GENE:EIF1AX
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | EIF1AX |
FullNmae | eukaryotic translation initiation factor 1A X-linked |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:3250 |
EnsembleID | ENSG00000173674 |
Uniprot | P47813 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
EIF1AX | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
EIF1AX | GO:0000049,GO:0003723,GO:0003743,GO:0005515,GO:0005737,GO:0005829,GO:0006413,GO:0006413,GO:0008135,GO:0016282,GO:0016282,GO:0033290,GO:0042255,GO:0043614 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | EIF1AX | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | EIF1AX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | EIF1AX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | EIF1AX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | EIF1AX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | EIF1AX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000003ABC4 | EIF1AX | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000035CC3E | EIF1AX | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000005D4F5 | EIF1AX | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000007D64A | EIF1AX | 20371350 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000009262D | EIF1AX | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000272039 | EIF1AX | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000277201 | EIF1AX | 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000013E79D | EIF1AX | 22012620 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000029D793 | EIF1AX | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000017EA6A | EIF1AX | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003003B4 | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000000C73C | EIF1AX | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000250A40 | EIF1AX | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000292B1 | EIF1AX | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000F0F49 | EIF1AX | 20371350 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000040EE1D | EIF1AX | 20371350 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000041CB9C | EIF1AX | 20371350 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000171CD1 | EIF1AX | 20371350 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000D2680 | EIF1AX | 20371350 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000024CEE0 | EIF1AX | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000034B6F5 | EIF1AX | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000061E50F | EIF1AX | 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005D986D | EIF1AX | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000508C13 | EIF1AX | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001310DE | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000081D1E | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000F7766 | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000043D2C1 | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008AA34 | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000118224 | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C02E4 | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070B1D | EIF1AX | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001BCAC5 | EIF1AX | 22012620 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000032FC1A | EIF1AX | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000041E11D | EIF1AX | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000939AF | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002075FA | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008F0CF | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000435A77 | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000054A671 | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000080D0A | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000058276F | EIF1AX | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075D860 | EIF1AX | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002F5FEE | EIF1AX | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C5BAA | EIF1AX | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
EIF3J | EIF1AX | 25361965 | interaction type | N/A | PTMCode2 |
EIF1AX | EIF3J | 25361965 | interaction type | N/A | PTMCode2 |
EIF1AX | EIF1 | 25361965 | interaction type | N/A | PTMCode2 |
EIF1 | EIF1AX | 25361965 | interaction type | N/A | PTMCode2 |
EIF2S1 | EIF1AX | 25361965 | interaction type | N/A | PTMCode2 |
EIF1AX | EIF2S1 | 25361965 | interaction type | N/A | PTMCode2 |
EIF3C | EIF1AX | 25361965 | interaction type | N/A | PTMCode2 |
EIF1AX | EIF3C | 25361965 | interaction type | N/A | PTMCode2 |
EIF2S2 | EIF1AX | 25361965 | interaction type | N/A | PTMCode2 |
EIF1AX | EIF2S2 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
EIF1B | EIF1AX | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
IPO13 | EIF1AX | 11447110 14525934 21139563 23435562 24234451 25348397 | physical association | experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,competition binding,in vitro,thermal shift binding | ComPPI,HPRD,IntAct |
LRATD2 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
NPM1 | EIF1AX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TGFB1 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
TRAF6 | EIF1AX | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
RAN | EIF1AX | 23435562 24234451 25348397 | physical association | molecular sieving,x-ray crystallography,thermal shift binding | ComPPI,IntAct |
EIF5 | EIF1AX | 10982835 14525934 24234451 25348397 27898060 | physical association | two hybrid,coimmunoprecipitation,experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,IntAct,OmniPath |
RPL10 | EIF1AX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SMARCD1 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
EIF5B | EIF1AX | 12514125 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD |
SUB1 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
LCMT1 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
EIF6 | EIF1AX | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
EIF2S1 | EIF1AX | 12514125 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
EIF3C | EIF1AX | 12514125 14525934 23623729 24234451 25348397 | association | experimental interaction detection,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
RAB3IL1 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
CRACR2A | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
VHL | EIF1AX | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
PINX1 | EIF1AX | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
HSPB1 | EIF1AX | 24234451 25277244 25348397 | physical association | reverse ras recruitment system,physical interaction | ComPPI,IntAct |
ASGR2 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | IKBKG | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | DCC | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | APP | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | FLII | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | ADSL | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | BPGM | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | KCTD17 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | CRHBP | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | ERBB3 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | MRM1 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | NAP1L1 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | TFG | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | SGO2 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | AMDHD1 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | ACAA1 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | CDK4 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | EIF1AY | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | NCR3LG1 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | PSG1 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | WFDC2 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | POF1B | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | PDK3 | 25348397 | N/A | physical interaction | ComPPI |
EIF1AX | SOD1 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
EIF1AX | EIF3A | 23623729 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
EIF1AX | RFPL3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
BBOX1 | EIF1AX | 25348397 | N/A | physical interaction | ComPPI |
IKBKG | EIF1AX | 20098747 27898060 | N/A | N/A | OmniPath |