743,GO:0005515,GO:0005737,GO:0005829,GO:0006413,GO:0006413,GO:0008135,GO:0016282,GO:0016282,GO:0033290,GO:0042255,GO:0043614

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG EIF1AX 20098747 23180781 physical association protein array InnateDB
APP EIF1AX 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 EIF1AX 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 EIF1AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EIF1AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EIF1AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 EIF1AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EIF1AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 EIF1AX 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000035CC3E EIF1AX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005D4F5 EIF1AX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007D64A EIF1AX 20371350 21572407 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000009262D EIF1AX 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 EIF1AX 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 EIF1AX 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D EIF1AX 22012620 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029D793 EIF1AX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A EIF1AX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C EIF1AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 EIF1AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 EIF1AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 EIF1AX 20371350 21572407 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000040EE1D EIF1AX 20371350 21572407 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041CB9C EIF1AX 20371350 21572407 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000171CD1 EIF1AX 20371350 21572407 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000D2680 EIF1AX 20371350 21572407 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000024CEE0 EIF1AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000034B6F5 EIF1AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F EIF1AX 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D EIF1AX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 EIF1AX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F7766 EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D EIF1AX 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 EIF1AX 22012620 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032FC1A EIF1AX 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041E11D EIF1AX 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000939AF EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000054A671 EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000058276F EIF1AX 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075D860 EIF1AX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE EIF1AX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA EIF1AX 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF3J EIF1AX 25361965 interaction type N/A PTMCode2
EIF1AX EIF3J 25361965 interaction type N/A PTMCode2
EIF1AX EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF1AX 25361965 interaction type N/A PTMCode2
EIF2S1 EIF1AX 25361965 interaction type N/A PTMCode2
EIF1AX EIF2S1 25361965 interaction type N/A PTMCode2
EIF3C EIF1AX 25361965 interaction type N/A PTMCode2
EIF1AX EIF3C 25361965 interaction type N/A PTMCode2
EIF2S2 EIF1AX 25361965 interaction type N/A PTMCode2
EIF1AX EIF2S2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF1B EIF1AX 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IPO13 EIF1AX 11447110 14525934 21139563 23435562 24234451 25348397 physical association experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,competition binding,in vitro,thermal shift binding ComPPI,HPRD,IntAct
LRATD2 EIF1AX 25348397 N/A physical interaction ComPPI
NPM1 EIF1AX 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFB1 EIF1AX 25348397 N/A physical interaction ComPPI
TRAF6 EIF1AX 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RAN EIF1AX 23435562 24234451 25348397 physical association molecular sieving,x-ray crystallography,thermal shift binding ComPPI,IntAct
EIF5 EIF1AX 10982835 14525934 24234451 25348397 27898060 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
RPL10 EIF1AX 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCD1 EIF1AX 25348397 N/A physical interaction ComPPI
EIF5B EIF1AX 12514125 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SUB1 EIF1AX 25348397 N/A physical interaction ComPPI
LCMT1 EIF1AX 25348397 N/A physical interaction ComPPI
EIF6 EIF1AX 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF2S1 EIF1AX 12514125 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EIF3C EIF1AX 12514125 14525934 23623729 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RAB3IL1 EIF1AX 25348397 N/A physical interaction ComPPI
CRACR2A EIF1AX 25348397 N/A physical interaction ComPPI
VHL EIF1AX 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PINX1 EIF1AX 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPB1 EIF1AX 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
ASGR2 EIF1AX 25348397 N/A physical interaction ComPPI
EIF1AX IKBKG 25348397 N/A physical interaction ComPPI
EIF1AX DCC 25348397 N/A physical interaction ComPPI
EIF1AX ELAVL1 25348397 N/A physical interaction ComPPI
EIF1AX APP 25348397 N/A physical interaction ComPPI
EIF1AX FLII 25348397 N/A physical interaction ComPPI
EIF1AX ADSL 25348397 N/A physical interaction ComPPI
EIF1AX BPGM 25348397 N/A physical interaction ComPPI
EIF1AX KCTD17 25348397 N/A physical interaction ComPPI
EIF1AX CRHBP 25348397 N/A physical interaction ComPPI
EIF1AX ERBB3 25348397 N/A physical interaction ComPPI
EIF1AX MRM1 25348397 N/A physical interaction ComPPI
EIF1AX NAP1L1 25348397 N/A physical interaction ComPPI
EIF1AX TFG 25348397 N/A physical interaction ComPPI
EIF1AX SGO2 25348397 N/A physical interaction ComPPI
EIF1AX AMDHD1 25348397 N/A physical interaction ComPPI
EIF1AX ACAA1 25348397 N/A physical interaction ComPPI
EIF1AX CDK4 25348397 N/A physical interaction ComPPI
EIF1AX EIF1AY 25348397 N/A physical interaction ComPPI
EIF1AX NCR3LG1 25348397 N/A physical interaction ComPPI
EIF1AX PSG1 25348397 N/A physical interaction ComPPI
EIF1AX WFDC2 25348397 N/A physical interaction ComPPI
EIF1AX POF1B 25348397 N/A physical interaction ComPPI
EIF1AX PDK3 25348397 N/A physical interaction ComPPI
EIF1AX SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF1AX EIF3A 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EIF1AX RFPL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BBOX1 EIF1AX 25348397 N/A physical interaction ComPPI
IKBKG EIF1AX 20098747 27898060 N/A N/A OmniPath

Visualization