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GENE：GPX3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPX3
FullNmae glutathione peroxidase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4555
EnsembleID ENSG00000211445
Uniprot P22352

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPX3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPX3 GO:0004602,GO:0004602,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0006982,GO:0008430,GO:0008430,GO:0042744,GO:0042744,GO:0042802,GO:0070062,GO:0098869

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GPX3 hsa:2878 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
GPX3 hsa:2878 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GPX3 hsa:2878 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)
GPX3 hsa:2878 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
GPX3 hsa:2878 path:hsa05016 Huntington disease - Homo sapiens (human)
GPX3 hsa:2878 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR2 GPX3 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 GPX3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GPX3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GPX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GPX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GPX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GPX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GPX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GPX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GPX3 N/A trascriptional regulation,stimulation inferred by curator TFlink
HIF1A GPX3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
UBQLN1 GPX3 25348397 N/A physical interaction ComPPI
TP53I3 GPX3 25348397 N/A physical interaction ComPPI

Visualization










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