Gene Information gene info

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GENE：HOOK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HOOK1
FullNmae hook microtubule tethering protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19884
EnsembleID ENSG00000134709
Uniprot Q9UJC3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HOOK1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HOOK1 lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HOOK1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HOOK1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HOOK1 GO:0003779,GO:0005515,GO:0005737,GO:0005737,GO:0005813,GO:0005829,GO:0005874,GO:0007030,GO:0007032,GO:0007040,GO:0008017,GO:0008333,GO:0015031,GO:0030705,GO:0031122,GO:0042802,GO:0042803,GO:0045022,GO:0051959,GO:0070695,GO:1905198,GO:1905719

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 HOOK1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF HOOK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HOOK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 HOOK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A HOOK1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 HOOK1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 HOOK1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00004719AB HOOK1 21572407 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D HOOK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 HOOK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 HOOK1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001F9A0F HOOK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 HOOK1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 HOOK1 21572407 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A HOOK1 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS00000AD02D HOOK1 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase

Source Target Pmid Interactiontype Methods Database
PIAS2 HOOK1 25348397 N/A two hybrid ComPPI
CDC5L HOOK1 17043677 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D7 HOOK1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RABGGTB HOOK1 25348397 N/A physical interaction ComPPI
VCP HOOK1 25348397 N/A physical interaction ComPPI
CDC16 HOOK1 25348397 N/A physical interaction ComPPI
TRIP11 HOOK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TNFSF13B HOOK1 25348397 N/A physical interaction ComPPI
LMO2 HOOK1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TFIP11 HOOK1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ANK3 HOOK1 14525934 15823567 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
CDK4 HOOK1 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
AKTIP HOOK1 14525934 17353931 18799622 24234451 25348397 25416956 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
HOOK1 HOOK3 14525934 18799622 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
HOOK1 USP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HOOK1 SYCE1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HOOK1 CWF19L2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOOK1 ZNF80 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
H3-4 HOOK1 24234451 30021884 physical association cross-linking study IntAct

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