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GENE：GAP43

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GAP43
FullNmae growth associated protein 43
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4140
EnsembleID ENSG00000172020
Uniprot P17677

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GAP43 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GAP43 GO:0001786,GO:0005515,GO:0005516,GO:0005737,GO:0005886,GO:0005886,GO:0005886,GO:0007205,GO:0009611,GO:0014069,GO:0016198,GO:0030425,GO:0031103,GO:0031527,GO:0032584,GO:0035727,GO:0040008,GO:0042246,GO:0043204,GO:0045165,GO:0048708,GO:0051489,GO:0060019,GO:0098793,GO:0098982,GO:0099150,GO:1901981

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GAP43 PRKCB 20005715 interaction type N/A PSP
GAP43 CSNK2A1 20005715 interaction type N/A PSP
GAP43 PRKCD 20005715 interaction type N/A PSP
GAP43 CSNK2A1 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR GAP43 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 GAP43 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GAP43 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 GAP43 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA GAP43 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GAP43 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GAP43 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GAP43 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GAP43 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GAP43 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 GAP43 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D4175 GAP43 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE GAP43 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E GAP43 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F GAP43 25416803 27495233 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKCD GAP43 25361965 interaction type N/A PTMCode2
GAP43 PRKCD 25361965 interaction type N/A PTMCode2
ELAVL2 GAP43 25361965 interaction type N/A PTMCode2
GAP43 ELAVL2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CALM1 GAP43 25348397 N/A two hybrid,physical interaction,physical interaction ComPPI
MED21 GAP43 25348397 N/A physical interaction ComPPI
PRKCD GAP43 14525934 24234451 25348397 27898060 9139733 phosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
ELAVL4 GAP43 12034726 25348397 27898060 N/A in vitro ComPPI,OmniPath
KIFAP3 GAP43 25348397 N/A physical interaction ComPPI
PRKCB GAP43 14525934 2140056 25348397 8694767 N/A experimental interaction detection,in vitro ComPPI,HPRD
CSNK2A1 GAP43 14525934 1828073 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SPTAN1 GAP43 10521589 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
RABEP1 GAP43 14525934 25348397 27898060 9742146 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CCR1 GAP43 25348397 N/A physical interaction ComPPI
PLCD1 GAP43 12805215 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
BIRC2 GAP43 25348397 N/A physical interaction ComPPI
CCNL2 GAP43 25348397 N/A physical interaction ComPPI
GDE1 GAP43 25348397 N/A physical interaction ComPPI
S1PR2 GAP43 25348397 N/A physical interaction ComPPI
GAP43 SLC25A41 25348397 N/A physical interaction ComPPI
GAP43 TMEM185A 25348397 N/A physical interaction ComPPI
GAP43 PCDHGC3 25348397 N/A physical interaction ComPPI
GAP43 GJB7 25348397 N/A physical interaction ComPPI
GAP43 TIGD5 25348397 N/A physical interaction ComPPI
GAP43 MARVELD2 25348397 N/A physical interaction ComPPI
GAP43 CYP2S1 25348397 N/A physical interaction ComPPI
GAP43 PCK2 25348397 N/A physical interaction ComPPI
GAP43 CALM2 12805215 14525934 8900147 N/A experimental interaction detection HPRD
PRKCA GAP43 2562806 27898060 7891109 stimulant N/A OmniPath

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